Search Results - "Ross, D M"

Spatial patterns of climate change across the Paleocene-Eocene Thermal Maximum by Tierney, Jessica E, Zhu, Jiang, Li, Mingsong, Ridgwell, Andy, Hakim, Gregory J, Poulsen, Christopher J, Whiteford, Ross D M, Rae, James W B, Kump, Lee R

“…The Paleocene-Eocene Thermal Maximum (PETM; 56 Ma) is one of our best geological analogs for understanding climate dynamics in a "greenhouse" world. However,…”
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Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR by Ross, D M, Branford, S, Seymour, J F, Schwarer, A P, Arthur, C, Bartley, P A, Slader, C, Field, C, Dang, P, Filshie, R J, Mills, A K, Grigg, A P, Melo, J V, Hughes, T P

“…Around 40–50% of patients with chronic myeloid leukemia (CML) who achieve a stable complete molecular response (CMR; undetectable breakpoint cluster…”
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The APOL1 Genotype of African American Kidney Transplant Recipients Does Not Impact 5‐Year Allograft Survival by Lee, B. T, Kumar, V, Williams, T. A, Abdi, R, Bernhardy, A, Dyer, C, Conte, S, Genovese, G, Ross, M. D., Friedman, D.J., Gaston, R., Milford, E., Pollak, M. R., Chandraker, A.

“…Apolipoprotein L‐1 (APOL1) gene variants are associated with end‐stage renal disease in African Americans (AAs). Here we investigate the impact of recipient…”
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A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone by Hahn, C N, Ross, D M, Feng, J, Beligaswatte, A, Hiwase, D K, Parker, W T, Ho, M, Zawitkowski, M, Ambler, K L, Cheetham, G D, Lee, Y K, Babic, M, Butcher, C M, Engler, G A, Brown, A L, D'Andrea, R J, Lewis, I D, Schreiber, A W, To, L B, Scott, H S

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A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm by Casolari, D. A., Nguyen, T., Butcher, C. M., Iarossi, D. G., Hahn, C. N., Bray, S. C., Neufing, P., Parker, W. T., Feng, J., Maung, K. Z. Y., Wee, A., Vidovic, L., Kok, C. H., Bardy, P. G., Branford, S., Lewis, I. D., Lane, S. W., Scott, H. S., Ross, D. M., D’Andrea, R. J.

“…We describe a novel ERBB1/EGFR somatic mutation (p. C329R; c.985 T > C) identified in a patient with JAK2 V617F Polycythaemia Vera (PV). This substitution…”
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Limited clinical value of regular bone marrow cytogenetic analysis in imatinib-treated chronic phase CML patients monitored by RQ-PCR for BCR-ABL by ROSS, D. M, BRANFORD, S, MOORE, S, HUGHES, T. P

“…Real-time quantitative polymerase chain reaction (PCR) for BCR-ABL mRNA in the peripheral blood (RQ-PCR) provides an accurate and reliable measure of response…”
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Responses to pomalidomide and placebo in myelofibrosis-related anaemia by Ross, D M

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Treatment-free remission following frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the ENESTfreedom study by Hochhaus, A, Masszi, T, Giles, F J, Radich, J P, Ross, D M, Gómez Casares, M T, Hellmann, A, Stentoft, J, Conneally, E, García-Gutiérrez, V, Gattermann, N, Wiktor-Jedrzejczak, W, le Coutre, P D, Martino, B, Saussele, S, Menssen, H D, Deng, W, Krunic, N, Bedoucha, V, Saglio, G

“…The single-arm, phase 2 ENESTfreedom trial assessed the potential for treatment-free remission (TFR; i.e., the ability to maintain a molecular response after…”
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A novel SNP in COMT is associated with alcohol dependence but not opiate or nicotine dependence: a case control study by Voisey, Joanne, Swagell, Christopher D, Hughes, Ian P, Lawford, Bruce R, Young, Ross M D, Morris, C Phillip

“…It is well established that COMT is a strong candidate gene for substance use disorder and schizophrenia. Recently we identified two SNPs in COMT (rs4680 and…”
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Cancer treatment with kinase inhibitors: what have we learnt from imatinib? by ROSS, D. M, HUGHES, T. P

“…Over the past few years, a number of anticancer drugs have been developed that specifically target kinases known to be oncogenic. The leading drug in this area…”
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Atmospheric CO2 over the Past 66 Million Years from Marine Archives by Rae, James W.B, Zhang, Yi Ge, Liu, Xiaoqing, Foster, Gavin L, Stoll, Heather M, Whiteford, Ross D.M

“…Throughout Earth's history, CO 2 is thought to have exerted a fundamental control on environmental change. Here we review and revise CO 2 reconstructions from…”
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Changes in Ribbon Synapses and Rough Endoplasmic Reticulum of Rat Utricular Macular Hair Cells in Weightlessness by Ross, Muriel D.

“…This study combined ultrastructural and statistical methods to learn the effects of weightlessness on rat utricular maculae. A principle aim was to determine…”
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Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury by Hartings, Jed A, Andaluz, Norberto, Bullock, M Ross, Hinzman, Jason M, Mathern, Bruce, Pahl, Clemens, Puccio, Ava, Shutter, Lori A, Strong, Anthony J, Vagal, Achala, Wilson, J Adam, Dreier, Jens P, Ngwenya, Laura B, Foreman, Brandon, Pahren, Laura, Lingsma, Hester, Okonkwo, David O

“…Advances in treatment of traumatic brain injury are hindered by the inability to monitor pathological mechanisms in individual patients for targeted…”
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Do we have to kill the last CML cell? by Ross, D M, Hughes, T P, Melo, J V

“…Previous experience in the treatment of chronic myeloid leukaemia (CML) has shown that the achievement of clinical, morphological and cytogenetic remission…”
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Detection and localization of HIV-1 DNA in renal tissues by in situ polymerase chain reaction by Tanji, N, Ross, M D, Tanji, K, Bruggeman, L A, Markowitz, G S, Klotman, P E, D'Agati, V D

“…The localization of HIV-1 DNA in renal tissues is critically important for understanding pathogenesis of HIV-associated nephropathy (HIVAN), but the…”
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Assessment of early paraprotein response to vincristine-doxorubicin-dexamethasone chemotherapy may help guide therapy in multiple myeloma by Ross, D. M., To, L. B., Horvath, N.

“…Vincristine, doxorubicin and dexamethasone (VAD) are commonly used as the initial chemotherapy in myeloma patients prior to high‐dose therapy and autologous…”
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Predicting Carotid Artery Disease and Plaque Instability from Cell-derived Microparticles by Wekesa, A.L, Cross, K.S, O'Donovan, O, Dowdall, J.F, O'Brien, O, Doyle, M, Byrne, L, Phelan, J.P, Ross, M.D, Landers, R, Harrison, M

“…Objectives Cell-derived microparticles (MPs) are small plasma membrane-derived vesicles shed from circulating blood cells and may act as novel biomarkers of…”
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Development of Squamous Cell Carcinoma After Pulmonary Aspergillosis in the Native Lung of a Lung Transplant Recipient: A Case Report by Madan, N., Abdelrazek, H., Patil, P.D., Ross, M.D., Roy, S.B., Thawani, N., Hahn, M.F., Bremner, R.M., Panchabhai, T.S.

“…Lung transplant recipients have a significant incidence of posttransplant lung nodules. Such nodules can occur from various etiologies, both in the lung…”
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Delayed diagnosis leading to accelerated-phase chronic eosinophilic leukemia due to a cytogenetically cryptic, imatinib-responsive TNIP1–PDFGRB fusion gene by Ross, D M, Altamura, H K, Hahn, C N, Nicola, M, Yeoman, A L, Holloway, M R, Geoghegan, J, Feng, J, Schreiber, A W, Branford, S, Moore, S, Scott, H S

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Alectinib in ALK -positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial by Shaw, Alice T, Dr, Gandhi, Leena, MD, Gadgeel, Shirish, Prof, Riely, Gregory J, MD, Cetnar, Jeremy, MD, West, Howard, MD, Camidge, D Ross, MD, Socinski, Mark A, Prof, Chiappori, Alberto, MD, Mekhail, Tarek, MD, Chao, Bo H, MD, Borghaei, Hossein, DO, Gold, Kathryn A, MD, Zeaiter, Ali, MD, Bordogna, Walter, PhD, Balas, Bogdana, MD, Puig, Oscar, PhD, Henschel, Volkmar, PhD, Ou, Sai-Hong Ignatius, Prof

“…Summary Background Alectinib—a highly selective, CNS-active, ALK inhibitor—showed promising clinical activity in crizotinib-naive and crizotinib-resistant…”
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