Search Results - "Ross, C J"

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging by Silva-Cayetano, Alyssa, Fra-Bido, Sigrid, Robert, Philippe A., Innocentin, Silvia, Burton, Alice R., Watson, Emily M., Lee, Jia Le, Webb, Louise M. C., Foster, William S., McKenzie, Ross C. J., Bignon, Alexandre, Vanderleyden, Ine, Alterauge, Dominik, Lemos, Julia P., Carr, Edward J., Hill, Danika L., Cinti, Isabella, Balabanian, Karl, Baumjohann, Dirk, Espeli, Marion, Meyer-Hermann, Michael, Denton, Alice E., Linterman, Michelle A.

“…The magnitude and quality of the germinal center (GC) response decline with age, resulting in poor vaccine-induced immunity in older individuals. A functional…”
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Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children by Pussegoda, K, Ross, C J, Visscher, H, Yazdanpanah, M, Brooks, B, Rassekh, S R, Zada, Y F, Dubé, M-P, Carleton, B C, Hayden, M R

“…Cisplatin is a widely used chemotherapeutic agent for the treatment of solid tumors. A serious complication of cisplatin treatment is permanent hearing loss…”
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HLA-A31:01 and HLA-B15:02 as Genetic Markers for Carbamazepine Hypersensitivity in Children by Amstutz, U, Ross, C J D, Castro-Pastrana, L I, Rieder, M J, Shear, N H, Hayden, M R, Carleton, B C

“…The occurrence of hypersensitivity reactions including rare but life‐threatening Stevens–Johnson syndrome (SJS) and drug‐induced hypersensitivity syndrome…”
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Viraemia and Ebola virus secretion in survivors of Ebola virus disease in Sierra Leone: a cross-sectional cohort study by Green, Edward, Dr, Hunt, Luke, MBChB, Ross, J C Gareth, BSc, Nissen, Nina Marie, BSc, Curran, Tanya, PhD, Badhan, Anjna, PhD, Sutherland, Katherine A, PhD, Richards, Jade, Lee, James S, MD, Allen, Samuel H, FRCP, Laird, Steven, MRCP, Blackman, Mandy, Collacott, Ian, BSc, Parker, Paul A, BSc, Walbridge, Andrew, MSc, Phillips, Rebecca, BSc, Sellu, Sia Jammie, Dama, Agnes, Sheriff, Alpha Karim, MBChB, Zombo, Joseph, Ngegba, Doris, Wurie, Alieh H, MD, Checchi, Francesco, PhD, Brooks, Timothy J, FRCPath

“…Summary Background In survivors of Ebola virus disease, clinical sequelae including uveitis, arthralgia, and fatigue are common and necessitate systematic…”
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Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications by Oberlander, T F, Bonaguro, R J, Misri, S, Papsdorf, M, Ross, C J D, Simpson, E M

“…Reduced Apgar scores and birth weight, increased risk of respiratory distress, jitteriness and increased tone have been reported in up to 30% of neonates with…”
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Trends in sexually transmitted infections (other than HIV) in older people: analysis of data from an enhanced surveillance system by Bodley-Tickell, A T, Olowokure, B, Bhaduri, S, White, D J, Ward, D, Ross, J D C, Smith, G, Duggal, H V, Goold, P

“…This study examines the distribution of selected sexually transmitted infections (STIs) in older people (aged >/=45 years) attending genitourinary medicine…”
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Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent by Aminkeng, F, Ross, C J D, Rassekh, S R, Brunham, L R, Sistonen, J, Dube, M-P, Ibrahim, M, Nyambo, T B, Omar, S A, Froment, A, Bodo, J-M, Tishkoff, S, Carleton, B C, Hayden, M R

“…There is established clinical evidence for differences in drug response, cure rates and survival outcomes between different ethnic populations, but the causes…”
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Pulmonary Vascular Morphology as an Imaging Biomarker in Chronic Thromboembolic Pulmonary Hypertension by Rahaghi, F. N., Ross, J. C., Agarwal, M., González, G., Come, C. E., Diaz, A. A., Vegas-Sánchez-Ferrero, G., Hunsaker, A., Estépar, R. San José, Waxman, A. B., Washko, G. R.

“…Patients with chronic thromboembolic pulmonary hypertension (CTEPH) have morphologic changes to the pulmonary vasculature. These include pruning of the distal…”
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The global spectrum of protein-coding pharmacogenomic diversity by Wright, G E B, Carleton, B, Hayden, M R, Ross, C J D

“…Differences in response to medications have a strong genetic component. By leveraging publically available data, the spectrum of such genomic variation can be…”
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Application of principal component analysis to pharmacogenomic studies in Canada by Visscher, H, Ross, C J D, Dubé, M-P, Brown, A M K, Phillips, M S, Carleton, B C, Hayden, M R

“…Ethnicity can confound results in pharmacogenomic studies. Allele frequencies of loci that influence drug metabolism can vary substantially between different…”
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Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels by Vaessen, S.F.C., Dallinga-Thie, G.M., Ross, C.J.D., Splint, L.J., Castellani, L.W., Rensen, P.C.N., Hayden, M.R., Schaap, F.G., Kuivenhoven, J.A.

“…Apolipoprotein AV (apoAV) overexpression causes a decrease in plasma triglyceride (TG) levels, while deficiency of apoAV causes hypertriglyceridemia in both…”
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Pharmacogenetics of Neonatal Opioid Toxicity Following Maternal Use of Codeine During Breastfeeding: A Case-Control Study by Madadi, P, Ross, CJD, Hayden, MR, Carleton, BC, Gaedigk, A, Leeder, JS, Koren, G

“…A large number of women receive codeine for obstetric pain while breastfeeding. Following a case of fatal opioid poisoning in a breastfed neonate whose codeine…”
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The influence of the noradrenergic/stress system on perceptual biases for reward by Ehlers, M. R., Ross, C. J. D., Todd, R. M.

“…Previous research has established a role for the norepinephrine (NE)/stress system in individual differences in biases to attend to reward or punishment…”
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Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children by Visscher, H., Ross, C.J.D., Rassekh, S.R., Sandor, G.S.S., Caron, H.N., van Dalen, E.C., Kremer, L.C., van der Pal, H.J., Rogers, P.C., Rieder, M.J., Carleton, B.C., Hayden, M.R.

“…Background . The use of anthracyclines as effective antineoplastic drugs is limited by the occurrence of cardiotoxicity. Multiple genetic variants predictive…”
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Treatment of a lysosomal storage disease, mucopolysaccharidosis VII, with microencapsulated recombinant cells by Ross, C J, Bastedo, L, Maier, S A, Sands, M S, Chang, P L

“…Most lysosomal enzyme deficiencies are catastrophic illnesses with no generally available treatments. We have used the beta-glucuronidase-deficient mouse model…”
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Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin by Brunham, L R, Lansberg, P J, Zhang, L, Miao, F, Carter, C, Hovingh, G K, Visscher, H, Jukema, J W, Stalenhoef, A F, Ross, C J D, Carleton, B C, Kastelein, J J P, Hayden, M R

“…Statins reduce cardiovascular morbidity and mortality in appropriately selected patients. However, statin-associated myopathy is a significant risk associated…”
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Mycoplasma genitalium as a sexually transmitted infection: implications for screening, testing, and treatment by Ross, J D C, Jensen, J S

“…The evidence that Mycoplasma genitalium is a sexually transmitted pathogen is virtually incontrovertible based on both the concordance rates among partners and…”
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Placental transport and fetal utilization of leucine in a model of fetal growth retardation by Ross, J.C. (University of Colorado School of Medicine, Denver, CO.), Fennessey, P.V, Wilkening, R.B, Battaglia, F.C, Meschia, G

“…Placental transport and fetal utilization of leucine were studied at 130 days of gestation in six control ewes and in seven ewes in which intrauterine growth…”
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Prediction of Codeine Toxicity in Infants and Their Mothers Using a Novel Combination of Maternal Genetic Markers by Sistonen, J, Madadi, P, Ross, C J, Yazdanpanah, M, Lee, J W, Landsmeer, M L A, Nauta, M, Carleton, B C, Koren, G, Hayden, M R

“…Substantial variation exists in response to standard doses of codeine ranging from poor analgesia to life‐threatening central nervous system (CNS) depression…”
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The emerging era of pharmacogenomics: current successes, future potential, and challenges by Lee, J.W., Aminkeng, F., Bhavsar, A.P., Shaw, K., Carleton, B.C., Hayden, M.R., Ross, C.J.D.

“…The vast range of genetic diversity contributes to a wonderful array of human traits and characteristics. Unfortunately, a consequence of this genetic…”
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