Search Results - "Rosok, MJ"

A Combinatorial Library Strategy for the Rapid Humanization of Anticarcinoma BR96 Fab by Rosok, M J, Yelton, D E, Harris, L J, Bajorath, J, Hellström, K E, Hellström, I, Cruz, G A, Kristensson, K, Lin, H, Huse, W D, Glaser, S M

“…We have used a combinatorial mutagenesis strategy to humanize BR96, a monoclonal antibody that binds to the Lewis Y class of tumor antigens. This approach…”
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Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesis by Yelton, DE, Rosok, MJ, Cruz, G, Cosand, WL, Bajorath, J, Hellstrom, I, Hellstrom, KE, Huse, WD, Glaser, SM

“…We have increased up to 65-fold the avidity of BR96, a mAb recognizing Lewis Y (Le(y))-related Ags expressed on the surface of many human carcinomas. Libraries…”
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Analysis of BR96 Binding Sites for Antigen and Anti-Idiotype by Codon-Based Scanning Mutagenesis by Rosok, Mae Joanne, Eghtedarzadeh-Kondri, Mohammad, Young, Kelly, Bajorath, Jurgen, Glaser, Scott, Yelton, Dale

“…We performed a scanning mutagenesis study of heavy chain complementarity-determining region (CDR) residues to identify how mutations affected binding of the…”
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Generation and characterization of murine antiflagellum monoclonal antibodies that are protective against lethal challenge with Pseudomonas aeruginosa by ROSOK, M. J, STEBBINS, M. R, CONNELLY, K, LOSTROM, M. E, SIADAK, A. W

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Transformation parameters and pp60src localization in cells infected with partial transformation mutants of Rous sarcoma virus by Rohrschneider, L, Rosok, M J

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Transformation parameters and pp60 super(src) localization in cells infected with partial transformation mutants of Rous sarcoma virus by Rohrschneider, L, Rosok, MJ

“…Rous sarcoma virus (RSV)-induced transformation is mediated by the action of the viral src gene product pp60 super(src). This transforming protein is found at…”
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Increased phosphorylation of vinculin on tyrosine does not occur during the release of stress fibers before mitosis in normal cells by Rosok, M J, Rohrschneider, L R

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Evaluation of an immunofluorescent-antibody test for rapid identification of Pseudomonas aeruginosa in blood cultures by COUNTS, G. W, SCHWARTZ, R. W, ULNESS, B. K, HAMILTON, D. J, ROSOK, M. J, CUNNINGHAM, M. D, TAM, M. R, DARVEAU, R. P

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Molecular interaction of the src gene product with cellular adhesion plaques by Rohrschneider, L R, Rosok, M J, Gentry, L E

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Model RNA-directed DNA synthesis by avian myeloblastosis virus DNA polymerase and its associated RNase H by Watson, Kenneth F, Schendel, Peter L, Rosok, Mae J, Ramsey, Leonard R

“…A model RNA template-primer system is described for the study of RNA-directed double-stranded DNA synthesis by purified avian myeloblastosis virus DNA…”
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