Search Results - "Rosivall, László"
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Therapeutic Targeting of Fibrotic Epithelial-Mesenchymal Transition-An Outstanding Challenge
Published in Frontiers in pharmacology (18-04-2019)“…Back in 1995, a landmark paper was published, which shaped the fibrosis literature for many years to come. During the characterization of a fibroblast-specific…”
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Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome
Published in Nanomedicine (01-02-2012)“…Abstract Hypersensitivity reactions to liposomal drugs, often observed with Doxil and AmBisome, can arise from activation of the complement (C) system by…”
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Selective phosphodiesterase-5 (PDE-5) inhibitor vardenafil ameliorates renal damage in type 1 diabetic rats by restoring cyclic 3',5' guanosine monophosphate (cGMP) level in podocytes
Published in Nephrology, dialysis, transplantation (01-07-2013)“…Diabetic nephropathy (DN) is characterized by podocyte damage and increased phosphodiesterase-5 (PDE-5) activity-exacerbating nitric oxide (NO)-cyclic 3',5'…”
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Cinaciguat ameliorates glomerular damage by reducing ERK1/2 activity and TGF-ß expression in type-1 diabetic rats
Published in Scientific reports (11-09-2017)“…Decreased soluble guanylate cyclase activity and cGMP levels in diabetic kidneys were shown to influence the progression of nephropathy. The regulatory effects…”
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Impact of the first wave of COVID-19 pandemic on the Hungarian university students’ social and health behaviour
Published in Journal of public health (01-07-2023)“…Background The COVID-19 pandemic brought quick, severe and unexpected changes to our everyday life and also changed the traditional education pattern of…”
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Can chlorine dioxide prevent the spreading of coronavirus or other viral infections? Medical hypotheses
Published in Physiology international (01-03-2020)“…Viruses have caused many epidemics throughout human history. The novel coronavirus [10] is just the latest example. A new viral outbreak can be unpredictable,…”
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Integrity of cell-cell contacts is a critical regulator of TGF-β1-induced epithelial-to-myofibroblast transition role for β-catenin
Published in The American journal of pathology (01-12-2004)“…Injury of the tubular epithelium and TGF-β1-induced conversion of epithelial cells to α-smooth muscle actin (SMA)-expressing myofibroblasts are key features of…”
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Intrarenal renin–angiotensin system
Published in Molecular and cellular endocrinology (29-04-2009)“…Phylogenetically the renin–angiotensin system (RAS ) is an ancient regulatory system which has attracted the attention of researchers for about a century. As a…”
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Diagnosis and treatment of early renal disease in patients with type 2 diabetes mellitus: what are the clinical needs?
Published in Nephrology, dialysis, transplantation (01-08-2015)“…Renal disease is prevalent in patients with diabetes mellitus type 2. Aggressive metabolic control and lowering of systemic and/or intraglomerular blood…”
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The association of overhydration with chronic inflammation in chronic maintenance hemodiafiltration patients
Published in Hemodialysis international (01-07-2019)“…Introduction: Achieving euvolemia is one of the major challenges when treating end‐stage renal disease (ESRD) patients receiving maintenance renal replacement…”
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Expression of Vascular Endothelial Growth Factor Has a Regulatory Role in Gingival Venules in Experimental Diabetes
Published in Journal of periodontology (1970) (01-03-2016)“…Background: In the present study, the possible localization and role of vascular endothelial growth factor receptor type 2 (VEGFR2) in the regulation of…”
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Endothelial-mesenchymal transition of brain endothelial cells: possible role during metastatic extravasation
Published in PloS one (2015)“…Cancer progression towards metastasis follows a defined sequence of events described as the metastatic cascade. For extravasation and transendothelial…”
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Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
Published in ACS nano (27-08-2019)“…Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe hypersensitivity reactions (HSRs), which can occasionally be life threatening or…”
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Fluid flow in the juxtaglomerular interstitium visualized in vivo
Published in American journal of physiology. Renal physiology (01-12-2006)“…Earlier electron microscopy studies demonstrated morphological signs of fluid flow in the juxtaglomerular apparatus (JGA), including fenestrations of the…”
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Volume-related weight gain as an independent indication for renal replacement therapy in the intensive care units
Published in Journal of renal injury prevention (2017)“…Attempts to identify specific therapies to reverse acute kidney injury (AKI) have been unsuccessful in the past; only modifying risk profile or addressing the…”
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Heterogeneity of the afferent arteriole—correlations between morphology and function
Published in Nephrology, dialysis, transplantation (01-10-2006)Get full text
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Budapest nephrology school – 30 years of history – from modest start to an international success: systematic summary of the 27th BNS held between 28th August and 2nd of September 2023
Published in Renal failure (01-12-2024)“…Budapest Nephrology School (BNS) could have celebrated its 30th event if it had not been interrupted by COVID pandemic for a few years. Yet, the organization…”
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Complement activation by polyethoxylated pharmaceutical surfactants: Cremophor-EL, Tween-80 and Tween-20
Published in European journal of pharmaceutical sciences (12-03-2012)“…Immunosafety analysis of pharmaceutical surfactants is an important step in understanding the complex mechanisms by which they induce side effects in…”
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A porcine model of complement-mediated infusion reactions to drug carrier nanosystems and other medicines
Published in Advanced drug delivery reviews (01-12-2012)“…Intravenous administration of low (milligram) doses of nanoparticulate materials in pigs can lead to acute cardiopulmonary, hemodynamic, hematological,…”
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