Search Results - "Rosinger, S."
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Low content of the natural ocular anti-angiogenic agent pigment epithelium-derived factor (PEDF) in aqueous humor predicts progression of diabetic retinopathy
Published in Diabetologia (01-03-2003)“…Retinopathy is the most common microvascular complication of diabetes. Our aim was to address the predictive value of pro-angiogenic and anti-angiogenic…”
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Elevated serum levels of N(epsilon)-carboxymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema
Published in Diabetologia (01-08-2004)“…Diabetic retinopathy is a frequent microvascular complication. In search of novel risk markers, we analysed the association between serum levels of the major…”
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Pollen competition in hybridizing Cakile species: How does a latecomer win the race?
Published in American journal of botany (01-08-2022)“…Premise Hybridization between cross‐compatible species depends on the extent of competition between alternative mates. Even if stigmatic compatibility allows…”
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The radiation of Austral teals (Aves: Anseriformes) and the evolution of flightlessness
Published in Zoological journal of the Linnean Society (01-08-2024)“…Abstract The origin and evolution in the Southern Hemisphere of the Austral teals, consisting of the grey-teal and brown-teal species complexes, remains poorly…”
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Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB104, DQ8 Type 1 diabetes
Published in Diabetologia (01-03-2004)“…Preproinsulin is a target T cell autoantigen in human Type 1 diabetes. This study analyses the phenotype and epitope recognition of preproinsulin reactive T…”
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The tip of the iceberg: Genome wide marker analysis reveals hidden hybridization during invasion
Published in Molecular ecology (01-02-2021)“…Biological invasions are accelerating, and invasive species can have large economic impacts as well as severe consequences for biodiversity. During invasions,…”
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MHC-environment interactions leading to type 1 diabetes: feasibility of an analysis of HLA DR-DQ alleles in relation to manifestation periods and dates of birth
Published in Diabetes, obesity & metabolism (01-02-2009)“…The region on chromosome 6p21 (IDDM1) confers the largest part of genetic susceptibility to type 1 diabetes (T1D) with particular human leucocyte antigen (HLA)…”
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The HMG-CoA reductase inhibitor cerivastatin lowers advanced glycation end products in patients with type 2 diabetes
Published in Experimental and clinical endocrinology & diabetes (01-06-2007)“…Although the association between type 2 diabetes mellitus (DM) and cardiovascular diseases is well-documented, current knowledge regarding reasons for the…”
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Mating in parents of type 1 diabetes families as a function of the HLA DR-DQ haplotype
Published in Diabetes, obesity & metabolism (01-02-2009)“…The Major Histocompatibility Complex (MHC) region on chromosome 6p21 (IDDM1) contributes about half of the familial clustering of type 1 diabetes (T1D)…”
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Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements
Published in Archives of toxicology (01-01-2018)“…Arsenic is one of the most important human carcinogens and environmental pollutants. However, the evaluation of the underlying carcinogenic mechanisms is…”
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Proliferative diabetic retinopathy is associated with a low level of the natural ocular anti-angiogenic agent pigment epithelium-derived factor (PEDF) in aqueous humor. a pilot study
Published in Hormone and metabolic research (01-06-2003)“…Retinopathy is the most common microvascular diabetes complication and represents a major threat to the eyesight. The aim of this study was to address the role…”
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Glutamic acid decarboxylase and islet antigen 2 antibody profiles in people with adult‐onset diabetes mellitus: a comparison between mixed ethnic populations in Singapore and Germany
Published in Diabetic medicine (01-08-2017)“…Aim To gain insight into the presence of islet cell autoimmunity in an ethnic Asian compared with a white European population. Methods For this cross‐sectional…”
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Coexpression of CD25 and OX40 (CD134) Receptors Delineates Autoreactive T-cells in Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-01-2006)“…Coexpression of CD25 and OX40 (CD134) Receptors Delineates Autoreactive T-cells in Type 1 Diabetes Josef Endl 1 , Silke Rosinger 2 , Barbara Schwarz 1 ,…”
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Mating in parents of type 1 diabetes families as a function of the HLA DR-DQ haplotype
Published in Diabetes, obesity & metabolism (01-02-2009)Get full text
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DRB10401-Restricted Human T Cell Clone Specific for the Major Proinsulin73-90 Epitope Expresses a Down-Regulatory T Helper 2 Phenotype
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-2006)“…Recently, we have identified proinsulin $(P-Ins)_{73-90}$ as an immunodominant T cell epitope of HLA-DRB1*0401 (DR4) subjects with β-islet cell autoimmunity…”
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Preproinsulin-Specific CD8+ T Cells Secrete IFNγ in Human Type 1 Diabetes
Published in Annals of the New York Academy of Sciences (01-12-2004)“…: In animal models autoreactive CD8+ T cells are crucial in the development of type 1 diabetes (T1D); however, their role in human T1D is still not known. To…”
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Th2 Dominance of T Helper Cell Response to Preproinsulin in Individuals with Preclinical Type 1 Diabetes
Published in Annals of the New York Academy of Sciences (01-04-2002)“…: In human type 1 diabetes (T1D) autoantibodies to insulin precede clinical disease, while little is known about the contribution of insulin‐specific T…”
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Data centres for IoT applications: The M2DC approach (Invited paper)
Published in 2016 International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation (SAMOS) (01-07-2016)“…The Modular Microserver DataCentre (M2DC) project investigates, develops and demonstrates a modular, highly-efficient, cost-optimized server architecture…”
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