Search Results - "Roshaiah, M."

Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists by Sasmal, Pradip K., Krishna, C. Vamsee, Adabala, S. Sudheerkumar, Roshaiah, M., Rawoof, Khaji Abdul, Thadi, Emima, Sukumar, K. Pavan, Cheera, Srisailam, Abbineni, Chandrasekhar, Rao, K.V.L. Narasimha, Prasanthi, A., Nijhawan, Kamal, Jaleel, Mahaboobi, Iyer, Lakshmi Ramachandran, Chaitanya, T. Krishna, Tiwari, Nirbhay Kumar, Krishna, N. Lavanya, Potluri, Vijay, Khanna, Ish, Frimurer, Thomas M., Lückmann, Michael, Rist, Øystein, Elster, Lisbeth, Högberg, Thomas

“…[Display omitted] Kappa opioid receptor (KOR) is an important mediator of pain signaling and it is targeted for the treatment of various pains. Pharmacophore…”
Get full text

Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists by Sasmal, Pradip K., Sasmal, Sanjita, Rao, P. Tirumala, Venkatesham, B., Roshaiah, M., Abbineni, Chandrasekhar, Khanna, Ish, Jadhav, Vikram P., Suresh, J., Talwar, Rashmi, Muzeeb, Syed, Receveur, Jean-Marie, Frimurer, Thomas M., Rist, Øystein, Elster, Lisbeth, Högberg, Thomas

“…The synthesis and biological evaluation of novel benzimidazole derivatives as MCHR1 antagonists are described. The in vivo proof of principle for weight loss…”
Get full text

Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones by Das, Jagattaran, Rao, C.V. Laxman, Sastry, T.V.R.S., Roshaiah, M., Sankar, P. Gowri, Khadeer, Abdul, Kumar, M. Sitaram, Mallik, Arundhuti, Selvakumar, N., Iqbal, Javed, Trehan, Sanjay

“…Some novel oxazolidinone derivatives have been synthesized and tested for antibacterial activity. Compound 13 was found to be active against Gram-positive…”
Get full text

Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones by Das, Jagattaran, Sitaram Kumar, M., Subrahmanyam, D., Sastry, T.V.R.S., Prasad Narasimhulu, C., Laxman Rao, C.V., Kannan, M., Roshaiah, M., Awasthi, Riti, Patil, Santosh N., Sarnaik, H.M., Rao Mamidi, N.V.S., Selvakumar, N., Iqbal, Javed

“…The synthesis of a series of tricyclic oxazolidinones is disclosed. SAR studies on these novel compounds and evaluation of a lead compound are reported. In an…”
Get full text