Search Results - "Rosenthal, K"
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Calcium Pyrophosphate Deposition Disease
Published in The New England journal of medicine (30-06-2016)“…CPPD disease (also called pseudogout) is common, especially among persons older than 60 years of age, but it is underrecognized and undertreated. This review…”
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Pathogenesis of calcium pyrophosphate deposition disease
Published in Best practice & research. Clinical rheumatology (01-12-2021)“…Calcium pyrophosphate deposition disease is defined by the presence of calcium pyrophosphate (CPP) crystals in articular cartilage and is the fourth most…”
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Hypermethylation of the miR-155 gene in the whole blood and decreased plasma level of miR-155 in rheumatoid arthritis
Published in PloS one (02-06-2020)“…Objectives miR-155 plays a critical role in the inflammatory process and in diseases such as rheumatoid arthritis (RA). miR155 gene expression is regulated by…”
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Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates
Published in The Journal of infectious diseases (05-11-2018)“…Bispecific antibody MEDI3902, targeting the Pseudomonas aeruginosa type 3 secretion system (PcrV) and Psl exopolysaccharide, is currently in phase 2b…”
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Evaluation of SNAP cPL, Spec cPL, VetScan cPL Rapid Test, and Precision PSL Assays for the Diagnosis of Clinical Pancreatitis in Dogs
Published in Journal of veterinary internal medicine (01-03-2018)“…Background The sensitivity, specificity, and agreement of 4 diagnostic assays (SNAP canine pancreatic lipase (cPL), specific cPL (Spec cPL), VetScan cPL Rapid…”
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Long-term follow-up after rituximab for steroid-dependent idiopathic nephrotic syndrome
Published in Nephrology, dialysis, transplantation (01-05-2012)“…In patients with refractory steroid-sensitive nephrotic syndrome (SSNS), treatment with rituximab has shown encouraging results; however, long-term follow-up…”
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Current data processing methods and reporting standards for untargeted analysis of volatile organic compounds using direct mass spectrometry: a systematic review
Published in Metabolomics (16-03-2024)“…Introduction Untargeted direct mass spectrometric analysis of volatile organic compounds has many potential applications across fields such as healthcare and…”
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The value of anti-CarP and anti-PAD4 as markers of rheumatoid arthritis in ACPA/RF negative rheumatoid arthritis patients
Published in Therapeutic advances in musculoskeletal disease (2021)“…Background: Anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are key factors in the American College of Rheumatology/European League…”
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Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models
Published in Antimicrobial agents and chemotherapy (01-11-2018)“…Alpha toxin (AT) is a cytolytic pore-forming toxin that plays a key role in pathogenesis; consequently, extensive research was undertaken to understand the AT…”
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Proteomic analysis of articular cartilage vesicles from normal and osteoarthritic cartilage
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2011)“…Objective Articular cartilage vesicles (ACVs) are extracellular organelles found in normal articular cartilage. While they were initially defined by their…”
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The Role of ANK in Calcium Pyrophosphate Deposition Disease
Published in Current rheumatology reports (01-05-2016)“…The protein product of the progressive ankylosis gene, known as ANK, is a 492-amino acid multi-pass transmembrane protein. This protein is critical for the…”
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Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach
Published in Antimicrobial agents and chemotherapy (01-08-2017)“…Secreted alpha-toxin and surface-localized clumping factor A (ClfA) are key virulence determinants in bloodstream infections. We previously demonstrated that…”
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Cell‐free synthesis of enzymes for the production of pharmaceutically relevant molecules
Published in Chemie ingenieur technik (01-09-2020)Get full text
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The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes
Published in Arthritis research & therapy (17-10-2013)“…Extracellular ATP (eATP) is released by articular chondrocytes under physiological and pathological conditions. High eATP levels cause pathologic…”
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The gp41 epitope, QARVLAVERY, is highly conserved and a potent inducer of IgA that neutralizes HIV-1 and inhibits viral transcytosis
Published in Mucosal immunology (01-09-2011)“…Mucosal surfaces are the predominant site of human immunodeficiency virus (HIV)-1 transmission. For prophylactic approaches to effectively prevent HIV…”
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Calcium pyrophosphate crystal size and characteristics
Published in Osteoarthritis and cartilage open (01-03-2021)“…To describe the characteristics of calcium pyrophosphate (CPP) crystal size and morphology under compensated polarized light microscopy (CPLM). Secondarily, to…”
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Update in calcium deposition diseases
Published in Current opinion in rheumatology (01-03-2007)“…PURPOSE OF REVIEWCalcium pyrophosphate dihydrate and basic calcium phosphate crystals are common components of osteoarthritic synovial fluids and define…”
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Erosive osteoarthritis: a systematic analysis of definitions used in the literature
Published in Seminars in arthritis and rheumatism (01-02-2017)“…Abstract Background Erosive osteoarthritis (EOA) is a commonly invoked diagnosis representing an important variant of hand osteoarthritis (OA). There is…”
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Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection
Published in Mucosal immunology (01-11-2015)“…Pulmonary tuberculosis (TB) remains to be a major global health problem despite many decades of parenteral use of Bacillus Calmette–Guérin (BCG) vaccine…”
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Upregulation of ANK Protein Expression in Joint Tissue in Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
Published in Journal of rheumatology (01-01-2014)“…Accumulation of excess extracellular inorganic pyrophosphate leads to calcium pyrophosphate dihydrate (CPPD) crystal formation in articular cartilage. CPPD…”
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