Search Results - "Rosenkranz, Anke C"

Regulation of Functionally Active P2Y12 ADP Receptors by Thrombin in Human Smooth Muscle Cells and the Presence of P2Y12 in Carotid Artery Lesions by Rauch, Bernhard H, Rosenkranz, Anke C, Ermler, Swen, Böhm, Andreas, Driessen, Julia, Fischer, Jens W, Sugidachi, Atsuhiro, Jakubowski, Joseph A, Schrör, Karsten

“…OBJECTIVE—The platelet P2Y12 ADP receptor is a well-known target of thienopyridine-type antiplatelet drugs. This study is the first to describe increased…”
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Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors by Kennedy, Jennifer A., Hua, Xiang, Mishra, Kumaril, Murphy, Geraldine A., Rosenkranz, Anke C., Horowitz, John D.

“…Calcific aortic stenosis displays some similarities to atherosclerosis including evidence of endothelial dysfunction. Whether nitric oxide (NO), which is…”
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Redox regulation of human protease-activated receptor-2 by activated factor X by Jobi, Klaus, Rauch, Bernhard H., Dangwal, Seema, Freidel, Kerstin, Doller, Anke, Eberhardt, Wolfgang, Fischer, Jens W., Schrör, Karsten, Rosenkranz, Anke C.

“…Activated factor X (FXa) exerts coagulation-independent actions such as proliferation of vascular smooth muscle cells (SMCs) through the protease-activated…”
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Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO and beyond by Ritchie, Rebecca H, Irvine, Jennifer C, Rosenkranz, Anke C, Patel, Ruchi, Wendt, Igor R, Horowitz, John D, Kemp-Harper, Barbara K

“…Left ventricular hypertrophy (LVH), an increased left ventricular (LV) mass, is common to many cardiovascular disorders, initially developing as an adaptive…”
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High Glucose Enhances Thrombin Responses via Protease-Activated Receptor-4 in Human Vascular Smooth Muscle Cells by Dangwal, Seema, Rauch, Bernhard H, Gensch, Thomas, Dai, Luru, Bretschneider, Ellen, Vogelaar, Christina Francisca, Schrör, Karsten, Rosenkranz, Anke C

“…OBJECTIVE—Diabetes is associated with vascular remodeling and increased thrombin generation. Thrombin promotes vascular smooth muscle cell (SMC) mitogenesis…”
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TGF-beta1-Induced MAPK activation promotes collagen synthesis, nodule formation, redox stress and cellular senescence in porcine aortic valve interstitial cells by Das, Dividutta, Holmes, Andrew, Murphy, Geraldine A, Mishra, Kumaril, Rosenkranz, Anke C, Horowitz, John D, Kennedy, Jennifer A

“…Aortic valve stenosis is a major cause of valve replacement, particularly in the elderly. TGF-beta1 is upregulated in stenotic valves and induces calcification…”
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Direct inhibitors of thrombin and factor Xa attenuate clot-induced mitogenesis and inflammatory gene expression in human vascular smooth muscle cells by Rosenkranz, Anke C, Schrör, Karsten, Rauch, Bernhard H

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B-type natriuretic peptide: endogenous regulator of myocardial structure, biomarker and therapeutic target by Ritchie, Rebecca H, Rosenkranz, Anke C, Kaye, David M

“…B-type natriuretic peptide (BNP), initially identified in brain tissues, is now recognized as a key cardiac hormone. Numerous studies over the last decade have…”
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Thrombin receptors in vascular smooth muscle cells - function and regulation by vasodilatory prostaglandins by Schrör, Karsten, Bretschneider, Ellen, Fischer, Kerstin, Fischer, Jens W, Pape, Robert, Rauch, Bernhard H, Rosenkranz, Anke C, Weber, Artur-Aron

“…The vast majority of thrombin (>95%) is generated after clotting is completed, suggesting that thrombin formation serves purposes beyond coagulation, such as…”
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Regulation of human vascular protease-activated receptor-3 through mRNA stabilization and the transcription factor nuclear factor of activated T cells (NFAT) by Rosenkranz, Anke C, Rauch, Bernhard H, Doller, Anke, Eberhardt, Wolfgang, Böhm, Andreas, Bretschneider, Ellen, Schrör, Karsten

“…Thrombin promotes vascular smooth muscle cell (SMC) proliferation and inflammation via protease-activated receptor (PAR)-1. A further thrombin receptor, PAR-3,…”
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Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT by Rosenkranz, Anke C., Rauch, Bernhard H., Freidel, Kerstin, Schrör, Karsten

“…Aims We recently reported that prostacyclin suppresses protease-activated receptor-1 (PAR-1) in human vascular smooth muscle cells (VSMC) via cyclic AMP and…”
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Transcriptional Inhibition of Protease-Activated Receptor-1 Expression by Prostacyclin in Human Vascular Smooth Muscle Cells by Pape, Robert, Rauch, Bernhard H, Rosenkranz, Anke C, Kaber, Gernot, Schrör, Karsten

“…OBJECTIVE—Stimulation of protease-activated receptor-1 (PAR-1) by thrombin causes vascular smooth muscle cell (SMC) mitogenesis and has been implicated in the…”
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Antihypertrophic actions of the natriuretic peptides in adult rat cardiomyocytes: importance of cyclic GMP by ROSENKRANZ, Anke C, WOODS, Robyn L, DUSTING, Gregory J, RITCHIE, Rebecca H

“…Atrial natriuretic peptide (ANP) prevents hypertrophy of neonatal cardiomyocytes. However, whether this effect is retained in the adult phenotype or if other…”
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Vitamin D2 supplementation induces the development of aortic stenosis in rabbits : Interactions with endothelial function and thioredoxin-interacting protein by NGO, Doan T. M, STAFFORD, Irene, KENNEDY, Jennifer A, HOROWITZ, John D, KELLY, Darren J, SVERDLOV, Aaron L, WUTTKE, Ronald D, WEEDON, Helen, NIGHTINGALE, Angus K, ROSENKRANZ, Anke C, SMITH, Malcolm D, CHIRKOV, Yuliy Y

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Endothelial antioxidant actions of dihydropyridines and angiotensin converting enzyme inhibitors by Rosenkranz, Anke C., Lob, Heinrich, Breitenbach, Thomas, Berkels, Reinhard, Roesen, Renate

“…Dihydropyridines and angiotensin converting enzyme inhibitor effects on superoxide and nitric oxide (NO) were compared in high glucose (20 mM, 24 h)-treated…”
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Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes by Rauch, Stefan J, Rosenkranz, Anke C, Böhm, Andreas, Meyer-Kirchrath, Jutta, Hohlfeld, Thomas, Schrör, Karsten, Rauch, Bernhard H

“…Abstract The activated leukocyte cell adhesion molecule (ALCAM/CD166) is associated with cell migration and leukocyte invasion into the vessel wall. This study…”
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B-Type natriuretic peptide prevents acute hypertrophic responses in the diabetic rat heart: Importance of cyclic GMP by ROSENKRANZ, Anke C, HOOD, Sally G, WOODS, Robyn L, DUSTING, Gregory J, RITCHIE, Rebecca H

“…Stimulation of cardiomyocyte guanosine 3',5'-cyclic monophosphate (cyclic GMP) via endothelial-derived nitric oxide (NO) is an important mechanism by which…”
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Acute Antihypertrophic Actions of Bradykinin in the Rat Heart: Importance of Cyclic GMP by Rosenkranz, Anke C, Hood, Sally G, Woods, Robyn L, Dusting, Gregory J, Ritchie, Rebecca H

“…ABSTRACT—The antihypertrophic action of angiotensin (Ang)-converting enzyme (ACE) inhibitors in the heart is attributed in part to potentiation of bradykinin…”
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Endothelial Dysfunction Limits the Antihypertrophic Action of Bradykinin in Rat Cardiomyocytes by Rosenkranz, Anke C, Dusting, Gregory J, Ritchie, Rebecca H

“…A. C. Rosenkranz, G. J. Dusting and R. H. Ritchie. Endothelial Dysfunction Limits the Antihypertrophic Action of Bradykinin in Rat Cardiomyocytes. Journal of…”
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B-Type Natriuretic Peptide Prevents Acute Hypertrophic Responses in the Diabetic Rat Heart by Rosenkranz, Anke C., Hood, Sally G., Woods, Robyn L., Dusting, Gregory J., Ritchie, Rebecca H.

“…B-Type Natriuretic Peptide Prevents Acute Hypertrophic Responses in the Diabetic Rat Heart Importance of Cyclic GMP Anke C. Rosenkranz 1 , Sally G. Hood 1 ,…”
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