Search Results - "Rosengren, R.J"

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    Sex- and strain-dependent effects of epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) in the mouse by Goodin, M.G., Bray, B.J., Rosengren, R.J.

    Published in Food and chemical toxicology (01-09-2006)
    “…We have previously demonstrated that 50 mg/kg of epigallocatechin gallate (EGCG) is hepatotoxic to female Swiss Webster mice, while lower doses of EGCG and…”
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    Journal Article
  3. 3

    Deer velvet supplementation decreases the grade and metastasis of azoxymethane-induced colon cancer in the male rat by Fraser, A., Haines, S.R., Stuart, E.C., Scandlyn, M.J., Alexander, A., Somers-Edgar, T.J., Rosengren, R.J.

    Published in Food and chemical toxicology (01-05-2010)
    “…Since deer velvet (DV) extract promotes angiogenesis, its ability to modulate the growth and invasiveness of colon tumours was investigated. Male Wistar rats…”
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    Journal Article
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    The effect of metformin in EML4-ALK+ lung cancer alone and in combination with crizotinib in cell and rodent models by Bland, A.R., Shrestha, N., Bower, R.L., Rosengren, R.J., Ashton, J.C.

    Published in Biochemical pharmacology (01-01-2021)
    “…[Display omitted] Cell based studies have suggested that the diabetes drug metformin may combine with the anaplastic lymphoma kinase receptor (ALK) inhibitor…”
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    Retinol Potentiates Acetaminophen-Induced Hepatotoxicity in the Mouse: Mechanistic Studies by Bray, B.J., Rosengren, R.J.

    Published in Toxicology and applied pharmacology (15-06-2001)
    “…This study was designed to elucidate the mechanism of retinol's potentiation of acetaminophen-induced hepatotoxicity. To accomplish this, the major…”
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    Acetaminophen elicits anti-estrogenic but not estrogenic responses in the immature mouse by Patel, R, Rosengren, R.J

    Published in Toxicology letters (31-05-2001)
    “…Acetaminophen is a widely used analgesic, which has exhibited evidence of estrogenic activity in estrogen-receptor positive human breast cancer cells. However,…”
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    Short term treatment with St. John's wort, hypericin or hyperforin fails to induce CYP450 isoforms in the Swiss Webster mouse by Bray, B.J., Brennan, N.J., Perry, N.B., Menkes, D.B., Rosengren, R.J.

    Published in Life sciences (1973) (01-02-2002)
    “…This investigation was designed to determine whether St. John's wort (SJW)(435 mg/kg/d), a readily available antidepressant, or its purported active…”
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    The effect of retinol on hepatic and renal drug-metabolising enzymes by Bray, B.J, Goodin, M.G, Inder, R.E, Rosengren, R.J

    Published in Food and chemical toxicology (2001)
    “…Retinol pretreatment (75 mg/kg/day, 4 days) potentiated paracetamol-induced hepatotoxicity in BALB/c mice (alanine aminotransferase (ALT) activity; 2510 ± 602…”
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