Search Results - "Rosenblum, Leonard"

Maternal hypothalamic-pituitary-adrenal axis response to foraging uncertainty: A model of individual vs. social allostasis and the "Superorganism Hypothesis" by Coplan, Jeremy D, Gupta, Nishant K, Karim, Asif, Rozenboym, Anna, Smith, Eric L P, Kral, John G, Rosenblum, Leonard A

“…Food insecurity is a major global contributor to developmental origins of adult disease. The allostatic load of maternal food uncertainty from variable…”
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Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques by KAUFMAN, Daniel, BANERJI, Mary Ann, SHORMAN, Igor, SMITH, Eric L. P, COPLAN, Jeremy D, ROSENBLUM, Leonard A, KRAL, John G

“…Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques Daniel Kaufman 1 2 , Mary Ann Banerji 2 3 , Igor Shorman 1…”
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Early-life stress, corpus callosum development, hippocampal volumetrics, and anxious behavior in male nonhuman primates by Jackowski, Andrea, Perera, Tarique D, Abdallah, Chadi G, Garrido, Griselda, Tang, Cheuk Y, Martinez, Jose, Mathew, Sanjay J, Gorman, Jack M, Rosenblum, Leonard A, Smith, Eric L.P, Dwork, Andrew J, Shungu, Dikoma C, Kaffman, Arie, Gelernter, Joel, Coplan, Jeremy D, Kaufman, Joan

“…Abstract Male bonnet monkeys ( Macaca radiata ) were subjected to the variable foraging demand (VFD) early stress paradigm as infants, MRI scans were completed…”
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Adult glucocorticoid receptor mRNA expression volatility in response to an acute stressor and juvenile CSF corticotropin-releasing factor: A pilot neurodevelopmental study by Syed, Shariful A., Smith, Eric L.P., Batuman, Olcay, Rosenblum, Leonard A., Owens, Michael J., Nemeroff, Charles B., Coplan, Jeremy D.

“…•The current pilot study in non-human primates has confirmed our hypothesis that juvenile CSF CRF, a marker of ELS, correlates significantly with a dynamic…”
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Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: A pilot study by Coplan, Jeremy D, Abdallah, Chadi G, Kaufman, Joan, Gelernter, Joel, Smith, Eric L.P, Perera, Tarique D, Dwork, Andrew J, Kaffman, Arie, Gorman, Jack M, Rosenblum, Leonard A, Owens, Michael J, Nemeroff, Charles B

“…Summary Recent studies have indicated a gene-by-environment interaction between serotonin transporter gene (5-HTTLPR) polymorphism and childhood abuse on…”
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The role of early life stress in development of the anterior limb of the internal capsule in nonhuman primates by Coplan, Jeremy D., Abdallah, Chadi G., Tang, Cheuk Y., Mathew, Sanjay J., Martinez, Jose, Hof, Patrick R., Smith, Eric L.P., Dwork, Andrew J., Perera, Tarique D., Pantol, Gustavo, Carpenter, David, Rosenblum, Leonard A., Shungu, Dikoma C., Gelernter, Joel, Kaffman, Arie, Jackowski, Andrea, Kaufman, Joan, Gorman, Jack M.

“…Deep brain stimulation (DBS) of the anterior limb of the internal capsule (ALIC) may be effective in treating depression. Parental verbal abuse has been linked…”
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Reduced left ventricular dimension and function following early life stress: A thrifty phenotype hypothesis engendering risk for mood and anxiety disorders by Coplan, Jeremy D., Rozenboym, Anna V., Fulton, Sasha L., Panthangi, Venkatesh, Tang, Jean, Thiramangalakdi, Lakshmi, Perera, Tarique D., Liu, Yang, Kamran, Haroon, Owens, Michael J., Nemeroff, Charles B., Rosenblum, Leonard A., Kral, John G., Salciccioli, Louis, Lazar, Jason

“…Early life stress (ELS) in macaques in the form of insecure maternal attachment putatively induces epigenetic adaptations resulting in a “thrifty phenotype”…”
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Correlations between Hippocampal Neurogenesis and Metabolic Indices in Adult Nonhuman Primates by Perera, Tarique D., Lu, Dunyue, Thirumangalakudi, Lakshmi, Smith, Eric L. P., Yaretskiy, Arkadiy, Rosenblum, Leonard A., Kral, John G., Coplan, Jeremy D.

“…Increased neurogenesis in feeding centers of the murine hypothalamus is associated with weight loss in diet-induced obese rodents (Kokoeva et al., 2005 and…”
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Effects of Acute Confinement Stress-induced Hypothalamic-pituitary Adrenal Axis Activation and Concomitant Peripheral and Central Transforming Growth Factor-β1 Measures in Nonhuman Primates by Coplan, Jeremy D., Gopinath, Srinath, Abdallah, Chadi G., Margolis, Jeffrey, Chen, Wei, Scharf, Bruce A., Rosenblum, Leonard A., Batuman, Olcay A., Smith, Eric L. P.

“…Transforming growth factor-β1 (TGF-β1) is a multifunctional cytokine with anti-inflammatory, immunosuppressive, and neuroprotective properties. The…”
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The Codes of Recognition by Goldberg, Louis J., Rosenblum, Leonard A.

“…This paper is divided into two parts. Part I focuses on the manner in which the components of the face recognition system work together so that a perceiver,…”
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Persistent Elevations of Cerebrospinal Fluid Concentrations of Corticotropin-Releasing Factor in Adult Nonhuman Primates Exposed to Early-Life Stressors: Implications for the Pathophysiology of Mood and Anxiety Disorders by Coplan, Jeremy D., Andrews, Michael W., Rosenblum, Leonard A., Owens, Michael J., Friedman, Steven, Gorman, Jack M., Nemeroff, Charles B.

“…There is increasing evidence for an important role of adverse early experience on the development of major psychiatric disorders in adulthood…”
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Early-life stress and neurometabolites of the hippocampus by Coplan, Jeremy D, Mathew, Sanjay J, Abdallah, Chadi G, Mao, Xiangling, Kral, John G, Smith, Eric L.P, Rosenblum, Leonard A, Perera, Tarique D, Dwork, Andrew J, Hof, Patrick R, Gorman, Jack M, Shungu, Dikoma C

“…Abstract We tested the hypothesis that early life stress would persistently compromise neuronal viability of the hippocampus of the grown nonhuman primate…”
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On the Genetic and Epigenetic Bases of Primate Signal Processing by Goldberg, Louis J., Rosenblum, Leonard A.

“…Four sequential, sub-processes are identified as the fundamental steps in the processing of signals by big-brained animals. These are, Detection of the signal,…”
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Energy expenditure in chow-fed female non-human primates of various weights by Rising, Russell, Signaevsky, Maxim, Rosenblum, Leonard A, Kral, John G, Lifshitz, Fima

“…Until now no technology has been available to study energy metabolism in monkeys. The objective of this study was to determine daily energy expenditures (EE)…”
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Variable foraging demand rearing: sustained elevations in cisternal cerebrospinal fluid corticotropin-releasing factor concentrations in adult primates by Coplan, Jeremy D, Smith, E.L.P, Altemus, Margaret, Scharf, Bruce A, Owens, Michael J, Nemeroff, Charles B, Gorman, Jack M, Rosenblum, Leonard A

“…Background: The authors previously reported elevated cerebrospinal fluid (CSF) corticotropin-releasing factor (CRF) concentrations in juvenile primates nursed…”
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Metabolic syndrome and neurometabolic asymmetry of hippocampus in adult bonnet monkeys by Coplan, Jeremy D, Abdallah, Chadi G, Mathew, Sanjay J, Shungu, Dikoma C, Mao, Xiangling, Smith, Eric L.P, Kaufman, Daniel, Gorman, Jack M, Owens, Michael J, Nemeroff, Charles B, Banerji, Mary Ann, Rosenblum, Leonard A, Kral, John G

“…Abstract Objective Obesity is associated with the insulin resistance metabolic syndrome, postulated to be mediated by stress-induced alterations within the…”
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Maternal-infant response to variable foraging demand in nonhuman primates: effects of timing of stressor on cerebrospinal fluid corticotropin-releasing factor and circulating glucocorticoid concentrations by Coplan, Jeremy D, Smith, Eric L P, Altemus, Margaret, Mathew, Sanjay J, Perera, Tarique, Kral, John G, Gorman, Jack M, Owens, Michael J, Nemeroff, Charles B, Rosenblum, Leonard A

“…The maternal stress response may vary as a function of infant developmental phase. Using a median split, 13 bonnet macaque (M. radiata) mother-infant dyads…”
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Decreased choline and creatine concentrations in centrum semiovale in patients with generalized anxiety disorder: Relationship to IQ and early trauma by Coplan, Jeremy D., Mathew, Sanjay J., Mao, Xiangling, Smith, Eric L.P., Hof, Patrick R., Coplan, Paul M., Rosenblum, Leonard A., Gorman, Jack M., Shungu, Dikoma C.

“…We have demonstrated, using proton magnetic resonance spectroscopy imaging ( 1H-MRSI), elevations of N-acetyl-aspartate/creatine (NAA/CR) in right dorsolateral…”
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A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressors by Mathew, Sanjay J., Shungu, Dikoma C., Mao, Xiangling, Smith, Eric L.P., Perera, Gerald M., Kegeles, Lawrence S., Perera, Tarique, Lisanby, Sarah H., Rosenblum, Leonard A., Gorman, Jack M., Coplan, Jeremy D.

“…Long-term behavioral, immunologic, and neurochemical alterations have been found in primates exposed to adverse early rearing. Bonnet macaque ( Macaca radiata)…”
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Early Appearance of the Metabolic Syndrome in Socially Reared Bonnet Macaques by Kaufman, Daniel, Smith, Eric L. P., Gohil, Baiju C., Banerji, MaryAnn, Coplan, Jeremy D., Kral, John G., Rosenblum, Leonard A.

“…Among 250 laboratory-born bonnet macaques living in social groups and maintained on commercial monkey chow, we measured weight, crown-rump length, sagittal…”
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