Search Results - "Rosenblum, Jeremy M."

Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice by Chu, Yaya, Nayyar, Gaurav, Jiang, Susiyan, Rosenblum, Jeremy M., Soon-Shiong, Patrick, Safrit, Jeffrey T, Lee, Dean A., Cairo, Mitchell S.

“…BackgroundChildren with recurrent and/or metastatic osteosarcoma (OS), neuroblastoma (NB) and glioblastoma multiforme (GBM) have a dismal event-free survival…”
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Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning "Two Keys" simultaneously by Luo, Wen, Hoang, Hai, Miller, Katherine E, Zhu, Hongwen, Xu, Serena, Mo, Xiaokui, Garfinkle, Elizabeth A R, Costello, Heather, Wijeratne, Saranga, Chemnitz, Wiebke, Gandhi, Ronan, Liao, Yanling, Ayello, Janet, Gardenswartz, Aliza, Rosenblum, Jeremy M, Cassady, Kevin A, Mardis, Elaine R, Lee, Dean A, Cripe, Timothy P, Cairo, Mitchell S

“…Macrophages play important roles in phagocytosing tumor cells. However, tumors escape macrophage phagocytosis in part through the expression of anti-phagocytic…”
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Circumventing resistance within the Ewing sarcoma microenvironment by combinatorial innate immunotherapy by Luo, Wen, Hoang, Hai, Zhu, Hongwen, Miller, Katherine, Mo, Xiaokui, Eguchi, Shiori, Tian, Meijuan, Liao, Yanling, Ayello, Janet, Rosenblum, Jeremy M, Marcondes, Mario, Currier, Mark, Mardis, Elaine, Cripe, Timothy, Lee, Dean, Cairo, Mitchell S

“…BackgroundPediatric patients with recurrent/metastatic Ewing sarcoma (ES) have a dismal 5-year survival. Novel therapeutic approaches are desperately needed…”
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Novel cytokine–antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma by Chu, Yaya, Nayyar, Gaurav, Kham Su, Nang, Rosenblum, Jeremy M, Soon-Shiong, Patrick, Lee, John, Safrit, Jeffrey T, Barth, Matthew, Lee, Dean, Cairo, Mitchell S

“…BackgroundThe prognosis of patients with relapsed or progressive B cell (CD20+) non-Hodgkin’s lymphoma (B-NHL), including Burkitt lymphoma (BL), is dismal due…”
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Predictive properties of DNA methylation patterns in primary tumor samples for osteosarcoma relapse status by Rosenblum, Jeremy M, Wijetunga, N Ari, Fazzari, Melissa J, Krailo, Mark, Barkauskas, Donald A, Gorlick, Richard, Greally, John M

“…Osteosarcoma is the most common primary malignant bone tumor in children. Validated biological markers for disease prognosis available at diagnosis are…”
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Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board by Gupta, Ajay, Riedel, Richard F, Shah, Chirag, Borinstein, Scott C, Isakoff, Michael S, Chugh, Rashmi, Rosenblum, Jeremy M, Murphy, Erin S, Campbell, Shauna R, Albert, Catherine M, Zahler, Stacey, Thomas, Stefanie M, Trucco, Matteo

“…Ewing sarcoma (ES) is a malignant tumor of bone and soft tissue that most often occurs in adolescents and young adults. Despite an international coordinated…”
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Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board by Gupta, Ajay, Dietz, Matthew S., Riedel, Richard F., Dhir, Aditi, Borinstein, Scott C., Isakoff, Michael S., Aye, Jamie M., Rainusso, Nino, Armstrong, Amy E., DuBois, Steven G., Wagner, Lars M., Rosenblum, Jeremy M., Cohen‐Gogo, Sarah, Albert, Catherine M., Zahler, Stacey, Chugh, Rashmi, Trucco, Matteo

“…Ewing sarcoma (ES) is a malignant tumor of bone and soft tissue that most often occurs in children, adolescents, and young adults. Debate and controversy…”
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Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma by Luo, Wen, Xu, Changxin, Phillips, Sarah, Gardenswartz, Aliza, Rosenblum, Jeremy M., Ayello, Janet, Lessnick, Stephen L., Hao, Huai-Xiang, Cairo, Mitchell S.

“…Ewing sarcoma (ES) is a malignant pediatric bone and soft tissue tumor. Patients with metastatic ES have a dismal outcome which has not been improved in…”
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Combinatorial immunotherapy of anti-MCAM CAR-modified expanded natural killer cells and NKTR-255 against neuroblastoma by Luo, Wen, Gardenswartz, Aliza, Hoang, Hai, Chu, Yaya, Tian, Meijuan, Liao, Yanling, Ayello, Janet, Rosenblum, Jeremy M., Mo, Xiaokui, Marcondes, A. Mario, Overwijk, Willem W., Cripe, Timothy P., Lee, Dean A., Cairo, Mitchell S.

“…Pediatric patients with recurrent metastatic neuroblastoma (NB) have a dismal 5-year survival. Novel therapeutic approaches are urgently needed. The melanoma…”
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Abstract 6594: Targeting Ewing sarcoma and osteosarcoma with anti-MCAM chimeric antigen receptor modified NK cells by Gardenswartz, Aliza, Luo, Wen, Rosenblum, Jeremy M., Ayello, Janet, Cairo, Mitchell S.

“…Abstract Ewing sarcoma and osteosarcoma are the two most common pediatric malignant bone tumors. Patients who present with metastatic disease or relapse have a…”
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