Search Results - "Rosenberry, T. L"

3D Structure of Torpedo californica Acetylcholinesterase Complexed with Huprine X at 2.1 Å Resolution:  Kinetic and Molecular Dynamic Correlates by Dvir, H, Wong, D. M, Harel, M, Barril, X, Orozco, M, Luque, F. J, Muñoz-Torrero, D, Camps, P, Rosenberry, T. L, Silman, I, Sussman, J. L

“…Huprine X is a novel acetylcholinesterase (AChE) inhibitor, with one of the highest affinities reported for a reversible inhibitor. It is a synthetic hybrid…”
Get full text

Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors by HAREL, MICHAL, KRYGER, GITAY, ROSENBERRY, TERRONE L., MALLENDER, WILLIAM D., LEWIS, TERENCE, FLETCHER, RODNEY J., GUSS, J. MITCHELL, SILMAN, ISRAEL, SUSSMAN, JOEL L.

“…We have crystallized Drosophila melanogaster acetylcholinesterase and solved the structure of the native enzyme and of its complexes with two potent reversible…”
Get full text

Lipid analysis of the glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase. Palmitoylation of inositol results in resistance to phosphatidylinositol-specific phospholipase C by Roberts, W L, Myher, J J, Kuksis, A, Low, M G, Rosenberry, T L

“…The glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase (EC 3.1.1.7) contains a novel inositol phospholipid which in this and…”
Get full text

Structural characterization of the glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase by fast atom bombardment mass spectrometry by Roberts, W L, Santikarn, S, Reinhold, V N, Rosenberry, T L

“…The glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase (EC 3.1.1.7) is composed of a glycan linked through a glucosamine…”
Get full text

Characterization of putative glycoinositol phospholipid anchor precursors in mammalian cells. Localization of phosphoethanolamine by HIROSE, S, PRINCE, G. M, SEVLEVER, D, RAVI, L, ROSENBERRY, T. L, UEDA, E, MEDOF, M. E

“…A number of mammalian cell surface proteins are anchored by glycoinositol phospholipid (GPI) structures that are preassembled and transferred to them in the…”
Get full text

Isolation and characterization of acetylcholinesterase from Drosophila by Gnagey, A L, Forte, M, Rosenberry, T L

“…The purification and characterization of acetylcholinesterase from heads of the fruit fly Drosophila are described. Sequential extraction procedures indicated…”
Get full text

Structural basis for variations in the sensitivity of human decay accelerating factor to phosphatidylinositol-specific phospholipase C cleavage [published erratum appears in J Immunol 1990 May 15;144(10):4072] by Walter, EI, Roberts, WL, Rosenberry, TL, Ratnoff, WD, Medof, ME

“…Human decay-accelerating factor (DAF) proteins expressed on E and nucleated cells differ in their susceptibility to phosphatidylinositol (PI)-specific…”
Get full text

Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues by Inestrosa, N.C., Roberts, W.L., Marshall, T.L., Rosenberry, T.L.

“…Acetylcholinesterase extracted with Triton X-100 from bovine brain caudate nuclei was purified by affinity chromatography to apparent homogeneity. The purified…”
Get full text

Glycan components in the glycoinositol phospholipid anchor of human erythrocyte acetylcholinesterase. Novel fragments produced by trifluoroacetic acid by DEEG, M. A, HUMPHREY, D. R, SHUN HUA YANG, FERGUSON, T. R, REINHOLD, V. N, ROSENBERRY, T. L

“…Inositol glycans were prepared from reductively radiomethylated human erythrocyte acetylcholinesterase by sequential treatment with Proteinase K, methanolic…”
Get full text

Structure of human erythrocyte acetylcholinesterase. Characterization of intersubunit disulfide bonding and detergent interaction by Rosenberry, T L, Scoggin, D M

“…A large scale purification procedure for human erythrocyte acetylcholinesterase that involved affinity chromatography on an acridinium resin permitted the…”
Get full text

Location of Seven Post-translational Modifications in Rabbit Elongation Factor 1α Including Dimethyllysine, Trimethyllysine, and Glycerylphosphorylethanolamine by Dever, T.E., Costello, C.E., Owens, C.L., Rosenberry, T.L., Merrick, W.C.

“…Amino acid sequencing of a large number of chemical and enzymatic cleavage products of elongation factor 1α purified from rabbit reticulocyte has identified…”
Get full text

Mannosamine inhibits the synthesis of putative glycoinositol phospholipid anchor precursors in mammalian cells without incorporating into an accumulated intermediate by Sevlever, D., Rosenberry, T.L.

“…Mannosamine (ManN) has been reported to inhibit the formation of Man alpha-1,2Man linkages and to prevent the anchoring of membrane proteins by glycoinositol…”
Get full text

Glycoinositol phospholipid anchor-defective K562 mutants with biochemical lesions distinct from those in Thy-1- murine lymphoma mutants by MOHNEY, R. P, KNEZ, J. J, RAVI, L, SEVLEVER, D, ROSENBERRY, T. L, HIROSE, S, MEDOF, M. E

“…Deficient expression of glycoinositol phospholipid (GPI)-anchored surface proteins has been linked to six different genetic defects in Thy-1- murine lymphoma…”
Get full text

Brain cDNA Clone for Human Cholinesterase by McTiernan, Charles, Adkins, Steve, Chatonnet, Arnaud, Vaughan, Theresa A., Bartels, Cynthia F., Kott, Matthew, Rosenberry, Terrone L., La Du, Bert N., Lockridge, Oksana

“…A cDNA library from human basal ganglia was screened with oligonucleotide probes corresponding to portions of the amino acid sequence of human serum…”
Get full text

Bovine brain acetylcholinesterase primary sequence involved in intersubunit disulfide linkages by Roberts, W L, Doctor, B P, Foster, J D, Rosenberry, T L

“…Three distinct classes of membrane-bound acetylcholinesterases (AChEs) have been identified. A12 AChE is composed of 12 catalytic subunits that are linked to…”
Get full text

Decay accelerating factor of complement is anchored to cells by a C-terminal glycolipid by Medof, M. Edward, Walter, Elizabeth I, Roberts, William L, Haas, Robert, Rosenberry, Terrone L

“…Membrane-associated decay accelerating factor (DAF) of human erythrocytes (Ehu) was analyzed for a C-terminal glycolipid anchoring structure. Automated amino…”
Get full text

A candidate mammalian glycoinositol phospholipid precursor containing three phosphoethanolamines by Ueda, E., Sevlever, D., Prince, G.M., Rosenberry, T.L., Hirose, S., Medof, M.E.

“…The glycoinositol phospholipid (GPI) anchors of mammalian proteins contain linear ethanolamine (EthN)-P-6ManManManGlcN glycan sequences that bear additional…”
Get full text

Biosynthetic incorporation of [3H]ethanolamine into protein synthesis elongation factor 1α reveals a new post-translational protein modification by Rosenberry, T L, Krall, J A, Dever, T E, Haas, R, Louvard, D, Merrick, W C

“…Biosynthetic incorporation of [3H]ethanolamine into proteins was assessed in the human erythroleukemia cell line K562. A single predominant labeled protein of…”
Get full text

Thioflavin T Is a Fluorescent Probe of the Acetylcholinesterase Peripheral Site That Reveals Conformational Interactions between the Peripheral and Acylation Sites by De Ferrari, Giancarlo V., Mallender, William D., Inestrosa, Nibaldo C., Rosenberry, Terrone L.

“…Three-dimensional structures of acetylcholinesterase (AChE) reveal a narrow and deep active site gorge with two sites of ligand binding, an acylation site at…”
Get full text

Acetylthiocholine Binds to Asp74 at the Peripheral Site of Human Acetylcholinesterase as the First Step in the Catalytic Pathway by Mallender, William D, Szegletes, Tivadar, Rosenberry, Terrone L

“…Studies of ligand binding to acetylcholinesterase (AChE) have demonstrated two sites of interaction. An acyl−enzyme intermediate is formed at the acylation…”
Get full text