Search Results - "Rosenberg, Mark F"

Structure and function of the human breast cancer resistance protein (BCRP/ABCG2) by Ni, Zhanglin, Bikadi, Zsolt, Rosenberg, Mark F, Mao, Qingcheng

“…The human breast cancer resistance protein (BCRP/ABCG2) is the second member of the G subfamily of the large ATP-binding cassette (ABC) transporter…”
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Bacterial DNA segregation dynamics mediated by the polymerizing protein ParF by Barillà, Daniela, Rosenberg, Mark F, Nobbmann, Ulf, Hayes, Finbarr

“…Prokaryotic DNA segregation most commonly involves members of the Walker‐type ParA superfamily. Here we show that the ParF partition protein specified by the…”
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Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding by Rosenberg, Mark F, Kamis, Alhaji Bukar, Callaghan, Richard, Higgins, Christopher F, Ford, Robert C

“…P-glycoprotein is an ATP-binding cassette transporter that is associated with multidrug resistance and the failure of chemotherapy in human patients. We have…”
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Purification and Crystallization of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Rosenberg, Mark F., Kamis, Alhaji Bukar, Aleksandrov, Luba A., Ford, Robert C., Riordan, John R.

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein that is mutated in patients suffering from cystic fibrosis. Here we report…”
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The Human Breast Cancer Resistance Protein (BCRP/ABCG2) Shows Conformational Changes with Mitoxantrone by Rosenberg, Mark F., Bikadi, Zsolt, Chan, Janice, Liu, Xiaoping, Ni, Zhanglin, Cai, Xiaokun, Ford, Robert C., Mao, Qingcheng

“…BCRP/ABCG2 mediates efflux of drugs and xenobiotics. BCRP was expressed in Pichia pastoris, purified to > 90% homogeneity, and subjected to two-dimensional…”
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The cystic fibrosis transmembrane conductance regulator (CFTR): three-dimensional structure and localization of a channel gate by Rosenberg, Mark F, O'Ryan, Liam P, Hughes, Guy, Zhao, Zhefeng, Aleksandrov, Luba A, Riordan, John R, Ford, Robert C

“…Cystic fibrosis affects about 1 in 2500 live births and involves loss of transmembrane chloride flux due to a lack of a membrane protein channel termed the…”
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Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport by Ni, Zhanglin, Bikadi, Zsolt, Cai, Xiaokun, Rosenberg, Mark F, Mao, Qingcheng

“…The human breast cancer resistance protein (BCRP/ABCG2) mediates efflux of drugs and xenobiotics. In this study, we investigated the role of polar residues…”
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Identification of Proline Residues in or near the Transmembrane Helices of the Human Breast Cancer Resistance Protein (BCRP/ABCG2) That Are Important for Transport Activity and Substrate Specificity by Ni, Zhanglin, Bikadi, Zsolt, Shuster, Diana L, Zhao, Chunsheng, Rosenberg, Mark F, Mao, Qingcheng

“…The human breast cancer resistance protein (BCRP/ABCG2) confers multidrug resistance and mediates the active efflux of drugs and xenobiotics. BCRP contains one…”
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Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state by Rosenberg, Mark F, Callaghan, Richard, Modok, Szabolcs, Higgins, Christopher F, Ford, Robert C

“…Multidrug resistance of cancer cells and pathogens is a serious clinical problem. A major factor contributing to drug resistance in cancer is the…”
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Role of basic residues within or near the predicted transmembrane helix 2 of the human breast cancer resistance protein in drug transport by Cai, Xiaokun, Bikadi, Zsolt, Ni, Zhanglin, Lee, Eun-Woo, Wang, Honggang, Rosenberg, Mark F, Mao, Qingcheng

“…The human breast cancer resistance protein (BCRP/ABCG2) mediates efflux of drugs and xenobiotics out of cells. In this study, we investigated the role of five…”
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Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation by Rosenberg, Mark F., Bikadi, Zsolt, Hazai, Eszter, Starborg, Tobias, Kelley, Lawrence, Chayen, Naomi E., Ford, Robert C., Mao, Qingcheng

“…ABCG2 is an efflux drug transporter that plays an important role in drug resistance and drug disposition. In this study, the first three‐dimensional structure…”
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Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle by Rosenberg, Mark F., Velarde, Giles, Ford, Robert C., Martin, Catherine, Berridge, Georgina, Kerr, Ian D., Callaghan, Richard, Schmidlin, Andreas, Wooding, Carol, Linton, Kenneth J., Higgins, Christopher F.

“…P‐glycoprotein (P‐gp) is an ABC (ATP‐binding cassette) transporter, which hydrolyses ATP and extrudes cytotoxic drugs from mammalian cells. P‐gp consists of…”
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CFTR three-dimensional structure by Ford, Robert C, Birtley, James, Rosenberg, Mark F, Zhang, Liang

“…CFTR is a member of the ATP-binding cassette family of membrane proteins. This is one of the best characterised membrane protein families in terms of structure…”
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Structure of a human multidrug transporter in an inward-facing conformation by Rosenberg, Mark F., Oleschuk, Curtis J., Wu, Peng, Mao, Qingcheng, Deeley, Roger G., Cole, Susan P.C., Ford, Robert C.

“…Multidrug resistance protein 1 (ABCC1) is a member of the ‘C’ class of ATP-binding cassette transporters, which can give rise to resistance to chemotherapy via…”
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Structure of the Multidrug Resistance P-glycoprotein to 2.5 nm Resolution Determined by Electron Microscopy and Image Analysis by Rosenberg, M F, Callaghan, R, Ford, R C, Higgins, C F

“…P-glycoprotein (P-gp) is a member of the ATP binding cassette superfamily of active transporters and can confer multidrug resistance on cells and tumors by…”
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The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Rosenberg, Mark F., O'Ryan, Liam P., Hughes, Guy, Zhao, Zhefeng, Aleksandrov, Luba A., Riordan, John R., Ford, Robert C.

“…Cystic fibrosis affects about 1 in 2500 live births and involves loss of transmembrane chloride flux due to a lack of a membrane protein channel termed the…”
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Three-dimensional Structure of Transporter Associated with Antigen Processing (TAP) Obtained by Single Particle Image Analysis by Velarde, Giles, Ford, Robert C., Rosenberg, Mark F., Powis, Simon J.

“…The transporter associated with antigen processing (TAP) is an ATP binding cassette transporter responsible for peptide translocation into the lumen of the…”
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Three-dimensional Structure of P-glycoprotein by Rosenberg, Mark F., Callaghan, Richard, Modok, Szabolcs, Higgins, Christopher F., Ford, Robert C.

“…Multidrug resistance of cancer cells and pathogens is a serious clinical problem. A major factor contributing to drug resistance in cancer is the…”
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The Structure of the Multidrug Resistance Protein 1 (MRP1/ABCC1) by Rosenberg, Mark F., Mao, Qingcheng, Holzenburg, Andreas, Ford, Robert C., Deeley, Roger G., Cole, Susan P.C.

“…Multidrug resistance protein 1 (MRP1/ABCC1) is an ATP-binding cassette (ABC) polytopic membrane transporter of considerable clinical importance that confers…”
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Three-Dimensional Structure of Herpes Simplex Virus Type 1 Glycoprotein D at 2.4-Nanometer Resolution by Pilling, A, Rosenberg, M F, Willis, S H, Jäger, J, Cohen, G H, Eisenberg, R J, Meredith, D M, Holzenburg, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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