Search Results - "Rosenberg, Evan C."
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Don’t Give Me Lip: A Role for Lipid-Accumulated Reactive Astrocytes in Temporal Lobe Epilepsy
Published in Epilepsy currents (01-09-2023)“…Lipid-Accumulated Reactive Astrocytes Promote Disease Progression in Epilepsy Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P,…”
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Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain
Published in Neurobiology of disease (01-08-2018)“…Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits…”
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Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open‐label clinical study with cannabidiol
Published in Epilepsia (Copenhagen) (01-08-2017)“…Summary Recent clinical trials indicate that cannabidiol (CBD) may reduce seizure frequency in pediatric patients with certain forms of treatment‐resistant…”
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Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection
Published in Epilepsy & behavior (01-05-2017)“…Abstract The isolation and identification of the discrete plant cannabinoids in marijuana revived interest in analyzing historical therapeutic claims made for…”
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Cannabinoids and Epilepsy
Published in Neurotherapeutics (01-10-2015)“…Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest…”
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Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity
Published in Neuron (Cambridge, Mass.) (19-04-2023)“…Cannabidiol (CBD), a non-euphoric component of cannabis, reduces seizures in multiple forms of pediatric epilepsies, but the mechanism(s) of anti-seizure…”
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Lestaurtinib (CEP-701) attenuates “second hit” kainic acid-induced seizures following early life hypoxic seizures
Published in Epilepsy research (01-05-2014)“…Highlights • Hypoxic seizures transiently activate the tropomyosin-related kinase receptor B (TrkB). • Lestaurtinib (CEP-701) attenuates seizure-induced TrkB…”
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