Search Results - "Rosen, Laura G"

Molecular and neuronal plasticity mechanisms in the amygdala-prefrontal cortical circuit: implications for opiate addiction memory formation by Rosen, Laura G, Sun, Ninglei, Rushlow, Walter, Laviolette, Steven R

“…The persistence of associative memories linked to the rewarding properties of drugs of abuse is a core underlying feature of the addiction process. Opiate…”
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Effects of Patterned Sound Deprivation on Short- and Long-Term Plasticity in the Rat Thalamocortical Auditory System In Vivo by Dringenberg, Hans C., Rodier, Simon G., Rosen, Laura G., Soutar, Chloe N.

“…Postnatal sensory experience plays a significant role in the maturation and synaptic stabilization of sensory cortices, such as the primary auditory cortex…”
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Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations in the Prefrontal Cortex by Renard, Justine, Rosen, Laura G, Loureiro, Michael, De Oliveira, Cleusa, Schmid, Susanne, Rushlow, Walter J, Laviolette, Steven R

“…Considerable evidence suggests that adolescent exposure to delta-9-tetrahydrocanabinol (THC), the psychoactive component in marijuana, increases the risk of…”
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Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway by Renard, Justine, Loureiro, Michael, Rosen, Laura G, Zunder, Jordan, de Oliveira, Cleusa, Schmid, Susanne, Rushlow, Walter J, Laviolette, Steven R

“…Schizophrenia-related psychosis is associated with disturbances in mesolimbic dopamine (DA) transmission, characterized by hyperdopaminergic activity in the…”
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Cannabinoid Transmission in the Hippocampus Activates Nucleus Accumbens Neurons and Modulates Reward and Aversion-Related Emotional Salience by Loureiro, Michael, Kramar, Cecilia, Renard, Justine, Rosen, Laura G, Laviolette, Steven R

“…Abstract Background Cannabinoid receptor transmission strongly influences emotional processing, and disturbances in cannabinoid signaling are associated with…”
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Adolescent Nicotine Exposure Induces Dysregulation of Mesocorticolimbic Activity States and Depressive and Anxiety-like Prefrontal Cortical Molecular Phenotypes Persisting into Adulthood by Jobson, Christina L M, Renard, Justine, Szkudlarek, Hanna, Rosen, Laura G, Pereira, Brian, Wright, Daniel J, Rushlow, Walter, Laviolette, Steven R

“…Abstract Considerable evidence demonstrates strong comorbidity between nicotine dependence and mood and anxiety disorders. Nevertheless, the neurobiological…”
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Opiate exposure state controls dopamine D3 receptor and cdk5/calcineurin signaling in the basolateral amygdala during reward and withdrawal aversion memory formation by Rosen, Laura G., Rushlow, Walter J., Laviolette, Steven R.

“…The dopamine (DA) D3 receptor (D3R) is highly expressed in the basolateral nucleus of the amygdala (BLA), a neural region critical for processing…”
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Opiate Exposure State Controls a D2-CaMKIIα-Dependent Memory Switch in the Amygdala-Prefrontal Cortical Circuit by Rosen, Laura G, Zunder, Jordan, Renard, Justine, Fu, Jennifer, Rushlow, Walter, Laviolette, Steven R

“…The mammalian basolateral amygdala (BLA) and medial prefrontal cortex (mPFC) comprise a functionally interconnected circuit that is critical for processing…”
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NMDA Receptor Blockade in the Prelimbic Cortex Activates the Mesolimbic System and Dopamine-Dependent Opiate Reward Signaling by Tan, Huibing, Rosen, Laura G., Ng, Garye A., Rushlow, Walter J., Laviolette, Steven R.

“…Rationale N-Methyl- d -aspartate (NMDA) receptors in the medial prefrontal cortex (mPFC) are involved in opiate reward processing and modulate sub-cortical…”
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Opiate exposure and withdrawal induces a molecular memory switch in the basolateral amygdala between ERK1/2 and CaMKIIα-dependent signaling substrates by Lyons, Danika, de Jaeger, Xavier, Rosen, Laura G, Ahmad, Tasha, Lauzon, Nicole M, Zunder, Jordan, Coolen, Lique M, Rushlow, Walter, Laviolette, Steven R

“…Opiate reward memories are powerful triggers for compulsive opiate-seeking behaviors. The basolateral amygdala (BLA) is an important structure for the…”
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Occlusion of low-frequency-induced, heterosynaptic long-term potentiation in the rat hippocampus in vivo following spatial training by Habib, Diala, Tsui, Claudia K Y, Rosen, Laura G, Dringenberg, Hans C

“…Recent work has shown that some low-frequency stimulation (LFS) protocols can induce long-term potentiation (LTP) at hippocampal synapses. As LFS mimics…”
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Opiate Exposure State Controls a D2-CaMKII[alpha]-Dependent Memory Switch in the Amygdala-Prefrontal Cortical Circuit by Rosen, Laura G, Zunder, Jordan, Renard, Justine, Fu, Jennifer, Rushlow, Walter, Laviolette, Steven R

“…The mammalian basolateral amygdala (BLA) and medial prefrontal cortex (mPFC) comprise a functionally interconnected circuit that is critical for processing…”
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Opiate-Induced Neuroplastic Alterations to Dopamine Signaling in the Basolateral Amygdala-Prefrontal Cortical Pathway by Rosen, Laura G

“…Opiate addiction is a chronic disorder with high rates of relapse. The failure to maintain sobriety after prolonged abstinence is believed to be due in part to…”
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