Search Results - "Rosen, Eliot M."

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  1. 1

    DIM (3,3′-diindolylmethane) confers protection against ionizing radiation by a unique mechanism by Fan, Saijun, Meng, Qinghui, Xu, Jiaying, Jiao, Yang, Zhao, Lin, Zhang, Xiaodong, Sarkar, Fazlul H., Brown, Milton L., Dritschilo, Anatoly, Rosen, Eliot M.

    “…DIM (3,3′-diindolylmethane), a small molecule compound, is a proposed cancer preventive agent that can be safely administered to humans in repeated doses. We…”
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  2. 2

    Targeting the BRCA1/2 tumor suppressors by Rosen, Eliot M, Pishvaian, Michael J

    Published in Current drug targets (01-01-2014)
    “…The breast cancer susceptibility genes BRCA1 and BRCA2 are classic tumor suppressor genes that exhibit an autosomal dominant pattern of inheritance with high…”
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  3. 3

    Transcriptional Regulation of the Base Excision Repair Pathway by BRCA1 by Saha, Tapas, Rih, Jeong Keun, Roy, Rabindra, Ballal, Rahul, Rosen, Eliot M.

    Published in The Journal of biological chemistry (18-06-2010)
    “…Inactivation of the breast cancer susceptibility gene BRCA1 plays a significant role in the development of a subset of breast cancers, although the major tumor…”
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  4. 4

    BRCA1 down-regulates cellular levels of reactive oxygen species by Saha, Tapas, Rih, Jeong Keun, Rosen, Eliot M.

    Published in FEBS letters (06-05-2009)
    “…Previous studies have shown that the breast cancer suppressor BRCA1 stimulates antioxidant gene expression and protects cells against oxidative stress. To…”
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  5. 5

    Interlaced X-Ray Microplanar Beams: A Radiosurgery Approach with Clinical Potential by Dilmanian, F. Avraham, Zhong, Zhong, Bacarian, Tigran, Benveniste, Helene, Romanelli, Pantaleo, Wang, Ruiliang, Welwart, Jeremy, Yuasa, Tetsuya, Rosen, Eliot M., Anschel, David J.

    “…Studies have shown that x-rays delivered as arrays of parallel microplanar beams (microbeams), 25- to 90-μm thick and spaced 100-300 μm on-center,…”
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  6. 6

    BRCA1 Localization to the Telomere and Its Loss from the Telomere in Response to DNA Damage by Ballal, Rahul D., Saha, Tapas, Fan, Saijun, Haddad, Bassam R., Rosen, Eliot M.

    Published in The Journal of biological chemistry (25-12-2009)
    “…BRCA1, a tumor suppressor, participates in DNA damage signaling and repair. Previously, we showed that BRCA1 overexpression caused inhibition of telomerase…”
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  7. 7

    Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor by Reznik, Thomas E, Sang, Yingying, Ma, Yongxian, Abounader, Roger, Rosen, Eliot M, Xia, Shuli, Laterra, John

    Published in Molecular cancer research (01-01-2008)
    “…The mechanisms and biological implications of coordinated receptor tyrosine kinase coactivation remain poorly appreciated. Epidermal growth factor receptor…”
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  8. 8

    BRCA1 induces antioxidant gene expression and resistance to oxidative stress by INSOO BAE, SAIJUN FAN, QINGHUI MENG, JEONG KEUN RIH, HEE JONG KIM, HYO JIN KANG, JINGWEN XU, GOLDBERG, Itzhak D, JAISWAL, Anil K, ROSEN, Eliot M

    Published in Cancer research (Chicago, Ill.) (01-11-2004)
    “…Mutations of the breast cancer susceptibility gene 1 (BRCA1), a tumor suppressor, confer an increased risk for breast, ovarian, and prostate cancers. To…”
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  9. 9

    BRCA1 gene in breast cancer by Rosen, Eliot M., Fan, Saijun, Pestell, Richard G., Goldberg, Itzhak D.

    Published in Journal of cellular physiology (01-07-2003)
    “…The BRCA1 gene was identified and cloned in 1994 based its linkage to early onset breast cancer and breast‐ovarian cancer syndromes in women. While inherited…”
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  10. 10

    BRCA1 Inhibits Membrane Estrogen and Growth Factor Receptor Signaling to Cell Proliferation in Breast Cancer by Razandi, Mahnaz, Pedram, Ali, Rosen, Eliot M., Levin, Ellis R.

    Published in Molecular and Cellular Biology (01-07-2004)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  11. 11

    Role of Src Signal Transduction Pathways in Scatter Factor-mediated Cellular Protection by Fan, Saijun, Meng, Qinghui, Laterra, John J., Rosen, Eliot M.

    Published in The Journal of biological chemistry (20-03-2009)
    “…Scatter factor (SF) (hepatocyte growth factor) is a pleiotrophic cytokine that accumulates in tumors, where it may induce invasion, angiogenesis, and…”
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  12. 12

    BRCA1 regulation of base excision repair pathway by Saha, Tapas, Smulson, Mark, Rosen, Eliot M.

    Published in Cell cycle (Georgetown, Tex.) (01-07-2010)
    “…This feature item briefly reviews the relation of the tumor suppressor function of BRCA1 with DNA damage and repair. The main focus of this article is on the…”
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  13. 13

    The Breast Cancer Susceptibility Gene BRCA1 Regulates Progesterone Receptor Signaling in Mammary Epithelial Cells by Ma, Yongxian, Katiyar, Pragati, Jones, Laundette P, Fan, Saijun, Zhang, Yiyu, Furth, Priscilla A, Rosen, Eliot M

    Published in Molecular endocrinology (Baltimore, Md.) (01-01-2006)
    “…The progesterone receptor (PR) plays roles in normal mammary development and breast cancer formation, where it may exert both stimulatory and inhibitory…”
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  14. 14

    BRCA1 Interaction with Human Papillomavirus Oncoproteins by Zhang, Yiyu, Fan, Saijun, Meng, Qinghui, Ma, Yongxian, Katiyar, Pragati, Schlegel, Richard, Rosen, Eliot M.

    Published in The Journal of biological chemistry (30-09-2005)
    “…Previously, we reported that BRCA1 strongly represses the transcriptional activity of estrogen receptor-α (ER-α) in human breast and prostate cancer cells but…”
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  15. 15

    BRCA1 regulates follistatin function in ovarian cancer and human ovarian surface epithelial cells by Karve, Tejaswita M, Preet, Anju, Sneed, Rosie, Salamanca, Clara, Li, Xin, Xu, Jingwen, Kumar, Deepak, Rosen, Eliot M, Saha, Tapas

    Published in PloS one (01-06-2012)
    “…Follistatin (FST), a folliculogenesis regulating protein, is found in relatively high concentrations in female ovarian tissues. FST acts as an antagonist to…”
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  16. 16

    In vivo targeting of SF/HGF and c‐met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis by Abounader, Roger, Lal, Bachchu, Luddy, Carey, Koe, Gary, Davidson, Beverly, Rosen, Eliot M., Laterra, John

    Published in The FASEB journal (01-01-2002)
    “…The multifunctional growth factor scatter factor/hepatocyte growth factor (SF/HGF) and its receptor c‐met have been implicated in the genesis, malignant…”
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  17. 17

    Ribotoxic Stress Sensitizes Glioblastoma Cells to Death Receptor–Induced Apoptosis: Requirements for c-Jun NH2-Terminal Kinase and Bim by Xia, Shuli, Li, Yang, Rosen, Eliot M, Laterra, John

    Published in Molecular cancer research (01-08-2007)
    “…A prominent feature of glioblastoma is its resistance to death receptor–mediated apoptosis. In this study, we explored the possibility of modulating death…”
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  18. 18

    BRCA1 Modulates Xenobiotic Stress-inducible Gene Expression by Interacting with ARNT in Human Breast Cancer Cells by Kang, Hyo Jin, Kim, Hee Jeong, Kim, Sang Keun, Barouki, Robert, Cho, Chi-Heum, Khanna, Kum Kum, Rosen, Eliot M., Bae, Insoo

    Published in The Journal of biological chemistry (26-05-2006)
    “…Previously, we have reported that BRCA1 regulates the expression of various classes of genes, including genes involved in xenobiotic stress responses (Bae, I.,…”
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  19. 19

    New approaches to radiation protection by Rosen, Eliot M, Day, Regina, Singh, Vijay K

    Published in Frontiers in oncology (20-01-2015)
    “…Radioprotectors are compounds that protect against radiation injury when given prior to radiation exposure. Mitigators can protect against radiation injury…”
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  20. 20

    Murine EMT-6 Carcinoma: High Therapeutic Efficacy of Microbeam Radiation Therapy by Dilmanian, F. Avraham, Morris, Gerard M., Zhong, Nan, Bacarian, Tigran, Hainfeld, James F., Kalef-Ezra, John, Brewington, Laura J., Tammam, Jennifer, Rosen, Eliot M.

    Published in Radiation research (01-05-2003)
    “…Dilmanian, F. A., Morris, G. M., Zhong, N., Bacarian, T., Hainfeld, J. F., Kalef-Ezra, J., Brewington, L. J., Tammam, J. and Rosen, E. M. Murine EMT-6…”
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