Search Results - "Rosemberg, Denis Broock"
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A comparison of the light/dark and novel tank tests in zebrafish
Published in Behaviour (2012)“…The recent introduction of tasks to assess the behavior of zebrafish in novel and/or aversive environments has spurred great interest, prompting attempts to…”
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Trichomonas vaginalis nucleoside triphosphate diphosphohydrolase and ecto-5′-nucleotidase activities are inhibited by lycorine and candimine
Published in Parasitology international (01-06-2010)“…Abstract Drug discovery from plants plays an important role in the pharmaceutical therapy field and the alkaloids lycorine and candimine are candidates for…”
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Different effects of caffeine on behavioral neurophenotypes of two zebrafish populations
Published in Pharmacology, biochemistry and behavior (01-02-2018)“…Caffeine is a substance present in several foods and drinks of common western diet. Although high caffeine concentrations induce anxiogenic properties in…”
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Biochemical and Behavioral Responses in Zebrafish Exposed to Imidacloprid Oxidative Damage and Antioxidant Responses
Published in Archives of environmental contamination and toxicology (01-08-2021)“…Imidacloprid (IMI) is an insecticide used worldwide, a neonicotinoid that could cause toxicity in non-target organisms. Zebrafish ( Danio rerio ) is a model…”
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Phasic and tonic serotonin modulate alarm reactions and post‐exposure behavior in zebrafish
Published in Journal of neurochemistry (01-05-2020)“…Current theories on the role of serotonin (5‐HT) in vertebrate defensive behavior suggest that this monoamine increases anxiety but decreases fear, by acting…”
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Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae
Published in Toxicology and applied pharmacology (01-11-2013)“…The use of zebrafish (Danio rerio) is increasing as an intermediate preclinical model, to prioritize drug candidates for mammalian testing. As the immune…”
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Effects of ethanol and acetaldehyde in zebrafish brain structures: An in vitro approach on glutamate uptake and on toxicity-related parameters
Published in Toxicology in vitro (01-08-2014)“…•EtOH and ALD alter glutamate uptake in zebrafish brain structures.•The actions of EtOH and its metabolite are concentration and structure-dependent.•ALD…”
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Diet with diphenyl diselenide mitigates quinclorac toxicity in silver catfish (Rhamdia quelen)
Published in PloS one (03-12-2014)“…In this study, the protective effects of diphenyl diselenide [(PhSe)2] on quinclorac- induced toxicity were investigated in silver catfish (Rhamdia quelen)…”
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Lycorine induces cell death in the amitochondriate parasite, Trichomonas vaginalis, via an alternative non-apoptotic death pathway
Published in Phytochemistry (Oxford) (01-05-2011)“…Lycorine is cytotoxic against the amitochondriate parasite Trichomonas vaginalis by a mechanism of action that fails to fulfill the apoptotic-like cell death…”
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NTPDase family in zebrafish: Nucleotide hydrolysis, molecular identification and gene expression profiles in brain, liver and heart
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-03-2010)“…The nucleoside triphosphate diphosphohydrolase (NTPDase) family cleaves tri- and diphosphonucleosides to monophosphonucleosides and is responsible for…”
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Ethanol alters acetylcholinesterase activity and gene expression in zebrafish brain
Published in Toxicology letters (01-11-2007)“…Alcohol abuse is a health problem throughout the world and alcohol consumption is linked to the occurrence of several pathological conditions. Acute ethanol…”
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BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer
Published in Oncology (01-01-2010)“…Neurotrophin and neuropeptide pathways are emerging targets in cancer. Here we show that brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are…”
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Chronic ethanol treatment alters purine nucleotide hydrolysis and nucleotidase gene expression pattern in zebrafish brain
Published in Neurotoxicology (Park Forest South) (01-12-2011)“…► Decrease in ADP, GDP, AMP, and GMP hydrolysis was verified after ethanol treatment. ► NTPDase2_mv and NTPDase3 mRNA transcript levels decreased after ethanol…”
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Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish ( Danio rerio) brain
Published in Neurotoxicology (Park Forest South) (01-06-2010)“…Mercury is a widespread environmental contaminant that is neurotoxic even at very low concentrations. In this study we investigated the effects of mercury…”
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Analysis of the NTPDase and ecto-5'-nucleotidase profiles in serum-limited Trichomonas vaginalis
Published in Memórias do Instituto Oswaldo Cruz (01-03-2012)“…Trichomonas vaginalis is a parasite of the human urogenital tract that causes trichomonosis, the most prevalent non-viral sexually transmitted disease…”
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Evidence that acute taurine treatment alters extracellular AMP hydrolysis and adenosine deaminase activity in zebrafish brain membranes
Published in Neuroscience letters (06-09-2010)“…Taurine is one of the most abundant free amino acids in excitable tissues. In the brain, extracellular taurine may act as an inhibitory neurotransmitter,…”
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Kinetic characterization and gene expression of adenosine deaminase in intact trophozoites of Trichomonas vaginalis
Published in FEMS microbiology letters (01-06-2011)“…Abstract Trichomonas vaginalis is a parasite that resides in the human urogenital tract and causes trichomonosis, the most prevalent nonviral sexually…”
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Methanol alters ecto-nucleotidases and acetylcholinesterase in zebrafish brain
Published in Neurotoxicology and teratology (01-07-2006)“…Methanol is a neurotoxic compound that is responsible for serious damage on CNS. Besides being found as an environmental contaminant, this alcohol is also…”
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Ethanol and acetaldehyde alter NTPDase and 5′-nucleotidase from zebrafish brain membranes
Published in Neurochemistry international (01-01-2008)“…Alcohol abuse is an acute health problem throughout the world and alcohol consumption is linked to the occurrence of several pathological conditions. Here we…”
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Carbofuran and malathion inhibit nucleotide hydrolysis in zebrafish ( Danio rerio) brain membranes
Published in Toxicology (Amsterdam) (01-09-2005)“…Carbofuran and malathion are broad spectrum pesticides widely used in agricultural practice throughout the world. Toxicity of these pesticides has been…”
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