Search Results - "Roseborough, A. D."

Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model by Roseborough, A D, Myers, S J, Khazaee, R, Zhu, Y, Zhao, L, Iorio, E, Elahi, F M, Pasternak, S H, Whitehead, S N

“…Chronic microglia activation post-stroke is associated with worse neurological and cognitive outcomes. However, measurement of microglia activation in vivo is…”
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Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction by Roseborough, A.D., Zhu, Y., Zhao, L., Laviolette, S.R., Pasternak, S.H., Whitehead, S.N.

“…The brain's response to acute injury is characterized by increased permeability of the blood-brain barrier (BBB) and pro-inflammatory microglia signaling, both…”
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Editorial Focus: White matter-associated microglia (WAMs) represent an important link between aging, white matter disease and microglial activity by Roseborough, A. D., Jaremek, V. M., Whitehead, S. N.

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