Search Results - "Rose, Matthew"

An Extensive Case of Aplasia Cutis Congenita by Rose, Matthew D

“…Aplasia cutis congenita (ACC) is a rare connective tissue disorder that affects the epidermis, dermis, and subcutaneous tissue. Lesions can be small and…”
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Fcγ receptors: genetic variation, function, and disease by Hargreaves, Chantal E., Rose-Zerilli, Matthew J. J., Machado, Lee R., Iriyama, Chisako, Hollox, Edward J., Cragg, Mark S., Strefford, Jonathan C.

“…Summary Fcγ receptors (FcγRs) are key immune receptors responsible for the effective control of both humoral and innate immunity and are central to maintaining…”
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The spatiotemporal dynamics of microglia across the human lifespan by Menassa, David A, Muntslag, Tim A O, Martin-Estebané, Maria, Barry-Carroll, Liam, Chapman, Mark A, Adorjan, Istvan, Tyler, Teadora, Turnbull, Bethany, Rose-Zerilli, Matthew J J, Nicoll, James A R, Krsnik, Zeljka, Kostovic, Ivica, Gomez-Nicola, Diego

“…Microglia, the brain's resident macrophages, shape neural development and are key neuroimmune hubs in the pathological signatures of neurodevelopmental…”
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Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer by Hanley, Christopher J., Waise, Sara, Ellis, Matthew J., Lopez, Maria A., Pun, Wai Y., Taylor, Julian, Parker, Rachel, Kimbley, Lucy M., Chee, Serena J., Shaw, Emily C., West, Jonathan, Alzetani, Aiman, Woo, Edwin, Ottensmeier, Christian H., Rose-Zerilli, Matthew J. J., Thomas, Gareth J.

“…Fibroblasts are poorly characterised cells that variably impact tumour progression. Here, we use single cell RNA-sequencing, multiplexed immunohistochemistry…”
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The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea by Driver, Elizabeth Carroll, Sillers, Laura, Coate, Thomas M., Rose, Matthew F., Kelley, Matthew W.

“…The organ of Corti, located within the mammalian cochlea, contains a precise mosaic of hair cells (HC) and supporting cells (SC), the patterning of which is…”
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Single-cell analysis based dissection of clonality in myelofibrosis by Mylonas, Elena, Yoshida, Kenichi, Frick, Mareike, Hoyer, Kaja, Christen, Friederike, Kaeda, Jaspal, Obenaus, Matthias, Noerenberg, Daniel, Hennch, Cornelius, Chan, Willy, Ochi, Yotaro, Shiraishi, Yuichi, Shiozawa, Yusuke, Zenz, Thorsten, Oakes, Christopher C., Sawitzki, Birgit, Schwarz, Michaela, Bullinger, Lars, le Coutre, Philipp, Rose-Zerilli, Matthew J. J., Ogawa, Seishi, Damm, Frederik

“…Cancer development is an evolutionary genomic process with parallels to Darwinian selection. It requires acquisition of multiple somatic mutations that…”
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Math1 Expression Redefines the Rhombic Lip Derivatives and Reveals Novel Lineages within the Brainstem and Cerebellum by Wang, Vincent Y., Rose, Matthew F., Zoghbi, Huda Y.

“…The rhombic lip (RL) is an embryonic proliferative neuroepithelium that generates several groups of hindbrain neurons. However, the precise boundaries and…”
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An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing by Waise, Sara, Parker, Rachel, Rose-Zerilli, Matthew J. J., Layfield, David M., Wood, Oliver, West, Jonathan, Ottensmeier, Christian H., Thomas, Gareth J., Hanley, Christopher J.

“…Single-cell RNA sequencing (scRNA-Seq) provides a valuable platform for characterising multicellular ecosystems. Fibroblasts are a heterogeneous cell type…”
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P35 Quality improvement project – sleep studies on non-invasively ventilated patients in a general paediatric ward by Akbar, Sairah, Rose, Matthew

“…IntroductionThe ideal model is for children on Long Term Ventilation (LTV) is to be cared for in a non-critical care environment wherever possible (Paediatric…”
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The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial by Oscier, David G., Rose-Zerilli, Matthew J.J., Winkelmann, Nils, Gonzalez de Castro, David, Gomez, Belen, Forster, Jade, Parker, Helen, Parker, Anton, Gardiner, Anne, Collins, Andrew, Else, Monica, Cross, Nicholas C.P., Catovsky, Daniel, Strefford, Jonathan C.

“…NOTCH1 and SF3B1 mutations have been previously reported to have prognostic significance in chronic lymphocytic leukemia but to date they have not been…”
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Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial by Blakemore, Stuart J., Clifford, Ruth, Parker, Helen, Antoniou, Pavlos, Stec-Dziedzic, Ewa, Larrayoz, Marta, Davis, Zadie, Kadalyayil, Latha, Colins, Andrew, Robbe, Pauline, Vavoulis, Dimitris, Forster, Jade, Carr, Louise, Morilla, Ricardo, Else, Monica, Bryant, Dean, McCarthy, Helen, Walewska, Renata J., Steele, Andrew J., Chan, Jacqueline, Speight, Graham, Stankovic, Tanja, Cragg, Mark S., Catovsky, Daniel, Oscier, David G., Rose-Zerilli, Matthew J. J., Schuh, Anna, Strefford, Jonathan C.

“…Despite advances in chronic lymphocytic leukaemia (CLL) treatment, globally chemotherapy remains a central treatment modality, with chemotherapy trials…”
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Epidemiologic Patterns of Maxillofacial Trauma in a Metropolitan Area: A Retrospective Analysis by Rose, Matthew J., Cimba, Michael J., Day, Saxon, Bhatt, Poolak, Panchal, Neeraj, Ford, Brian P.

“…To illuminate epidemiologic trends of maxillofacial trauma in an urban setting over an 11-year period. We performed an exhaustive database search at the…”
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Molecular landscape of proliferative verrucous leukoplakia: a systematic review by Nissanka-Jayasuriya, Eranga H., Fenton, Tim R., Rose-Zerilli, Matthew J.J.

“…Proliferative verrucous leukoplakia (PVL) is a rare oral potentially malignant disorder characterised by multifocal origin and unpredictable long-term…”
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p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators by Birts, Charles N, Banerjee, Arindam, Darley, Matthew, Dunlop, Charles R, Nelson, Sarah, Nijjar, Sharandip K, Parker, Rachel, West, Jonathan, Tavassoli, Ali, Rose-Zerilli, Matthew J J, Blaydes, Jeremy P

“…High rates of glycolysis in cancer cells are a well-established characteristic of many human tumors, providing rapidly proliferating cancer cells with…”
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A latent-based segmentation framework for the investigation of charging behaviour of electric vehicle users by Pellegrini, Andrea, Diana, Marco, Matthew Rose, John

“…•Charging frequencies and patterns are estimated to be radically different between irregular and regular chargers.•Regular chargers are found to charge their…”
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Dual dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing by Harrington, Jack, Esteban, Luis Blay, Butement, Jonathan, Vallejo, Andres F, Lane, Simon I R, Sheth, Bhavwanti, Jongen, Maaike S A, Parker, Rachel, Stumpf, Patrick S, Smith, Rosanna C G, MacArthur, Ben D, Rose-Zerilli, Matthew J J, Polak, Marta E, Underwood, Tim, West, Jonathan

“…The future of single cell diversity screens involves ever-larger sample sizes, dictating the need for higher throughput methods with low analytical noise to…”
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Excitatory Neurons of the Proprioceptive, Interoceptive, and Arousal Hindbrain Networks Share a Developmental Requirement for Math1 by Rose, Matthew F., Ahmad, Kaashif A., Thaller, Christina, Zoghbi, Huda Y.

“…Hindbrain networks important for sensation and arousal contain diverse neuronal populations with distinct projections, yet share specific characteristics such…”
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Math1 Is Essential for the Development of Hindbrain Neurons Critical for Perinatal Breathing by Rose, Matthew F., Ren, Jun, Ahmad, Kaashif A., Chao, Hsiao-Tuan, Klisch, Tiemo J., Flora, Adriano, Greer, John J., Zoghbi, Huda Y.

“…Mice lacking the proneural transcription factor Math1 ( Atoh1) lack multiple neurons of the proprioceptive and arousal systems and die shortly after birth from…”
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Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization by Banerjee, Arindam, Birts, Charles N, Darley, Matthew, Parker, Rachel, Mirnezami, Alex H, West, Jonathan, Cutress, Ramsey I, Beers, Stephen A, Rose-Zerilli, Matthew J J, Blaydes, Jeremy P

“…Altered flux through major metabolic pathways is a hallmark of cancer cells and provides opportunities for therapy. Stem cell-like cancer (SCLC) cells can…”
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Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing by Parry, Marina, Rose-Zerilli, Matthew Jj, Ljungström, Viktor, Gibson, Jane, Wang, Jun, Walewska, Renata, Parker, Helen, Parker, Anton, Davis, Zadie, Gardiner, Anne, McIver-Brown, Neil, Kalpadakis, Christina, Xochelli, Aliki, Anagnostopoulos, Achilles, Fazi, Claudia, de Castro, David Gonzalez, Dearden, Claire, Pratt, Guy, Rosenquist, Richard, Ashton-Key, Margaret, Forconi, Francesco, Collins, Andrew, Ghia, Paolo, Matutes, Estella, Pangalis, Gerassimos, Stamatopoulos, Kostas, Oscier, David, Strefford, Jonathan C

“…Mounting evidence supports the clinical significance of gene mutations and immunogenetic features in common mature B-cell malignancies. We undertook a detailed…”
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