Search Results - "Rose, John W."
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Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta
Published in Lancet neurology (01-04-2010)“…Summary Background Daclizumab, a humanised monoclonal antibody, reduced multiple sclerosis disease activity in previous non-randomised studies. We aimed to…”
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Resveratrol Exacerbates Both Autoimmune and Viral Models of Multiple Sclerosis
Published in The American journal of pathology (01-11-2013)“…The polyphenol compound resveratrol is reported to have multiple functions, including neuroprotection, and no major adverse effects have been reported…”
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Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis
Published in Circulation research (27-04-2012)“…RATIONALE:Multiple sclerosis (MS) and its mouse model, experimental autoimmune encephalomyelitis (EAE), are inflammatory disorders of the central nervous…”
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Assessment of disability and disease burden in neuromyelitis optica spectrum disorders in the CIRCLES Cohort
Published in Scientific reports (30-10-2024)“…Neuromyelitis optica spectrum disorders (NMOSD) comprise autoimmune diseases imposing substantial disability. We compared an NMOSD-targeted disability…”
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Neurologic involvement in seronegative primary Sjögren's syndrome with positive minor salivary gland biopsy: a single-center experience
Published in Frontiers in neurology (09-06-2023)“…To assess the demographics, neurologic manifestations, comorbidities, and treatment of patients with seronegative primary Sjögren's syndrome (pSS). We…”
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Heat-transfer coefficients, Wilson plots and accuracy of thermal measurements
Published in Experimental thermal and fluid science (2004)“…The paper revisits well-known and well-understood topics concerning calculation methods and accuracy of heat-transfer measurements. Included are comments on…”
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Biopsy-proven PML in an HIV-negative patient with discoid lupus: Failure to detect JC virus in CSF
Published in Clinical neurology and neurosurgery (01-10-2021)“…We present a case of a 58-year-old man with a history of severe discoid lupus erythematosus and acute encephalopathy and incoordination. Antinuclear antibody…”
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High-b diffusivity of MS lesions in cervical spinal cord using ultrahigh-b DWI (UHb-DWI)
Published in NeuroImage clinical (01-01-2021)“…[Display omitted] •Ultrahigh-b DWI (UHb-DWI) method applied to MS spinal cords.•UHb-DWI provides quantitative measures of the MS lesions in the spinal…”
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Using diffusion tensor imaging and immunofluorescent assay to evaluate the pathology of multiple sclerosis
Published in Journal of magnetic resonance imaging (01-03-2011)“…Purpose: To determine the ability of the principal diffusion tensor imaging (DTI) indices to predict the underlying histopathology evaluated with…”
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Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics
Published in Journal of neuroinflammation (29-10-2009)“…Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders. Because…”
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Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death
Published in Journal of neuroinflammation (13-04-2010)“…We previously found that cyclooxygenase 2 (COX-2) was expressed in dying oligodendrocytes at the onset of demyelination in the Theiler's murine…”
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Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay
Published in Multiple sclerosis international (2021)“…Objective. Aquaporin-4 (AQP4) serum autoantibodies are detected by a variety of methods. The highest sensitivity is achieved with cell-based assays, but the…”
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Dropwise Condensation on Micro- and Nanostructured Surfaces
Published in Nanoscale and microscale thermophysical engineering (03-07-2014)“…In this review we cover recent developments in the area of surface-enhanced dropwise condensation against the background of earlier work. The development of…”
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Daclizumab: Development, Clinical Trials, and Practical Aspects of Use in Multiple Sclerosis
Published in Neurotherapeutics (01-10-2017)“…Daclizumab is a humanized monoclonal antibody directed towards CD25, the alpha subunit of the high-affinity interleukin (IL)-2 receptor. Daclizumab exerts its…”
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Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor
Published in Journal of neuroinflammation (17-02-2009)“…The EP1 receptor for the prostanoid PGE2 is a G-protein coupled receptor that has been shown to contribute to excitotoxic neuronal death. In this study we…”
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Characteristics of Children and Adolescents With Multiple Sclerosis
Published in Pediatrics (Evanston) (01-07-2016)“…To describe the demographic and clinical characteristics of pediatric multiple sclerosis (MS) in the United States. This prospective observational study…”
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Theory of heat transfer during condensation in microchannels
Published in International journal of heat and mass transfer (01-05-2011)“…A theoretical model for condensation in microchannels takes account of the effects of gravity and streamwise shear stress on the condensate surface as well as…”
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Hematopoietic stem cell transplantation for neuromyelitis optica spectrum disorder. Can immune tolerance be reestablished?
Published in Handbook of clinical neurology (2024)“…Neuromyelitis optica (NMO), which is also referred to as Devic's disease, was originally considered an aggressive subtype of multiple sclerosis (MS) presenting…”
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Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report
Published in Neurology (19-01-2016)“…OBJECTIVE:To compare clinical features of pediatric neuromyelitis optica (NMO) to other pediatric demyelinating diseases. METHODS:Review of a prospective…”
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An Integrated Experimental and Modeling Approach for Assessing High-Temperature Decomposition Kinetics of Explosives
Published in Journal of the American Chemical Society (25-09-2024)“…We present a new integrated experimental and modeling effort that assesses the intrinsic sensitivity of energetic materials based on their reaction rates. The…”
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