Search Results - "Rose, F.R.A.J"

Hydrogels derived from demineralized and decellularized bone extracellular matrix by Sawkins, M.J., Bowen, W., Dhadda, P., Markides, H., Sidney, L.E., Taylor, A.J., Rose, F.R.A.J., Badylak, S.F., Shakesheff, K.M., White, L.J.

“…The extracellular matrix (ECM) of mammalian tissues has been isolated, decellularized and utilized as a scaffold to facilitate the repair and reconstruction of…”
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Interconnectivity and permeability of supercritical fluid-foamed scaffolds and the effect of their structural properties on cell distribution by Reinwald, Y, Johal, R K, Ghaemmaghami, A M, Rose, F RAJ, Howdle, S M, Shakesheff, K M

“…This study aims to investigate interconnectivity and permeability of scCO sub(2)-foamed scaffolds and the influence of structural scaffold properties on cell…”
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Evaluation of skeletal tissue repair, Part 2: Enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model by Smith, E.L., Kanczler, J.M., Gothard, D., Roberts, C.A., Wells, J.A., White, L.J., Qutachi, O., Sawkins, M.J., Peto, H., Rashidi, H., Rojo, L., Stevens, M.M., El Haj, A.J., Rose, F.R.A.J., Shakesheff, K.M., Oreffo, R.O.C.

“…[Display omitted] There is an unmet need for improved, effective tissue engineering strategies to replace or repair bone damaged through disease or injury…”
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The influence of dispersant concentration on the pore morphology of hydroxyapatite ceramics for bone tissue engineering by Cyster, L.A., Grant, D.M., Howdle, S.M., Rose, F.R.A.J., Irvine, D.J., Freeman, D., Scotchford, C.A., Shakesheff, K.M.

“…There is a clinical need for synthetic scaffolds that will promote bone regeneration. Important factors include obtaining an optimal porosity and size of…”
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Porous Polymer and Cell Composites That Self-Assemble In Situ by Salem, A.K., Rose, F.R.A.J., Oreffo, R.O.C., Yang, X., Davies, M.C., Mitchell, J.R., Roberts, C.J., Stolnik-Trenkic, S., Tendler, S.J.B., Williams, P.M., Shakesheff, K.M.

“…A cell‐laden 3D network is formed upon the addition of avidin to biotinylated polymer particles in the presence of a suspension of cells (see Figure)…”
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In situ monitoring of 3D in vitro cell aggregation using an optical imaging system by Sawyer, N.B.E, Worrall, L.K, Crowe, J.A, Waters, S.L, Shakesheff, K.M, Rose, F.R.A.J, Morgan, S.P

“…Bioreactor systems that maintain cells and tissues in suspension are increasingly popular for culturing 3D constructs to avoid the loss of in vivo cell…”
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Post-processing of polymer foam tissue scaffolds with high power ultrasound: A route to increased pore interconnectivity, pore size and fluid transport by Watson, N.J., Johal, R.K., Glover, Z., Reinwald, Y., White, L.J., Ghaemmaghami, A.M., Morgan, S.P., Rose, F.R.A.J., Povey, M.J.W., Parker, N.G.

“…The aim of this work is to demonstrate that the structural and fluidic properties of polymer foam tissue scaffolds, post-fabrication but prior to the…”
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A design of experiments approach to identify the influencing parameters that determine poly-D,L-lactic acid (PDLLA) electrospun scaffold morphologies by Ruiter, F A A, Alexander, C, Rose, F R A J, Segal, J I

“…Electrospun fibrous materials have increasing applications in regenerative medicine due to the similarity of fibre constructs to the morphology of certain…”
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Evaluation of skeletal tissue repair, Part 1: Assessment of novel growth-factor-releasing hydrogels in an ex vivo chick femur defect model by Smith, E.L., Kanczler, J.M., Gothard, D., Roberts, C.A., Wells, J.A., White, L.J., Qutachi, O., Sawkins, M.J., Peto, H., Rashidi, H., Rojo, L., Stevens, M.M., El Haj, A.J., Rose, F.R.A.J., Shakesheff, K.M., Oreffo, R.O.C.

“…[Display omitted] Current clinical treatments for skeletal conditions resulting in large-scale bone loss include autograft or allograft, both of which have…”
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The effect of anisotropic architecture on cell and tissue infiltration into tissue engineering scaffolds by Silva, M.M.C.G., Cyster, L.A., Barry, J.J.A., Yang, X.B., Oreffo, R.O.C., Grant, D.M., Scotchford, C.A., Howdle, S.M., Shakesheff, K.M., Rose, F.R.A.J.

“…A common phenomenon in tissue engineering is rapid tissue formation on the outer edge of the scaffold which restricts cell penetration and nutrient exchange to…”
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A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells by Morris, G E, Bridge, J C, Brace, L A, Knox, A J, Aylott, J W, Brightling, C E, Ghaemmaghami, A M, Rose, F R A J

“…Conventional airway in vitro models focus upon the function of individual structural cells cultured in a two-dimensional monolayer, with limited…”
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Cell adhesion and mechanical properties of a flexible scaffold for cardiac tissue engineering by Hidalgo-Bastida, L.A., Barry, J.J.A., Everitt, N.M., Rose, F.R.A.J., Buttery, L.D., Hall, I.P., Claycomb, W.C., Shakesheff, K.M.

“…Cardiac tissue engineering is focused on obtaining functional cardiomyocyte constructs to provide an alternative to cellular cardiomyoplasty. Mechanical…”
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Tracking large solid constructs suspended in a rotating bioreactor: A combined experimental and theoretical study by Cummings, L.J., Sawyer, N.B.E., Morgan, S.P., Rose, F.R.A.J., Waters, S.L.

“…We present a combined experimental and theoretical study of the trajectory of a large solid cylindrical disc suspended within a fluid‐filled rotating…”
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Expression of antimicrobial neutrophil defensins in epithelial cells of active inflammatory bowel disease mucosa by Cunliffe, R N, Kamal, M, Rose, F R A J, James, P D, Mahida, Y R

“…Background/Aims: The normal intestinal epithelium is increasingly being recognised as an important component of the mucosal innate protection against…”
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