Search Results - "Rose, Carlos"

Ethical Conduct of Research in Children: Pediatricians and Their IRB (Part 1 of 2) by Rose, Carlos D

“…As human experimentation continues to grow into an ever more complex and sophisticated endeavor, the relevant ethical and regulatory structures become more…”
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Ethical Conduct of Research in Children: Pediatricians and Their IRB (Part 2 of 2) by Rose, Carlos D

“…In part 1 of this series, we discussed the historical, ethical, and legal background that provides justification for the current system of protection of…”
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Antibiotic Exposure and Juvenile Idiopathic Arthritis: A Case-Control Study by Horton, Daniel B, Scott, Frank I, Haynes, Kevin, Putt, Mary E, Rose, Carlos D, Lewis, James D, Strom, Brian L

“…Recent evidence has linked childhood antibiotic use and microbiome disturbance to autoimmune conditions. This study tested the hypothesis that antibiotic…”
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Blau Syndrome: A Systemic Granulomatous Disease of Cutaneous Onset and Phenotypic Complexity by Rose, Carlos D.

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Multinucleated Giant Cells: Current Insights in Phenotype, Biological Activities, and Mechanism of Formation by Ahmadzadeh, Kourosh, Vanoppen, Margot, Rose, Carlos D, Matthys, Patrick, Wouters, Carine Helena

“…Monocytes and macrophages are innate immune cells with diverse functions ranging from phagocytosis of microorganisms to forming a bridge with the adaptive…”
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Genome‐Wide Association Meta‐Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci by McIntosh, Laura A., Marion, Miranda C., Sudman, Marc, Comeau, Mary E., Becker, Mara L., Bohnsack, John F., Fingerlin, Tasha E., Griffin, Thomas A., Haas, J. Peter, Lovell, Daniel J., Maier, Lisa A., Nigrovic, Peter A., Prahalad, Sampath, Punaro, Marilynn, Rosé, Carlos D., Wallace, Carol A., Wise, Carol A., Moncrieffe, Halima, Howard, Timothy D., Langefeld, Carl D., Thompson, Susan D.

“…Objective Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic…”
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Modulation of the Excited States of Ruthenium(II)-perylene Dyad to Access Near-IR Luminescence, Long-Lived Perylene Triplet State and Singlet Oxygen Photosensitization by Campos, Isabele S., Fermi, Andrea, Ventura, Barbara, Moraes, Carlos A. F., Ribeiro, Gabriel H., Venâncio, Tiago, Ceroni, Paola, Carlos, Rose M.

“…Herein, we present a novel ruthenium­(II)-perylene dyad (RuPDI-Py) that combines the photophysical properties of pyrrolidine-substituted perylene diimide…”
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Blau Syndrome–Associated Uveitis: Preliminary Results From an International Prospective Interventional Case Series by Sarens, Inge L., Casteels, Ingele, Anton, Jordi, Bader-Meunier, Brigitte, Brissaud, Philippe, Chédeville, Gaelle, Cimaz, Rolando, Dick, Andrew D., Espada, Graciella, Fernandez-Martin, Jorge, Guly, Catherine M., Hachulla, Eric, Harjacek, Miroslav, Khubchandani, Raju, Mackensen, Friederike, Merino, Rosa, Modesto, Consuelo, Naranjo, Antonio, Oliveira-Knupp, Sheila, Özen, Seza, Pajot, Christine, Ramanan, Athimalaipet V., Russo, Ricardo, Susic, Gordana, Thatayatikom, Akaluck, Thomée, Caroline, Vastert, Sebastiaan, Bertin, John, Arostegui, Juan I., Rose, Carlos D., Wouters, Carine H.

“…Provide baseline and preliminary follow-up results in a 5-year longitudinal study of Blau syndrome. Multicenter, prospective interventional case series…”
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Blau syndrome, the prototypic auto-inflammatory granulomatous disease by Wouters, Carine H, Maes, Anne, Foley, Kevin P, Bertin, John, Rose, Carlos D

“…Blau syndrome is a monogenic disease resulting from mutations in the pattern recognition receptor NOD2, and is phenotypically characterized by the triad of…”
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Blau syndrome revisited by Rose, Carlos D, Martin, Tammy M, Wouters, Carine H

“…PURPOSE OF REVIEWBlau syndrome is a monogenic disease resulting from mutations in nucleotide oligomerization domain 2 (NOD2) and is phenotypically…”
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Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13 by Thompson, Susan D., Marion, Miranda C., Sudman, Marc, Ryan, Mary, Tsoras, Monica, Howard, Timothy D., Barnes, Michael G., Ramos, Paula S., Thomson, Wendy, Hinks, Anne, Haas, Johannes-Peter, Prahalad, Sampath, Bohnsack, John F., Wise, Carol A., Punaro, Marilynn, Rosé, Carlos D., Pajewski, Nicholas M., Spigarelli, Michael, Keddache, Mehdi, Wagner, Michael, Langefeld, Carl D., Glass, David N.

“…Objective In a genome‐wide association study of Caucasian patients with juvenile idiopathic arthritis (JIA), we have previously described findings limited to…”
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Multinucleation resets human macrophages for specialized functions at the expense of their identity by Ahmadzadeh, Kourosh, Pereira, Marie, Vanoppen, Margot, Bernaerts, Eline, Ko, Jeong‐Hun, Mitera, Tania, Maksoudian, Christy, Manshian, Bella B, Soenen, Stefaan, Rose, Carlos D, Matthys, Patrick, Wouters, Carine, Behmoaras, Jacques

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Validation of new medication use algorithms as proxies for worsening disease activity in patients with juvenile idiopathic arthritis by Saito, Kyoko, Gabbeta, Avinash, Mulvihill, Evan, Al‐Jaberi, Lina, Beukelman, Timothy, Lewis, James D., Rose, Carlos D., Strom, Brian L., Horton, Daniel B.

“…Purpose To facilitate claims‐based research on populations with juvenile idiopathic arthritis (JIA), we sought to validate an algorithm of new medication use…”
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S100A12 and S100A8/9 proteins are biomarkers of articular disease activity in Blau syndrome by Wang, Lin, Rosé, Carlos D, Foley, Kevin P, Anton, Jordi, Bader-Meunier, Brigitte, Brissaud, Philippe, Chédeville, Gaelle, Cimaz, Rolando, Fernández-Martín, Jorge, Guly, Catherine, Hachulla, Eric, Harjacek, Miroslav, Mackensen, Friederike, Merino, Rosa, Modesto, Consuelo, Naranjo Hernández, Antonio, Pajot, Christine, Ramanan, Athimalaipet V, Thatayatikom, Akaluck, Thomée, Caroline, Vastert, Sebastiaan, Votta, Bart J, Bertin, John, Wouters, Carine H

“…Abstract Objective To identify biomarkers of articular and ocular disease activity in patients with Blau syndrome (BS) Methods Multiplex plasma protein arrays…”
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Multinucleation resets human macrophages for specialized functions at the expense of their identity by Ahmadzadeh, Kourosh, Pereira, Marie, Vanoppen, Margot, Bernaerts, Eline, Ko, Jeong‐Hun, Mitera, Tania, Maksoudian, Christy, Manshian, Bella B, Soenen, Stefaan, Rose, Carlos D, Williams, Graham R, Bassett, J H Duncan, Matthys, Patrick, Wouters, Carine, Behmoaras, Jacques

“…Macrophages undergo plasma membrane fusion and cell multinucleation to form multinucleated giant cells (MGCs) such as osteoclasts in bone, Langhans giant cells…”
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Comparison of Aβ (1–40, 1–28, 11–22, and 29–40) aggregation processes and inhibition of toxic species generated in early stages of aggregation by a water-soluble ruthenium complex by Cali, Mariana P., Pereira, Lorena M.B., Teodoro, Marcio D., Sellani, Tarciso A., Rodrigues, Elaine G., Carlos, Rose M.

“…Neurotoxicity of amyloid beta (Aβ) species generated in early stages of aggregation has been associated with development of Alzheimer's disease (AD)…”
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Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis by Hinks, Anne, Cobb, Joanna, Marion, Miranda C, Prahalad, Sampath, Sudman, Marc, Bowes, John, Martin, Paul, Comeau, Mary E, Sajuthi, Satria, Andrews, Robert, Brown, Milton, Chen, Wei-Min, Concannon, Patrick, Deloukas, Panos, Edkins, Sarah, Eyre, Stephen, Gaffney, Patrick M, Guthery, Stephen L, Guthridge, Joel M, Hunt, Sarah E, James, Judith A, Keddache, Mehdi, Moser, Kathy L, Nigrovic, Peter A, Onengut-Gumuscu, Suna, Onslow, Mitchell L, Rosé, Carlos D, Rich, Stephen S, Steel, Kathryn J A, Wakeland, Edward K, Wallace, Carol A, Wedderburn, Lucy R, Woo, Patricia, Bohnsack, John F, Haas, Johannes Peter, Glass, David N, Langefeld, Carl D, Thomson, Wendy, Thompson, Susan D

“…Anne Hinks and colleagues identify 14 new susceptibility loci for juvenile idiopathic arthritis through targeted analyses of genomic regions implicated in…”
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Intraarticular Glucocorticoid Injection as Second-line Treatment for Lyme Arthritis in Children by Horton, Daniel B, Taxter, Alysha J, Davidow, Amy L, Groh, Brandt P, Sherry, David D, Rose, Carlos D

“…To determine whether second-line intraarticular glucocorticoid (IAGC) injection improves outcomes in children with persistently active Lyme arthritis after…”
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An international registry on autoinflammatory diseases: the Eurofever experience by Toplak, Natasa, Frenkel, Joost, Ozen, Seza, Lachmann, Helen J, Woo, Patricia, Koné-Paut, Isabelle, De Benedetti, Fabrizio, Neven, Benedicte, Hofer, Michael, Dolezalova, Pavla, Kümmerle-Deschner, Jasmin, Touitou, Isabelle, Hentgen, Veronique, Simon, Anna, Girschick, Herman, Rose, Carlos, Wouters, Carine, Vesely, Richard, Arostegui, Juan, Stojanov, Silvia, Ozgodan, Huri, Martini, Alberto, Ruperto, Nicolino, Gattorno, Marco

“…To report on the demographic data from the first 18 months of enrollment to an international registry on autoinflammatory diseases in the context of the…”
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Probing the acetylcholinesterase inhibitory activity of a novel Ru(II) polypyridyl complex and the supramolecular interaction by (STD)-NMR by Almeida, Marlon P., Kock, Flávio V.C., de Jesus, Hugo C.R., Carlos, Rose M., Venâncio, Tiago

“…Currently, acetylcholinesterase (AChE) inhibitors are the only anti-Alzheimer drugs commercially available. Despite their wide use those drugs are all dose…”
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