Search Results - "Rose, Alan B"

Introns as Gene Regulators: A Brick on the Accelerator by Rose, Alan B

“…A picture is beginning to emerge from a variety of organisms that for a subset of genes, the most important sequences that regulate expression are situated not…”
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Comparative and functional analysis of intron-mediated enhancement signals reveals conserved features among plants by Parra, G., Bradnam, K., Rose, Alan B., Korf, Ian

“…Introns in a wide range of organisms including plants, animals and fungi are able to increase the expression of the gene that they are contained in. This…”
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effect of intron location on intron-mediated enhancement of gene expression in Arabidopsis by Rose, A.B

“…Summary Introns are often required for full expression of genes in organisms as diverse as plants, insects, nematodes, yeast, and mammals. To explore the…”
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The effects of a stimulating intron on the expression of heterologous genes in Arabidopsis thaliana by Emami, Shahram, Arumainayagam, Dinah, Korf, Ian, Rose, Alan B

“…Introns are often added to transgenes to increase expression, although the mechanism through which introns stimulate gene expression in plants and other…”
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Evidence for a DNA-Based Mechanism of Intron-Mediated Enhancement by Rose, Alan B, Emami, Shahram, Bradnam, Keith, Korf, Ian

“…Many introns significantly increase gene expression through a process termed intron-mediated enhancement (IME). Introns exist in the transcribed DNA and the…”
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The enduring mystery of intron-mediated enhancement by Gallegos, Jenna E., Rose, Alan B.

“…•A subset of introns substantially increase gene expression.•The mechanisms through which many introns boost mRNA accumulation remain unknown.•The properties…”
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Intron DNA Sequences Can Be More Important Than the Proximal Promoter in Determining the Site of Transcript Initiation by Gallegos, Jenna E., Rose, Alan B.

“…To more precisely define the positions from which certain intronic regulatory sequences increase mRNA accumulation, the effect of a UBIQUITIN intron on gene…”
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An intron-derived motif strongly increases gene expression from transcribed sequences through a splicing independent mechanism in Arabidopsis thaliana by Gallegos, Jenna E., Rose, Alan B.

“…Certain introns significantly increase mRNA accumulation by a poorly understood mechanism. These introns have no effect when located upstream, or more than ~1…”
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Intron sequences that stimulate gene expression in Arabidopsis by Rose, Alan B., Carter, Amanda, Korf, Ian, Kojima, Noah

“…Key message Related motifs strongly increase gene expression when added to an intron located in coding sequences. Many introns greatly increase gene expression…”
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Promoter-Proximal Introns in Arabidopsis thaliana Are Enriched in Dispersed Signals that Elevate Gene Expression by Rose, Alan B, Elfersi, Tali, Parra, Genis, Korf, Ian

“…Introns that elevate mRNA accumulation have been found in a wide range of eukaryotes. However, not all introns affect gene expression, and direct testing is…”
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Intron-Mediated Enhancement of Gene Expression Independent of Unique Intron Sequences and Splicing by Rose, Alan B., Jason A. Beliakoff

“…Either of the first two introns of the Arabidopsis tryptophan pathway gene PAT1 elevates mRNA accumulation from a PAT1:β-glucuronidase (GUS) fusion roughly…”
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Requirements for intron-mediated enhancement of gene expression in Arabidopsis by ROSE, ALAN B.

“…To explore possible mechanisms of intron-mediated enhancement of gene expression, the features of PAT1 intron 1 required to elevate mRNA accumulation were…”
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Post-fire recovery of a dryland forest remnant in the Wither Hills, Marlborough by Richardson, Sarah J., King, Susan, Rose, Alan B., McGlone, Matt S., Holdaway, Robert J.

“…Fire is a major threat to remnant native woody vegetation in dry, lowland New Zealand. This is because the woody flora lacks specific adaptations to survive…”
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Plant gene expression in the age of systems biology: integrating transcriptional and post-transcriptional events by Belostotsky, Dmitry A., Rose, Alan B.

“…The extensive mechanistic and regulatory interconnections between the various events of mRNA biogenesis are now recognized as a fundamental principle of…”
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A phosphoribosylanthranilate transferase gene is defective in blue fluorescent Arabidopsis thaliana tryptophan mutants by Rose, A.B, Casselman, A.L, Last, R.L

“…An Arabidopsis thaliana gene encoding phosphoribosylanthranilate transferase is shown to be the gene that is defective in blue fluorescent trp1 mutant plants…”
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Introns act post‐transcriptionally to increase expression of the Arabidopsis thaliana tryptophan pathway gene PAT1 by Rose, Alan B., Last, Robert L.

“…Summary The expression of the Arabidopsis thaliana PAT1 gene, which encodes the tryptophan biosynthetic enzyme phosphoribosylanthranilate transferase, was…”
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Applying word-based algorithms: the IMEter by Korf, Ian F, Rose, Alan B

“…Important patterns can be found in strings of characters such as nucleotides in a DNA sequence by examining the frequency of occurrence of specific character…”
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Recovery, invasion, and decline over 37 years in a Marlborough short-tussock grassland, New Zealand by Rose, Alan B., Suisted, Philip A., Frampton, Chris M.

“…The composition of humid, unfertilised, short-tussock (Festuca-Rytidosperma-Poa) grasslands was recorded on 42 permanent transects in 1959, 1970-72, and…”
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Hyperactivation of the silencing proteins, Sir2p and Sir3p, causes chromosome loss by Holmes, S.G, Rose, A.B, Steuerle, K, Saez, E, Sayegh, S, Lee, Y.M, Broach, J.R

“…The SIRgene products maintain transcriptional repression at the silent mating type loci and telomeres in Saccharomyces cerevisiae, although no enzymatic or…”
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An allelic series of blue fluorescent trp1 mutants of Arabidopsis thaliana by Rose, A.B. (University of California, Davis, CA.), Li, J.Y, Last, R.L

“…Nine blue fluorescent mutants of the flowering plant Arabidopsis thaliana were isolated by genetic selections and fluorescence screens. Each was shown to…”
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