Search Results - "Rosche, Fred"

Refine Results
  1. 1

    Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme by Gnoth, Kathrin, Bär, Joachim Wolfgang, Rosche, Fred, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich

    Published in PloS one (16-04-2024)
    “…Dipeptidyl peptidase 4 (DP4)/CD26 regulates the biological function of various peptide hormones by releasing dipeptides from their N-terminus. The enzyme is a…”
    Get full text
    Journal Article
  2. 2
  3. 3

    Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography–mass spectrometry by Wolf, Raik, Hoffmann, Torsten, Rosche, Fred, Demuth, Hans-Ulrich

    “…The incretins, glucose-dependent insulinotropic peptide (GIP 1–42) and glucagon-like peptide 1 (GLP-1 7–36), are involved in regulation of gastric emptying,…”
    Get full text
    Journal Article
  4. 4

    Metabolism of glucagon by dipeptidyl peptidase IV (CD26) by Pospisilik, John A, Hinke, Simon A, Pederson, Raymond A, Hoffmann, Torsten, Rosche, Fred, Schlenzig, Dagmar, Glund, Konrad, Heiser, Ulrich, McIntosh, Christopher H.S, Demuth, Hans-Ulrich

    Published in Regulatory peptides (12-01-2001)
    “…Glucagon is a 29-amino acid polypeptide released from pancreatic islet α-cells that acts to maintain euglycemia by stimulating hepatic glycogenolysis and…”
    Get full text
    Journal Article
  5. 5

    Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility by Kirchberg, Martin, Eick, Sigrun, Buchholz, Mirko, Rosche, Fred, Kiesow, Andreas, Sarembe, Sandra, Mäder, Karsten

    Published in International journal of pharmaceutics (30-08-2020)
    “…[Display omitted] We describe the development of flexible minocycline-lipid-complex extrudates with optimized mechanical and drug release properties. These…”
    Get full text
    Journal Article
  6. 6
  7. 7

    Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme by Kathrin Gnoth, Joachim Wolfgang Bär, Fred Rosche, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth

    Published in PloS one (01-01-2024)
    “…Dipeptidyl peptidase 4 (DP4)/CD26 regulates the biological function of various peptide hormones by releasing dipeptides from their N-terminus. The enzyme is a…”
    Get full text
    Journal Article
  8. 8
  9. 9

    Isolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization by Wagner, Leona, Wermann, Michael, Rosche, Fred, Rahfeld, Jens-Ulrich, Hoffmann, Torsten, Demuth, Hans-Ulrich

    Published in Biological chemistry (01-07-2011)
    “…Abstract In the present studies we resolved the post-translational microheterogeneity of purified porcine dipeptidyl peptidase IV (DP 4) from kidney cortex…”
    Get more information
    Journal Article
  10. 10

    Isoaspartate residues dramatically influence substrate recognition and turnover by proteases by Böhme, Livia, Bär, Joachim Wolfgang, Hoffmann, Torsten, Manhart, Susanne, Ludwig, Hans-Henning, Rosche, Fred, Demuth, Hans-Ulrich

    Published in Biological chemistry (01-08-2008)
    “…Posttranslational modifications influence the structure, stability and biological activity of proteins. Most of the reactions are enzyme-catalyzed, but some,…”
    Get more information
    Journal Article
  11. 11

    Heterologous Expression and Characterization of Human Glutaminyl Cyclase:  Evidence for a Disulfide Bond with Importance for Catalytic Activity by Schilling, Stephan, Hoffmann, Torsten, Rosche, Fred, Manhart, Susanne, Wasternack, Claus, Demuth, Hans-Ulrich

    Published in Biochemistry (Easton) (03-09-2002)
    “…Glutaminyl cyclase (QC, EC 2.3.2.5) catalyzes the formation of pyroglutamate residues from glutamine at the N-terminus of peptides and proteins. In the current…”
    Get full text
    Journal Article
  12. 12
  13. 13
  14. 14
  15. 15

    Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide by Pauly, Robert P., Demuth, Hans-Ulrich, Rosche, Fred, Schmidt, Jörn, White, Heather A., Lynn, Francis, McIntosh, Christopher H.S., Pederson, Raymond A.

    Published in Metabolism, clinical and experimental (01-03-1999)
    “…The incretins glucose-dependent insulinotropic polypeptide (GIP 1–42) and truncated forms of glucagon-like peptide-1 (GLP-1) are hormones released from the gut…”
    Get full text
    Journal Article
  16. 16
  17. 17

    Triorganotin Fluoride Structures: A Ligand Close-Packing Model with Predominantly Ionic Sn−F Bonds by Beckmann, Jens, Horn, Dagmar, Jurkschat, Klaus, Rosche, Fred, Schürmann, Markus, Zachwieja, Uwe, Dakternieks, Dainis, Duthie, Andrew, Lim, Allan E. K.

    Published in European journal of inorganic chemistry (01-01-2003)
    “…The synthesis and complete characterization by multinuclear NMR, infrared, and Mössbauer spectroscopy, by single crystal X‐ray analysis, as well as by…”
    Get full text
    Journal Article
  18. 18
  19. 19
  20. 20