Search Results - "Rosche, Fred"
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Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme
Published in PloS one (16-04-2024)“…Dipeptidyl peptidase 4 (DP4)/CD26 regulates the biological function of various peptide hormones by releasing dipeptides from their N-terminus. The enzyme is a…”
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Simple Purification of Nicotiana benthamiana-Produced Recombinant Colicins: High-Yield Recovery of Purified Proteins with Minimum Alkaloid Content Supports the Suitability of the Host for Manufacturing Food Additives
Published in International journal of molecular sciences (29-12-2017)“…Colicins are natural non-antibiotic bacterial proteins with a narrow spectrum but an extremely high antibacterial activity. These proteins are promising food…”
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Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography–mass spectrometry
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-04-2004)“…The incretins, glucose-dependent insulinotropic peptide (GIP 1–42) and glucagon-like peptide 1 (GLP-1 7–36), are involved in regulation of gastric emptying,…”
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Metabolism of glucagon by dipeptidyl peptidase IV (CD26)
Published in Regulatory peptides (12-01-2001)“…Glucagon is a 29-amino acid polypeptide released from pancreatic islet α-cells that acts to maintain euglycemia by stimulating hepatic glycogenolysis and…”
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Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility
Published in International journal of pharmaceutics (30-08-2020)“…[Display omitted] We describe the development of flexible minocycline-lipid-complex extrudates with optimized mechanical and drug release properties. These…”
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Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme
Published in PloS one (01-01-2024)“…Dipeptidyl peptidase 4 (DP4)/CD26 regulates the biological function of various peptide hormones by releasing dipeptides from their N-terminus. The enzyme is a…”
Get full text
Journal Article -
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Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Published in The Journal of biological chemistry (01-09-1996)Get full text
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Isolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization
Published in Biological chemistry (01-07-2011)“…Abstract In the present studies we resolved the post-translational microheterogeneity of purified porcine dipeptidyl peptidase IV (DP 4) from kidney cortex…”
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Isoaspartate residues dramatically influence substrate recognition and turnover by proteases
Published in Biological chemistry (01-08-2008)“…Posttranslational modifications influence the structure, stability and biological activity of proteins. Most of the reactions are enzyme-catalyzed, but some,…”
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Heterologous Expression and Characterization of Human Glutaminyl Cyclase: Evidence for a Disulfide Bond with Importance for Catalytic Activity
Published in Biochemistry (Easton) (03-09-2002)“…Glutaminyl cyclase (QC, EC 2.3.2.5) catalyzes the formation of pyroglutamate residues from glutamine at the N-terminus of peptides and proteins. In the current…”
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Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel kinetic approach
Published in The Journal of biological chemistry (20-09-1996)“…The incretins glucose-dependent insulinotropic polypeptide (GIP1-42) and glucagon-like peptide-1-(7-36)-amide (GLP-17-36), hormones that potentiate…”
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Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography-mass spectrometry: Peptide Separation & Analysis
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2004)Get full text
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Immunoprecipitation and liquid chromatographic-mass spectrometric determination of the peptide glucose-dependent insulinotropic polypeptides GIP1-42 and GIP3-42 from human plasma samples new sensitive method to analyze physiological concentrations of peptide hormones
Published in Journal of chromatography (10-08-2001)“…The gastrointestinal peptide glucose-dependent insulinotropic polypeptide (GIP1-42) is one of the incretin hormones regulating glucose-induced insulin…”
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Conference Proceeding Journal Article -
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Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide
Published in Metabolism, clinical and experimental (01-03-1999)“…The incretins glucose-dependent insulinotropic polypeptide (GIP 1–42) and truncated forms of glucagon-like peptide-1 (GLP-1) are hormones released from the gut…”
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Triorganotin Fluoride Structures: A Ligand Close-Packing Model with Predominantly Ionic Sn−F Bonds
Published in European journal of inorganic chemistry (01-01-2003)“…The synthesis and complete characterization by multinuclear NMR, infrared, and Mössbauer spectroscopy, by single crystal X‐ray analysis, as well as by…”
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Immunoprecipitation and liquid chromatographic–mass spectrometric determination of the peptide glucose-dependent insulinotropic polypeptides GIP 1-42 and GIP 3-42 from human plasma samples : New sensitive method to analyze physiological concentrations of peptide hormones
Published in Journal of Chromatography A (2001)“…The gastrointestinal peptide glucose-dependent insulinotropic polypeptide (GIP 1-42) is one of the incretin hormones regulating glucose-induced insulin…”
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Characterization of povidone products by means of ^sup 13^C-NMR, MALDI-TOF, and electrospray mass spectrometry
Published in Pharmaceutical research (01-04-2002)Get full text
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Characterization of povidone products by means of 13C-NMR, MALDI-TOF, and electrospray mass spectrometry
Published in Pharmaceutical research (01-04-2002)Get full text
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