Search Results - "Rosario, Virgilio do E"
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Novel Potent Metallocenes against Liver Stage Malaria
Published in Antimicrobial Agents and Chemotherapy (01-03-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Prevalence and genetic diversity of Babesia and Anaplasma species in cattle in Sudan
Published in Veterinary parasitology (27-09-2011)“…Disease prevalence studies are one of the most valuable tools to demonstrate the risk or impact of certain infections in local and global economies. The data…”
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3
Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea
Published in Malaria journal (27-03-2013)“…In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source…”
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Expression and characterization of the Babesia bigemina cysteine protease BbiCPL1
Published in Acta tropica (01-01-2012)“…BbiCPL1 showed characteristic properties of a cysteine protease. At pH 7.5, BbiCPL1 maintained 83% of maximum activity, suggesting a role in cytosol…”
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5
Chloroquine mediated modulation of Anopheles gambiae gene expression
Published in PloS one (02-07-2008)“…Plasmodium development in the mosquito is crucial for malaria transmission and depends on the parasite's interaction with a variety of cell types and specific…”
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Application of loop-mediated isothermal amplification for malaria diagnosis during a follow-up study in São Tomé
Published in Malaria journal (06-12-2012)“…A reliable and simple test for the detection of malaria parasite is crucial in providing effective treatment and therapeutic follow-up, especially in malaria…”
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7
Detection of bovine babesiosis in Mozambique by a novel seminested hot-start PCR method
Published in Veterinary parasitology (31-05-2008)“…Babesiosis is a tick borne disease (TBD) caused by parasites of the genus Babesia, with considerable worldwide economic, medical, and veterinary impact. Bovine…”
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Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola
Published in Malaria journal (02-02-2011)“…Malaria is the major cause of morbidity and mortality in Angola. The most vulnerable groups to Plasmodium falciparum infection are pregnant women and children…”
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Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs
Published in European journal of medicinal chemistry (01-06-2009)“…Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus were synthesized and evaluated as potential transmission-blocking…”
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10
Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola
Published in Malaria journal (17-11-2008)“…Malaria is the infectious disease causing the highest morbidity and mortality in Angola and due to widespread chloroquine (CQ) resistance, the country has…”
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11
Prevalence and risk factors of Plasmodium falciparum infections in pregnant women of Luanda, Angola
Published in Tropical medicine & international health (01-10-2011)“…Summary Pregnant women are at increased risk of malaria, but in Angola, epidemiologic data from this group is almost inexistent. We conducted a cross‐sectional…”
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Malaria: looking for selection signatures in the human PKLR gene region
Published in British journal of haematology (01-06-2010)“…Summary The genetic component of susceptibility to malaria is both complex and multigenic and the better‐known protective polymorphisms are those involving…”
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13
Molecular evolution of the three short PGRPs of the malaria vectors Anopheles gambiae and Anopheles arabiensis in East Africa
Published in BMC evolutionary biology (12-01-2010)“…Immune responses to parasites, which start with pathogen recognition, play a decisive role in the control of the infection in mosquitoes. Peptidoglycan…”
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Identification of papain-like cysteine proteases from the bovine piroplasm Babesia bigemina and evolutionary relationship of piroplasms C1 family of cysteine proteases
Published in Experimental parasitology (2011)“…Papain-like cysteine proteases have been shown to have essential roles in parasitic protozoa and are under study as promising drug targets. Five genes were…”
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Analysis of genetic mutations associated with anti-malarial drug resistance in Plasmodium falciparum from the Democratic Republic of East Timor
Published in Malaria journal (09-04-2009)“…In response to chloroquine (CQ) resistance, the policy for the first-line treatment of uncomplicated malaria in the Democratic Republic of East Timor (DRET)…”
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16
Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant
Published in Malaria journal (23-03-2007)“…Plasmodium falciparum is the predominant human malaria species in Mozambique and a lead cause of mortality among children and pregnant women nationwide…”
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Plasmodium vivax in the Democratic Republic of East Timor: Parasite prevalence and antifolate resistance-associated mutations
Published in Acta tropica (01-09-2010)“…Plasmodium vivax isolates from East Timor were inspected for particular mutations in the dhfr and dhps genes, associated with resistance to antifolate drugs…”
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A carbamate-based approach to primaquine prodrugs: Antimalarial activity, chemical stability and enzymatic activation
Published in Bioorganic & medicinal chemistry (15-01-2012)“…O-Alkyl carbamate derivatives of primaquine were shown to display potent transmission-blocking antimalarial activity. O-Alkyl and O-aryl carbamate derivatives…”
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Two Nonrecombining Sympatric Forms of the Human Malaria Parasite Plasmodium ovale Occur Globally
Published in The Journal of infectious diseases (15-05-2010)“…Background. Malaria in humans is caused by apicomplexan parasites belonging to 5 species of the genus Plasmodium. Infections with Plasmodium ovale are widely…”
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Epidemiological characterization of Plasmodium falciparum in the Republic of Cabo Verde: implications for potential large-scale re-emergence of malaria
Published in Malaria journal (21-04-2006)“…Malaria has come near eradication at archipelago of Cabo Verde in 1970. Infections are now only observed in Santiago, where outbreaks occur. In these islands,…”
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