Search Results - "Rosales, Rafael T.M."

A kit formulation for the preparation of [89Zr]Zr(oxinate)4 for PET cell tracking: White blood cell labelling and comparison with [111In]In(oxinate)3 by Man, Francis, Khan, Azalea A., Carrascal-Miniño, Amaia, Blower, Philip J., T.M. de Rosales, Rafael

“…Advances in immunology and cell-based therapies are creating a need to track individual cell types, such as immune cells (neutrophils, eosinophils, chimeric…”
Get full text

Lung inflammation does not affect the clearance kinetics of lipid nanocapsules following pulmonary administration by Patel, Aateka, Woods, A., Riffo-Vasquez, Yanira, Babin-Morgan, Anna, Jones, Marie-Christine, Jones, Stuart, Sunassee, Kavitha, Clark, Stephen, T. M. de Rosales, Rafael, Page, Clive, Spina, Domenico, Forbes, Ben, Dailey, Lea Ann

“…Lipid nanocapsules (LNCs) are semi-rigid spherical capsules with a triglyceride core that present a promising formulation option for the pulmonary delivery of…”
Get full text

Abstracts of the 28th International Isotope Society (UK group) Symposium: The synthesis and applications of labelled compounds 2019 by Nelson, Adam, Phipps, Robert J., Crane, Georgie J., Venanzi, Niccolo A.E., Lockley, William J.S., Tredwell, Matthew, Buurma, Niklaas J., Ballard, Andrew, Ahmad, Hiwa O., Narduolo, Stefania, Rosa, Lucy, Chand, Nikki, Cosgrove, David A., Varkonyi, Peter, Asaad, Nabil, Tomasi, Simone, Leach, Andrew G., Summerhill, Nick, Bloom, Jon, Newby, Mark, Madden, Stephen, Roman, Daniela, Exner, Ruediger M., Cortezon‐Tamarit, Fernando, Ge, Haobo, Paisey, Stephen, Pascu, Sofia I., Rosales, Rafael T.M., Hailes, Helen C., Wang, Yu, Zhao, Jianxiong, Méndez‐Sánchez, Daniel, Rodan, Rebecca, Subrizi, Fabiana, Lichman, Benjamin R., Keep, Nicholas H., Ward, John M., Harris, Mark, Lamb, Martin, Wilson, Vernon, Iafrate, Peter, Bulat, Flaviu, Néves, Andre A., Hesse, Friederike, Hu, De‐En, Aigbirhio, Franklin, Leeper, Finian J., Brindle, Kevin M., Rowbotham, Jack S., Urata, Koji, Reeve, Holly A., Vincent, Kylie A., Hueting, Rebekka

Get full text

The Use of Contrast Agents in Clinical and Preclinical PET-MR Imaging by Sandiford, Lydia, PhD, de Rosales, Rafael T.M., PhD

“…PET-MR imaging is an exciting field of research for imaging chemists that allows for innovative approaches such as the use of cocktails of agents or bimodal…”
Get full text

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging by Gawne, Peter J., Man, Francis, Blower, Philip J., T. M. de Rosales, Rafael

“…The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically…”
Get full text

Translational considerations in nanomedicine: The oncology perspective by Gabizon, Alberto A., de Rosales, Rafael T.M., La-Beck, Ninh M.

“…Nanoparticles can provide effective control of the release rate and tissue distribution of their drug payload, leading to major pharmacokinetic and…”
Get full text

Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models by Volpe, Alessia, Lang, Cameron, Lim, Lindsay, Man, Francis, Kurtys, Ewelina, Ashmore-Harris, Candice, Johnson, Preeth, Skourti, Elena, de Rosales, Rafael T.M., Fruhwirth, Gilbert O.

“…Chimeric antigen receptor T cell therapy (CAR-T) has been rolled out as a new treatment for hematological malignancies. For solid tumor treatment, CAR-T has…”
Get full text

O-31 - [89Zr]Zr(oxinate)4 radiolabelling of human neutrophil extracellular microvesicles (EVs): in vivo PET imaging reveals extensive uptake in lymph nodes and brain in a mouse model of rheumatoid arthritis by de Rosales, Rafael T.M., Khan, Azalea, Man, Francis, Minino, Amaia Carrascal, Kim, Jana, Pellico, Juan

Get full text

[89Zr]Zr(oxinate)4 radiolabelling of human neutrophil extracellular microvesicles (EVs): in vivo PET imaging reveals extensive uptake in lymph nodes and brain in a mouse model of rheumatoid arthritis by de Rosales, Rafael T.M., Khan, Azalea, Man, Francis, Minino, Amaia Carrascal, Kim, Jana, Pellico, Juan

Get full text

Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility by Poley, Maria, Mora-Raimundo, Patricia, Shammai, Yael, Kaduri, Maya, Koren, Lilach, Adir, Omer, Shklover, Jeny, Shainsky-Roitman, Janna, Ramishetti, Srinivas, Man, Francis, de Rosales, Rafael T. M, Zinger, Assaf, Peer, Dan, Ben-Aharon, Irit, Schroeder, Avi

“…Throughout the female menstrual cycle, physiological changes occur that affect the biodistribution of nanoparticles within the reproductive system. We…”
Get full text

Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging by Sandiford, Lydia, Phinikaridou, Alkystis, Protti, Andrea, Meszaros, Levente K, Cui, Xianjin, Yan, Yong, Frodsham, George, Williamson, Peter A, Gaddum, Nicholas, Botnar, René M, Blower, Philip J, Green, Mark A, de Rosales, Rafael T. M

“…The efficient delivery of nanomaterials to specific targets for in vivo biomedical imaging is hindered by rapid sequestration by the reticuloendothelial system…”
Get full text

Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation by Carter, Thomas J., Agliardi, Giulia, Lin, Fang‐Yu, Ellis, Matthew, Jones, Clare, Robson, Mathew, Richard‐Londt, Angela, Southern, Paul, Lythgoe, Mark, Zaw Thin, May, Ryzhov, Vyacheslav, Rosales, Rafael T. M., Gruettner, Cordula, Abdollah, Maha R. A., Pedley, R. Barbara, Pankhurst, Quentin A., Kalber, Tammy L., Brandner, Sebastian, Quezada, Sergio, Mulholland, Paul, Shevtsov, Maxim, Chester, Kerry

“…Magnetic hyperthermia (MH) harnesses the heat‐releasing properties of superparamagnetic iron oxide nanoparticles (SPIONs) and has potential to stimulate immune…”
Get full text

Manganese-52: applications in cell radiolabelling and liposomal nanomedicine PET imaging using oxine (8-hydroxyquinoline) as an ionophore by Gawne, Peter, Man, Francis, Fonslet, Jesper, Radia, Riya, Bordoloi, Jayanta, Cleveland, Matthew, Jimenez-Royo, Pilar, Gabizon, Alberto, Blower, Philip J, Long, Nicholas, de Rosales, Rafael T M

“…The ionophore 8-hydroxyquinoline (oxine) has been used to radiolabel cells and liposomal medicines with 111In and, more recently, 89Zr, for medical nuclear…”
Get more information

Aluminium hydroxide stabilised MnFe2O4 and Fe3O4 nanoparticles as dual-modality contrasts agent for MRI and PET imaging by Cui, Xianjin, Belo, Salome, Krüger, Dirk, Yan, Yong, de Rosales, Rafael T M, Jauregui-Osoro, Maite, Ye, Haitao, Su, Shi, Mathe, Domokos, Kovács, Noémi, Horváth, Ildikó, Semjeni, Mariann, Sunassee, Kavitha, Szigeti, Krisztian, Green, Mark A, Blower, Philip J

“…Magnetic nanoparticles (NPs) MnFe2O4 and Fe3O4 were stabilised by depositing an Al(OH)3 layer via a hydrolysis process. The particles displayed excellent…”
Get full text

PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling by Khan, Azalea A, Man, Francis, Faruqu, Farid N, Kim, Jana, Al-Salemee, Fahad, Carrascal-Miniño, Amaia, Volpe, Alessia, Liam-Or, Revadee, Simpson, Paul, Fruhwirth, Gilbert O, Al-Jamal, Khuloud T, T. M. de Rosales, Rafael

“…Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their potential as drug delivery systems and biomarkers of disease…”
Get full text

Radiolabelling of Extracellular Vesicles for PET and SPECT imaging by Khan, Azalea A, T M de Rosales, Rafael

“…Extracellular vesicles (EVs) such as exosomes and microvesicles have gained recent attention as potential biomarkers of disease as well as nanomedicinal tools,…”
Get full text

On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study by Lacerda, Sara, Zhang, Wuyuan, T. M. de Rosales, Rafael, Da Silva, Isidro, Sobilo, Julien, Lerondel, Stéphanie, Tóth, Éva, Djanashvili, Kristina

“…Porous materials, such as zeolites, have great potential for biomedical applications, thanks to their ability to accommodate positively charged metal-ions and…”
Get full text

Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain by Lim Kee Chang, William, Chan, Tiffany G., Raguseo, Federica, Mishra, Aishwarya, Chattenton, Dani, de Rosales, Rafael T. M., Long, Nicholas J., Morse, Sophie V.

“…Focused ultrasound and microbubbles can non-invasively and locally deliver therapeutics and imaging agents across the blood–brain barrier. Uniform treatment…”
Get full text

Magnetically Decorated Multiwalled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents by Wang, Julie Tzu-Wen, Cabana, Laura, Bourgognon, Maxime, Kafa, Houmam, Protti, Andrea, Venner, Kerrie, Shah, Ajay M., Sosabowski, Jane K., Mather, Stephen J., Roig, Anna, Ke, Xiaoxing, Van Tendeloo, Gustaaf, de Rosales, Rafael T. M., Tobias, Gerard, Al-Jamal, Khuloud T.

“…Carbon nanotubes (CNTs) are one of the most promising nanomaterials to be used in biomedicine for drug/gene delivery as well as biomedical imaging. This study…”
Get full text

Technetium-99m and rhenium-188 complexes with one and two pendant bisphosphonate groups for imaging arterial calcification by Bordoloi, Jayanta Kumar, Berry, David, Khan, Irfan Ullah, Sunassee, Kavitha, de Rosales, Rafael Torres Martin, Shanahan, Catherine, Blower, Philip J

“…The first (99m)Tc and (188)Re complexes containing two pendant bisphosphonate groups have been synthesised, based on the mononuclear M(v) nitride core with two…”
Get more information