Search Results - "Rosado, JA"

Saraf implication in the vascular remodeling by Martin Bornez, M, Rosado, JA, Ordonez, A, Smani, T

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TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure by Jardin, Isaac, Diez-Bello, Raquel, Lopez, Jose J, Redondo, Pedro C, Salido, Ginés M, Smani, Tarik, Rosado, Juan A

“…Transient receptor potential channels convey signaling information from a number of stimuli to a wide variety of cellular functions, mainly by inducing changes…”
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The Complex Role of Store Operated Calcium Entry Pathways and Related Proteins in the Function of Cardiac, Skeletal and Vascular Smooth Muscle Cells by Avila-Medina, Javier, Mayoral-Gonzalez, Isabel, Dominguez-Rodriguez, Alejandro, Gallardo-Castillo, Isabel, Ribas, Juan, Ordoñez, Antonio, Rosado, Juan A, Smani, Tarik

“…Cardiac, skeletal, and smooth muscle cells shared the common feature of contraction in response to different stimuli. Agonist-induced muscle's contraction is…”
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Acidic Ca2+ stores in platelets by Rosado, J.A

“…Abstract Changes in cytosolic free Ca2+ concentration play a pivotal role in the regulation of platelet functions, from secretion of autocrine and procoagulant…”
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Fluorescence-Based Measurements of the CRAC Channel Activity in Cell Populations by Redondo, Pedro C, Berna-Erro, Alejandro, Dionisio, Natalia, Rosado, Juan A

“…Cytosolic Ca plays an important role in cellular biology, and since its identification as a second messenger, a number of techniques and methods to analyze the…”
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Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted by Rosado, J A, Sage, S O

“…In the present study we have investigated the role of inositol 1,4, 5-trisphosphate (IP(3)), functional IP(3) receptors (IP(3)Rs) and the human homologue of…”
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Hydrogen peroxide and peroxynitrite enhance Ca2+ mobilization and aggregation in platelets from type 2 diabetic patients by Redondo, Pedro C, Jardin, Isaac, Hernández-Cruz, Juan M, Pariente, José A, Salido, Ginés M, Rosado, Juan A

“…Cytosolic Ca2+ mobilization, especially Ca2+ entry, is enhanced in platelets from type 2 diabetic individuals, which might result in platelet…”
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Ca2+ accumulation into acidic organelles mediated by Ca2+- and vacuolar H+-ATPases in human platelets by López, José J, Camello-Almaraz, Cristina, Pariente, José A, Salido, Ginés M, Rosado, Juan A

“…Most physiological agonists increase cytosolic free [Ca2+]c (cytosolic free Ca2+ concentration) to regulate a variety of cellular processes. How different…”
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A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets. Evidence for conformational coupling by Rosado, J A, Jenner, S, Sage, S O

“…The nature of the mechanism underlying store-mediated Ca(2+) entry has been investigated in human platelets through a combination of cytoskeletal…”
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Effect of hydrogen peroxide on Ca2+ mobilisation in human platelets through sulphydryl oxidation dependent and independent mechanisms by REDONDO, Pedro C, SALIDO, Ginés M, ROSADO, Juan A, PARIENTE, José A

“…Using Fura-2-loaded human platelets we studied the nature of the mechanisms involved in Ca2+ signalling mediated by H2O2. In a Ca2+-free medium, H2O2 (10…”
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Endogenously Expressed Trp1 Is Involved in Store-mediated Ca2+ Entry by Conformational Coupling in Human Platelets by Rosado, Juan A, Brownlow, Sharon L, Sage, Stewart O

“…Physical interaction between transient receptor potential (Trp) channels and inositol 1,4,5-trisphosphate receptors (IP 3 Rs) has been presented as a candidate…”
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Functional role of the calmodulin- and inositol 1,4,5-trisphosphate receptor-binding (CIRB) site of TRPC6 in human platelet activation by Dionisio, N., Albarran, L., Berna-Erro, A., Hernandez-Cruz, J.M., Salido, G.M., Rosado, J.A.

“…All identified mammalian TRPC channels show a C-terminal calmodulin (CaM)- and inositol 1,4,5-trisphosphate receptors (IP 3Rs)-binding (CIRB) site involved in…”
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Activation of store-mediated calcium entry by secretion-like coupling between the inositol 1,4,5-trisphosphate receptor type II and human transient receptor potential (hTrp1) channels in human platelets by Rosado, J A, Sage, S O

“…Physical coupling between inositol 1,4,5-trisphosphate (IP(3)) receptors and transient receptor potential (Trp) channels has been demonstrated in both…”
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A role for cofilin in the activation of store-operated calcium entry by de novo conformational coupling in human platelets by Redondo, Pedro C., Harper, Matthew T., Rosado, Juan A., Sage, Stewart O.

“…Store-operated Ca2+ entry (SOCE) is a major mechanism for Ca2+ influx in platelets and other cells. De novo conformational coupling between elements in the…”
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Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton by Rosado, J A, Sage, S O

“…We have investigated the mechanism of Ca(2+) entry into fura-2-loaded human platelets by preventing the prenylation of proteins such as small GTP-binding…”
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Store-operated Ca2+ entry: Vesicle fusion or reversible trafficking and de novo conformational coupling? by Rosado, Juan A., Redondo, Pedro C., Sage, Stewart O., Pariente, Jose A., Salido, Ginés M.

“…Store‐operated Ca2+ entry (SOCE), a mechanism regulated by the filling state of the intracellular Ca2+ stores, is a major pathway for Ca2+ influx. Hypotheses…”
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The inositol trisphosphate receptor antagonist 2-aminoethoxydiphenylborate (2-APB) blocks Ca2+ entry channels in human platelets: cautions for its use in studying Ca2+ influx by Diver, J.M., Sage, S.O., Rosado, J.A.

“…It has been reported that store-mediated Ca2+ entry (SMCE) in human platelets is likely to be mediated by a secretion-like coupling mechanism. Recently,…”
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The actin cytoskeleton in store-mediated calcium entry by Rosado, Juan A., Sage, Stewart O.

“…Store-mediated Ca 2+ entry is the main pathway for Ca 2+ influx in platelets and many other cells. Several hypotheses have considered both direct and indirect…”
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Tyrosine kinases activate store-mediated Ca2+ entry in human platelets through the reorganization of the actin cytoskeleton by Rosado, J A, Graves, D, Sage, S O

“…We have recently reported that store-mediated Ca(2+) entry in platelets is likely to be mediated by a reversible trafficking and coupling of the endoplasmic…”
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Dual effect of hydrogen peroxide on store-mediated calcium entry in human platelets by Redondo, Pedro C, Salido, Ginés M, Pariente, José A, Rosado, Juan A

“…Redox regulation is important for the modulation of cytosolic Ca 2+ concentration. Hence, we have investigated the effect of H 2O 2 on store-mediated Ca 2+…”
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