Search Results - "Rosa, M.C."
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Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment
Published in Current medicinal chemistry (01-01-2018)“…Dementia is characterized by the impairment of cognition and behavior of people over 65 years. Alzheimer's disease (AD) is the most prevalent neurodegenerative…”
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Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation
Published in Brazilian journal of medical and biological research (01-08-2012)“…Hepatocellular carcinoma (HCC) is the third highest cause of cancer death worldwide. In general, the disease is diagnosed at an advanced stage when potentially…”
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The use of quorum sensing to improve vaccine immune response
Published in Vaccine (17-12-2013)“…Highlights • We used the quorum sensing effect to improve vaccine efficacy. • We examine changes in the level of LT toxin and F4 fimbriae expression on ETEC E…”
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“Cell ELISA” como ferramenta auxiliar no controle da adenite equina
Published in Arquivo brasileiro de medicina veterinária e zootecnia (01-01-2018)“…RESUMO Este trabalho relata o desenvolvimento e a avaliação de um ensaio imunoenzimático (ELISA) como ferramenta auxiliar no controle da adenite equina. Foi…”
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A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
Published in Journal of medicinal chemistry (12-09-2019)“…Inhibiting the protein–protein interaction (PPI) between the transcription factor Nrf2 and its repressor protein Keap1 has emerged as a promising strategy to…”
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Biological importance of γ-glutamyl-S-methylcysteine of kidney bean ( Phaseolus vulgaris L.)
Published in Food chemistry (01-05-2001)“…The effects of S-methyl-L-cysteine (SMC) on growth and food intake by rats were investigated and in vivo absorption studies of…”
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Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds
Published in Journal of medicinal chemistry (22-04-2021)“…Targeting the protein–protein interaction (PPI) between nuclear factor erythroid 2-related factor 2 (Nrf2) and Kelch-like ECH-associated protein 1 (Keap1) is a…”
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1688P Impact of immunotherapy on the risk of thromboembolic disease in patients with melanoma
Published in Annals of oncology (01-09-2021)Get full text
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1691P Thromboembolic disease and immunotherapy in lung cancer
Published in Annals of oncology (01-09-2021)Get full text
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Cluster analysis identifies patients at risk of catheter-associated urinary tract infections in intensive care units: findings from the SPIN-UTI Network
Published in The Journal of hospital infection (01-01-2021)“…Although preventive strategies have been proposed against catheter-associated urinary tract infections (CAUTIs) in intensive care units (ICUs), more efforts…”
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Antioxidant activity of chlorophylls and their derivatives
Published in Food research international (01-01-2005)“…The antioxidant activity of six natural isolated chlorophyll derivatives and Cu-chlorophyllin was investigated by measuring their protective action against…”
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Epidemic of Postsurgical Infections Caused by Mycobacterium massiliense
Published in Journal of Clinical Microbiology (01-07-2009)“…An epidemic of infections after video-assisted surgery (1,051 possible cases) caused by rapidly growing mycobacteria (RGM) and involving 63 hospitals in the…”
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“Cell ELISA” como ferramenta auxiliar no controle da adenite equina
Published in Arquivo brasileiro de medicina veterinária e zootecnia (01-01-2018)“…RESUMO Este trabalho relata o desenvolvimento e a avaliação de um ensaio imunoenzimático (ELISA) como ferramenta auxiliar no controle da adenite equina. Foi…”
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Potential inhibitors of the enzyme acetylcholinesterase and juvenile hormone with insecticidal activity: study of the binding mode via docking and molecular dynamics simulations
Published in Journal of biomolecular structure & dynamics (01-11-2020)“…Models validation in QSAR, pharmacophore, docking and others can ensure the accuracy and reliability of future predictions in design and selection of molecules…”
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Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation
Published in Brazilian journal of medical and biological research (01-08-2012)“…Hepatocellular carcinoma (HCC) is the third highest cause of cancer death worldwide. In general, the disease is diagnosed at an advanced stage when potentially…”
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Non-Synergistic UV-A Photocatalytic Degradation of Estrogens by Nano-TiO2 Supported on Activated Carbon
Published in Journal of the Brazilian Chemical Society (01-04-2017)“…Many studies have reported significant improvements in the photocatalytic degradation capacity of TiO2 immobilized in carbonaceous materials, mainly due to a…”
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Computational design of new protein kinase 2 inhibitors for the treatment of inflammatory diseases using QSAR, pharmacophore-structure-based virtual screening, and molecular dynamics
Published in Journal of molecular modeling (01-09-2018)“…Receptor-interacting protein kinase 2 (RIPK2) plays an essential role in autoimmune response and is suggested as a target for inflammatory diseases. A…”
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In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity
Published in Molecules (Basel, Switzerland) (15-04-2019)“…Inflammation is a complex reaction involving cellular and molecular components and an unspecific response to a specific aggression. The use of scientific and…”
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Increased stimulation threshold in a patient with autoimmune disease: successful management with oral prednisolone and azathioprine
Published in Europace (London, England) (01-04-2009)“…We report a patient with a systemic vasculitis and heart involvement with complete atrio-ventricular block. After pacemaker implantation, the stimulation…”
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