Search Results - "Ros, Robert"
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Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs
Published in Acta biomaterialia (01-09-2016)“…[Display omitted] The development of advanced biomaterials is a crucial step to enhance the efficacy of tissue engineering strategies for treatment of…”
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A comparison of methods to assess cell mechanical properties
Published in Nature methods (01-07-2018)“…The mechanical properties of cells influence their cellular and subcellular functions, including cell adhesion, migration, polarization, and differentiation,…”
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A three dimensional micropatterned tumor model for breast cancer cell migration studies
Published in Biomaterials (01-03-2016)“…Abstract Breast cancer cell invasion is a highly orchestrated process driven by a myriad of complex microenvironmental stimuli, making it difficult to isolate…”
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4
Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions
Published in The Journal of cell biology (02-12-2019)“…The mechanical properties of a cell's microenvironment influence many aspects of cellular behavior, including cell migration. Durotaxis, the migration toward…”
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Type IV Pili-Independent Photocurrent Production by the Cyanobacterium Synechocystis sp. PCC 6803
Published in Frontiers in microbiology (25-06-2020)“…Biophotovoltaic devices utilize photosynthetic organisms such as the model cyanobacterium sp. PCC 6803 ( ) to generate current for power or hydrogen production…”
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Mismatch in Mechanical and Adhesive Properties Induces Pulsating Cancer Cell Migration in Epithelial Monolayer
Published in Biophysical journal (20-06-2012)“…The mechanical and adhesive properties of cancer cells significantly change during tumor progression. Here we assess the functional consequences of mismatched…”
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The Role of Desmoplasia and Stromal Fibroblasts on Anti-cancer Drug Resistance in a Microengineered Tumor Model
Published in Cellular and molecular bioengineering (01-10-2018)“…Introduction Cancer associated fibroblasts (CAFs) are known to participate in anti-cancer drug resistance by upregulating desmoplasia and pro-survival…”
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Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices
Published in Proceedings of the National Academy of Sciences - PNAS (08-11-2011)“…Medical implants, like cardiovascular devices, improve the quality of life for countless individuals but may become infected with bacteria like Staphylococcus…”
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Poly(oxyethylene) Based Surface Coatings for Poly(dimethylsiloxane) Microchannels
Published in Langmuir (02-08-2005)“…Control of surface properties in microfluidic systems is an indispensable prerequisite for successful bioanalytical applications. Poly(dimethylsiloxane) (PDMS)…”
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10
Photochemical Single-Molecule Affinity Switch
Published in Journal of the American Chemical Society (14-02-2007)“…Manipulation and control at the molecular level is a prerequisite for future nanomachines and nanodevices. In order to build a bistable molecular affinity…”
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Transparent Gold as a Platform for Adsorbed Protein Spectroelectrochemistry: Investigation of Cytochrome c and Azurin
Published in Langmuir (03-04-2012)“…The majority of protein spectroelectrochemical methods utilize a diffusing, chemical mediator to exchange electrons between the electrode and the protein. In…”
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12
Unbinding Forces of Single Antibody-Antigen Complexes Correlate with Their Thermal Dissociation Rates
Published in Proceedings of the National Academy of Sciences - PNAS (29-08-2000)“…Point mutants of three unrelated antifluorescein antibodies were constructed to obtain nine different single-chain Fv fragments, whose on-rates, off-rates, and…”
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Antigen Binding Forces of Individually Addressed Single-Chain Fv Antibody Molecules
Published in Proceedings of the National Academy of Sciences - PNAS (23-06-1998)“…Antibody single-chain Fv fragment (scFv) molecules that are specific for fluorescein have been engineered with a C-terminal cysteine for a directed…”
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Specific binding of the regulatory protein ExpG to promoter regions of the galactoglucan biosynthesis gene cluster of Sinorhizobium meliloti - a combined molecular biology and force spectroscopy investigation
Published in Journal of structural biology (01-08-2003)“…Specific protein–DNA interaction is fundamental for all aspects of gene transcription. We focus on a regulatory DNA-binding protein in the Gram-negative soil…”
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Reverse Engineering of an Affinity-Switchable Molecular Interaction Characterized by Atomic Force Microscopy Single-Molecule Force Spectroscopy
Published in Langmuir (19-02-2008)“…Tunable and switchable interaction between molecules is a key for regulation and control of cellular processes. The translation of the underlying…”
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The surface (S)-layer gene cspB of Corynebacterium glutamicum is transcriptionally activated by a LuxR-type regulator and located on a 6 kb genomic island absent from the type strain ATCC 13032
Published in Microbiology (Society for General Microbiology) (01-04-2006)“…1 Lehrstuhl für Genetik, Fakultät für Biologie, Universität Bielefeld, Universitätsstraße 25, D-33615 Bielefeld, Germany 2 Institut für Genomforschung, Centrum…”
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Proteoglycan Mechanics Studied by Single-molecule Force Spectroscopy of Allotypic Cell Adhesion Glycans
Published in The Journal of biological chemistry (03-03-2006)“…Early Metazoans had to evolve the first cell adhesion system addressed to maintaining stable interactions between cells constituting different individuals. As…”
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On-Line Detection of Nonspecific Protein Adsorption at Artificial Surfaces
Published in Analytical chemistry (Washington) (15-08-1997)“…A detailed understanding of the interaction of proteins with artificial surfaces is essential for many applications in medicine and biochemistry. The affinity…”
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Correlating confocal microscopy and atomic force indentation reveals metastatic cancer cells stiffen during invasion into collagen I matrices
Published in Scientific reports (27-01-2016)“…Mechanical interactions between cells and their microenvironment dictate cell phenotype and behavior, calling for cell mechanics measurements in…”
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Single molecule force spectroscopy on ligand–DNA complexes: from molecular binding mechanisms to biosensor applications
Published in Journal of Biotechnology (26-08-2004)“…Recent developments in single molecule force spectroscopy (SMFS) allow direct observation and measurements of forces that hold protein–DNA complexes together…”
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