Search Results - "Roqueiro, Damian"

Genome-wide analysis of local chromatin packing in Arabidopsis thaliana by Wang, Congmao, Liu, Chang, Roqueiro, Damian, Grimm, Dominik, Schwab, Rebecca, Becker, Claude, Lanz, Christa, Weigel, Detlef

“…The spatial arrangement of interphase chromosomes in the nucleus is important for gene expression and genome function in animals and in plants. The recently…”
Get full text

easyGWAS: A Cloud-Based Platform for Comparing the Results of Genome-Wide Association Studies by Grimm, Dominik G., Roqueiro, Damian, Salomé, Patrice A., Kleeberger, Stefan, Greshake, Bastian, Zhu, Wangsheng, Liu, Chang, Lippert, Christoph, Stegle, Oliver, Schölkopf, Bernhard, Weigel, Detlef, Borgwardt, Karsten M.

“…The ever-growing availability of high-quality genotypes for a multitude of species has enabled researchers to explore the underlying genetic architecture of…”
Get full text

Ensemble learning and ground-truth validation of synaptic connectivity inferred from spike trains by Donner, Christian, Bartram, Julian, Hornauer, Philipp, Kim, Taehoon, Roqueiro, Damian, Hierlemann, Andreas, Obozinski, Guillaume, Schröter, Manuel

“…Probing the architecture of neuronal circuits and the principles that underlie their functional organization remains an important challenge of modern…”
Get full text

Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis by Dyson, Matthew T, Roqueiro, Damian, Monsivais, Diana, Ercan, C Mutlu, Pavone, Mary Ellen, Brooks, David C, Kakinuma, Toshiyuki, Ono, Masanori, Jafari, Nadereh, Dai, Yang, Bulun, Serdar E

“…Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is…”
Get full text

CASMAP: detection of statistically significant combinations of SNPs in association mapping by Llinares-López, Felipe, Papaxanthos, Laetitia, Roqueiro, Damian, Bodenham, Dean, Borgwardt, Karsten

“…Abstract Summary Combinatorial association mapping aims to assess the statistical association of higher-order interactions of genetic markers with a phenotype…”
Get full text

Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial αvβ3 integrin expression by Joshi, Niraj R, Kohan-Ghadr, Hamid-Reza, Roqueiro, Damian S, Yoo, Jung Yoon, Fru, Karenne, Hestermann, Eli, Yuan, Lingwen, Ho, Shuk-Mei, Jeong, Jae-Wook, Young, Steven L, Lessey, Bruce A, Fazleabas, Asgerally T

“…Abstract About 40% of women with infertility and 70% of women with pelvic pain suffer from endometriosis. The pregnancy rate in women undergoing IVF with low…”
Get full text

Kernel conditional clustering and kernel conditional semi-supervised learning by He, Xiao, Gumbsch, Thomas, Roqueiro, Damian, Borgwardt, Karsten

“…The results of clustering are often affected by covariates that are independent of the clusters one would like to discover. Traditionally, alternative…”
Get full text

Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse by Afshar, Yalda, Jeong, Jae‐Wook, Roqueiro, Damian, DeMayo, Franco, Lydon, John, Radtke, Freddy, Radnor, Rachel, Miele, Lucio, Fazleabas, Asgerally

“…ABSTRACT Uterine receptivity implies a dialogue between the hormonally primed maternal endometrium and the free‐floating blastocyst. Endometrial stromal cells…”
Get full text

Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire by Montefiori, Lindsey, Wuerffel, Robert, Roqueiro, Damian, Lajoie, Bryan, Guo, Changying, Gerasimova, Tatiana, De, Supriyo, Wood, William, Becker, Kevin G., Dekker, Job, Liang, Jie, Sen, Ranjan, Kenter, Amy L.

“…Early B cell development is characterized by large-scale Igh locus contraction prior to V(D)J recombination to facilitate a highly diverse Ig repertoire…”
Get full text

Predicting in vitro single-neuron firing rates upon pharmacological perturbation using Graph Neural Networks by Kim, Taehoon, Chen, Dexiong, Hornauer, Philipp, Emmenegger, Vishalini, Bartram, Julian, Ronchi, Silvia, Hierlemann, Andreas, Schröter, Manuel, Roqueiro, Damian

“…Modern Graph Neural Networks (GNNs) provide opportunities to study the determinants underlying the complex activity patterns of biological neuronal networks…”
Get full text

Genome-wide progesterone receptor binding: cell type-specific and shared mechanisms in T47D breast cancer cells and primary leiomyoma cells by Yin, Ping, Roqueiro, Damian, Huang, Lei, Owen, Jonas K, Xie, Anna, Navarro, Antonia, Monsivais, Diana, Coon, 5th, John S, Kim, J Julie, Dai, Yang, Bulun, Serdar E

“…Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the…”
Get full text

A Local Genetic Algorithm for the Identification of Condition-Specific MicroRNA-Gene Modules by Mu, Wenbo, Dai, Yang, Roqueiro, Damian

“…Transcription factor and microRNA are two types of key regulators of gene expression. Their regulatory mechanisms are highly complex. In this study, we propose…”
Get full text

Accurate and adaptive imputation of summary statistics in mixed-ethnicity cohorts by Togninalli, Matteo, Roqueiro, Damian, Borgwardt, Karsten M

“…Abstract Motivation Methods based on summary statistics obtained from genome-wide association studies have gained considerable interest in genetics due to the…”
Get full text

Association mapping in biomedical time series via statistically significant shapelet mining by Bock, Christian, Gumbsch, Thomas, Moor, Michael, Rieck, Bastian, Roqueiro, Damian, Borgwardt, Karsten

“…Abstract Motivation Most modern intensive care units record the physiological and vital signs of patients. These data can be used to extract signatures,…”
Get full text

Spatial and single-cell transcriptomics provide insights into the complex inflammatory cell network in atopic dermatitis by Mitamura, Yasutaka, Reiger, Matthias, Kim, Juno, Xiao, Yi, Zhakparov, Damir, Bärenfaller, Katja, Brunner, Patrick M., Roqueiro, Damian, Traidl-Hoffmannn, Claudia, Akdis, Cezmi

Get full text

Genome-wide genetic heterogeneity discovery with categorical covariates by Llinares-López, Felipe, Papaxanthos, Laetitia, Bodenham, Dean, Roqueiro, Damian, Borgwardt, Karsten

“…Genetic heterogeneity is the phenomenon that distinct genetic variants may give rise to the same phenotype. The recently introduced algorithm Fast Automatic…”
Get full text

Spatial transcriptomics combined with single‐cell RNA‐sequencing unravels the complex inflammatory cell network in atopic dermatitis by Mitamura, Yasutaka, Reiger, Matthias, Kim, Juno, Xiao, Yi, Zhakparov, Damir, Tan, Ge, Rückert, Beate, Rinaldi, Arturo O., Baerenfaller, Katja, Akdis, Mübeccel, Brüggen, Marie‐Charlotte, Nadeau, Kari C., Brunner, Patrick M., Roqueiro, Damian, Traidl‐Hoffmann, Claudia, Akdis, Cezmi A.

“…Background Atopic dermatitis (AD) is the most common chronic inflammatory skin disease with complex pathogenesis for which the cellular and molecular crosstalk…”
Get full text

SigMod: an exact and efficient method to identify a strongly interconnected disease-associated module in a gene network by Liu, Yuanlong, Brossard, Myriam, Roqueiro, Damian, Margaritte-Jeannin, Patricia, Sarnowski, Chloé, Bouzigon, Emmanuelle, Demenais, Florence

“…Apart from single marker-based tests classically used in genome-wide association studies (GWAS), network-assisted analysis has become a promising approach to…”
Get full text

Changes in Eutopic Endometrial Gene Expression During the Progression of Experimental Endometriosis in the Baboon, Papio Anubis by AFSHAR, Yalda, HASTINGS, Julie, ROQUEIRO, Damian, JEONG, Jae-Wook, GIUDICE, Linda C, FAZLEABAS, Asgerally T

“…Endometriosis is associated with aberrant gene expression in the eutopic endometrium of women with disease. To determine if the development of endometriotic…”
Get full text

DeePhys: A machine learning–assisted platform for electrophysiological phenotyping of human neuronal networks by Hornauer, Philipp, Prack, Gustavo, Anastasi, Nadia, Ronchi, Silvia, Kim, Taehoon, Donner, Christian, Fiscella, Michele, Borgwardt, Karsten, Taylor, Verdon, Jagasia, Ravi, Roqueiro, Damian, Hierlemann, Andreas, Schröter, Manuel

“…Reproducible functional assays to study in vitro neuronal networks represent an important cornerstone in the quest to develop physiologically relevant cellular…”
Get full text