Search Results - "Roos, I A"

The binding of binuclear platinum(II)-terpyridine complexes to DNA by McFadyen, W D, Wakelin, L P, Roos, I A, Hillcoat, B L

“…The binding of platinum (II)-terpyridine complexes to DNA was studied by using equilibrium dialysis. Optical absorption methods were used to measure the…”
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Binuclear platinum (II)-terpyridine complexes. A new class of bifunctional DNA-intercalating agent by McFadyen, W D, Wakelin, L P, Roos, I A, Hillcoat, B L

“…A series of binuclear DNA-binding ligands was prepared by linking two (2,2':6',2"-terpyridine)platinum(II) moieties via alpha omega-dithiols of the type…”
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Interaction of platinum compounds with dinucleotides by Roos, I. A. G, Thomson, A. J, Mansy, S

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A peculiar toxicity manifested by platinum(II)amines in rats: gastric distension after intraperitoneal administration by Roos, I A, Fairlie, D P, Whitehouse, M W

“…Metoclopramide i.p. reduces the gastric distension consistently seen in rats given cisplatin i.p. at effective immunosuppressant doses (6 mg/kg). Many other…”
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cis-Bis(pyridine)platinum(II) organoamides with unexpected growth inhibition properties and antitumor activity by Webster, Lorraine K, Deacon, Glen B, Buxton, David P, Hillcoat, Brian L, James, Alison M, Roos, Ian A. G, Thomson, Robin J, Wakelin, Laurence P. G, Williams, Tracey L

“…The platinum(II) organoamides [Pt(NRCH2)2L2] (L = pyridine (py), R = p-HC6F4, C6F5,p-IC6F4,p-CIC6F4,p-C6F5C6F4; L = 4-methylpyridine, R = p-HC6F4) and…”
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Metallothionein induction in mouse tissues by cis-dichlorodiammineplatinum(II) and its hydrolysis products by Farnworth, P G, Hillcoat, B L, Roos, I A

“…cis-Dichlorodiammineplatinum(II) (cis-DDP) doubled the amount of metallothioneins (MTs) in the livers and kidneys of BALB/c mice when injected i.p. in a single…”
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Interaction of phenylthiolato-(2,2',2"-terpyridine)platinum(II) cation with DNA by Wakelin, L P, McFadyen, W D, Walpole, A, Roos, I A

“…The interaction between a novel aromatic thiolato derivative from the family of DNA-intercalating platinum complexes,…”
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Collection and analysis of kinetic data from a stopped-flow spectrophotometer using a microcomputer by Roos, I A, Wakelin, L P, Hakkennes, J, Coles, J

“…A method of interfacing an inexpensive microcomputer to a stopped-flow kinetics spectrophotometer is described. It allows software-selectable sampling…”
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Development of a murine gastric distension model for testing the emetic potential of new drugs and efficacy of antiemetics by Olver, I N, Roos, I A, Thomas, K, Hillcoat, B L

“…A small animal model for emesis would allow preclinical testing of antiemetics and new drugs. Mice treated with cisplatinum develop stomachs distended with…”
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Intracellular DNA damage produced by a series of diacridines by Roos, I A, Wakelin, L P, Henry, S J

“…The intracellular DNA damage produced by a series of diacridines after a 2 h pulse treatment of L1210 cells in culture was investigated by using the…”
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Version Variation Visualization (VVV): Case Studies on the Hebrew Haggadah in English by Cheesman, Tom, Roos, Avraham

“…The ‘Version Variation Visualization’ project has developed online tools to support comparative, algorithm-assisted investigations of a corpus of multiple…”
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Racial Identity, Reparations, and Modern Views of Justice Concerning Slavery by Reichelmann, Ashley V, Roos, J Micah, Hughes, Michael

“…Public opinion polls frequently demonstrate that the American debate on reparations for slavery falls along racial lines. However, less attention has been paid…”
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Activity of platinum(II) intercalating agents against murine leukemia L1210 by McFadyen, W. David, Wakelin, Laurence P. G, Roos, Ian A. G, Leopold, Virginia A

“…Four series of intercalating, square-planar Pt(II) complexes derived from the ligands 2,2'-bipyridine, 2,2':6',2"-terpyridine, 1,10-phenanthroline, and…”
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The interaction of an anti-tumour platinum complex with DNA by Roos, I A

“…The interaction of the anti-tumour active cis platinum (II) complexes with DNA has been investigated using dichloro(ethylenediamine)platinum(II) and E. coli…”
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Activity of platinum (II) intercalating agents against murine leukemia L 1210 by MCFAYDEN, W. D, WAKELIN, L. P. G, ROOS, I. A. G, LEOPOLD, V. A

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Interrelations between anti-tumour activity, DNA breakage, and DNA binding kinetics for 9-aminoacridinecarboxamide anti-tumour agents by Denny, W A, Roos, I A, Wakelin, L P

“…For a series of 9-aminoacridinecarboxamides, anti-tumour activity in vivo and cytotoxicity in vitro are correlated directly with the ability of the compounds…”
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Combined actions of 5-fluorouracil and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea on human colonic carcinoma cells in vitro by Sutton, J E, Roos, I A, Hillcoat, B L

“…Two lines of human colonic carcinoma cells have different sensitivities to 5-fluorouracil and 1-(2-chlorethyl)-3-(4-methylcyclohexyl)-1-nitrosourea…”
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Mass spectrometric studies of the interaction of platinum complexes with nucleoside analogues by Roos, I A, Thomson, A J, Eagles, J

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Thyrotropin Receptor Autoantibody Assessment in Thyroid Eye Disease: Does the Assay Type Matter? by Malik Moledina, Jonathan Roos, Rachna Murthy

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Reproductive biology of 58 fish species around La Réunion Island (Western Indian Ocean): first sexual maturity and spawning period by Kelig Mahe, Julien Taconet, Blandine Brisset, Claire Gentil, Yoann Aumond, Hugues Evano, Louis Wambergue, Romain Elleboode, Tevamie Rungassamie, David Roos

“…Background: The biological information of fish, which include reproduction, is the prerequisite and the basis for the assessment of fisheries. Methods: The aim…”
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