Search Results - "Rooke, Jessica L"
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Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth
Published in PLoS genetics (23-12-2021)“…The cell envelope is essential for viability in all domains of life. It retains enzymes and substrates within a confined space while providing a protective…”
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Genome-wide fitness analysis of Salmonella enterica reveals aroA mutants are attenuated due to iron restriction in vitro
Published in mBio (17-09-2024)“…is a globally disseminated pathogen that is the cause of over 100 million infections per year. The resulting diseases are dependent upon host susceptibility…”
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Type 5 secretion system antigens as vaccines against Gram-negative bacterial infections
Published in npj vaccines (01-09-2024)“…Infections caused by Gram-negative bacteria are leading causes of mortality worldwide. Due to the rise in antibiotic resistant strains, there is a desperate…”
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BamA and BamD Are Essential for the Secretion of Trimeric Autotransporter Adhesins
Published in Frontiers in microbiology (23-02-2021)“…The BAM complex in is composed of five proteins, BamA-E. BamA and BamD are essential for cell viability and are required for the assembly of β-barrel outer…”
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Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum
Published in eLife (27-08-2024)“…is a global public health concern due to the rising myriad of hypervirulent and multidrug-resistant clones both alarmingly associated with high mortality. The…”
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