Search Results - "Roohvand, Farzin"

Rotavirus VP6: involvement in immunogenicity, adjuvant activity, and use as a vector for heterologous peptides, drug delivery, and production of nano-biomaterials by Shoja, Zabihollah, Jalilvand, Somayeh, Latifi, Tayebeh, Roohvand, Farzin

“…The first-generation, live attenuated rotavirus (RV) vaccines, such as RotaTeq and Rotarix, were successful in reducing the number of RV-induced acute…”
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Cross talk between alcohol-induced oxidative stress and HCV replication by Sobhanimonfared, Fatemeh, Bamdad, Taravat, Roohvand, Farzin

“…Alcohol consumption exacerbates the pathogenesis of hepatitis C virus (HCV) infection and aggravates disease consequences in alcohol‐abusing patients. Although…”
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The Role of 3'UTR of RNA Viruses on mRNA Stability and Translation Enhancement by Rasekhian, Mahsa, Roohvand, Farzin, Habtemariam, Solomon, Marzbany, Marzieh, Kazemimanesh, Monireh

“…The central dogma of molecular biology explains the flow of genetic information from DNA to functional products such as proteins. In most cases, a linear…”
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Circulating rotavirus strains in children with acute gastroenteritis in Iran, 1986 to 2023 and their genetic/antigenic divergence compared to approved vaccines strains (Rotarix, RotaTeq, ROTAVAC, ROTASIIL) before mass vaccination: Clues for vaccination policy makers by Jalilvand, Somayeh, Latifi, Tayebeh, Kachooei, Atefeh, Mirhoseinian, Mahtab, Hoseini-Fakhr, Somayeh-Sadat, Behnezhad, Farzane, Roohvand, Farzin, Shoja, Zabihollah

“…•Overall, the most common genotypes or combinations were G1 and P[8], or G1P[8].•From 2015 to 2023, intermittent peaks of genotypes G3P[8] and G9P[8] were…”
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Alum and a TLR7 agonist combined with built-in TLR4 and 5 agonists synergistically enhance immune responses against HPV RG1 epitope by Mashhadi Abolghasem Shirazi, Maryam, Sadat, Seyed Mehdi, Haghighat, Setareh, Roohvand, Farzin, Arashkia, Arash

“…To relieve the limitations of the human papillomavirus (HPV) vaccines based on L1 capsid protein, vaccine formulations based on RG1 epitope of HPV L2 using…”
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Taguchi array optimization of the reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for sensitive and rapid detection of dengue virus serotype 2 by Shoushtari, Mohammad, Salehi-Vaziri, Mostafa, Roohvand, Farzin, Arashkia, Arash, Jalali, Tahmineh, Azadmanesh, Kayhan

“…Objectives Serotype 2 of dengue virus (DENV-2) is the most prevalent cause of dengue fevers. In this study, the C-prM gene was used for specific detection of…”
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Adenovirus vector-based vaccines as forefront approaches in fighting the battle against flaviviruses by Shoushtari, Mohammad, Roohvand, Farzin, Salehi-Vaziri, Mostafa, Arashkia, Arash, Bakhshi, Hasan, Azadmanesh, Kayhan

“…Flaviviruses are arthropod-borne viruses (arboviruses) that have been recently considered among the significant public health problems in defined geographical…”
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Bi/tri-specific antibodies (HN-Fc-CD16 and HN-Fc-IL-15-CD16) cross-linking natural killer (NK)-CD16 and Newcastle Disease Virus (NDV)-HN, enhanced NK activation for cancer immunotherapy by Bahrololoumi Shapourabadi, Mina, Momburg, Frank, Roohvand, Farzin, Jarahian, Mostafa, Mohajel, Nasir, Arashkia, Arash, Hajari Taheri, Fatemeh, Abbasalipour, Maryam, Azadmanesh, Kayhan

“…•The bs-Ab (HN-Fc-CD16) and ts-Ab (HN-Fc-IL15-CD16) were properly constructed.•In silico and computational analyses indicated proper exposure of Abs in…”
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In Vitro Anti-Viral Effects of Small Heat Shock Proteins 20 and 27: A Novel Therapeutic Approach by Vahabpour, Rouhollah, Soleymani, Sepehr, Roohvand, Farzin, Zabihollahi, Rezvan, Bolhassani, Azam

“…The protective effects of heat shock proteins (Hsps) were studied in some infectious and non-infectious diseases, but their specificity was slightly known in…”
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Oral Administration of Recombinant Saccharomyces boulardii Expressing Ovalbumin-CPE Fusion Protein Induces Antibody Response in Mice by Bagherpour, Ghasem, Ghasemi, Hosnie, Zand, Bahare, Zarei, Najmeh, Roohvand, Farzin, Ardakani, Esmat M, Azizi, Mohammad, Khalaj, Vahid

“…, a subspecies of , is a well-known eukaryotic probiotic with many benefits for human health. In the present study, a recombinant strain of was prepared to use…”
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BacMam virus-based surface display for HCV E2 glycoprotein induces strong cross-neutralizing antibodies and cellular immune responses in vaccinated mice by Kord, Ebrahim, Roohvand, Farzin, Dubuisson, Jean, Vausselin, Thibaut, Nasr Azadani, Hosein, Keshavarz, Abolfazl, Nejati, Ahmad, Samimi-Rad, Katayoun

“…Despite recent advancements, limitations in the treatment and control of hepatitis C virus (HCV) infection reprioritized the studies for invention of an…”
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Co-administration of 2'3'-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model by Dorostkar, Fariba, Arashkia, Arash, Roohvand, Farzin, Shoja, Zabihollah, Navari, Mohsen, Mashhadi Abolghasem Shirazi, Maryam, Shahosseini, Zahra, Farahmand, Mohammad, Shams Nosrati, Mohammad Sadegh, Jalilvand, Somayeh

“…Persistent infection with high-risk genotypes of human papillomavirus (HPV) is the leading cause of cervical cancer. The HPV oncoprotein E7 is constitutively…”
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Fusion of HBsAg and prime/boosting augment Th1 and CTL responses to HCV polytope DNA vaccine by Memarnejadian, Arash, Roohvand, Farzin

“…Correlation of hepatitis C virus (HCV) spontaneous resolution with Th1 and CD8 +CTL responses during natural infection implies the potentiality of…”
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Lipoprotein lipase inhibits hepatitis C virus (HCV) infection by blocking virus cell entry by Maillard, Patrick, Walic, Marine, Meuleman, Philip, Roohvand, Farzin, Huby, Thierry, Le Goff, Wilfried, Leroux-Roels, Geert, Pécheur, Eve-Isabelle, Budkowska, Agata

“…A distinctive feature of HCV is that its life cycle depends on lipoprotein metabolism. Viral morphogenesis and secretion follow the very low-density…”
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Anti-viral Effects of Superpositively Charged Mutant of Green Fluorescent Protein by Vahabpour, Rouhollah, Basimi, Parya, Roohvand, Farzin, Asadi, Hassan, Irani, Gholnaz M, Zabihollahi, Rezvan, Bolhassani, Azam

“…Supercharged GFP proteins were known as effective carriers for delivery of macromolecules into eukaryotic cells as well as fluorescent fusion tags for in vitro…”
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Contribution of Streptokinase-Domains from Groups G and A (SK2a) Streptococci in Amidolytic/Proteolytic Activities and Fibrin-Dependent Plasminogen activation: A Domain-Exchange Study by Rafipour, Maryam, Keramati, Malihe, Aslani, Mohammad Mehdi, Arashkia, Arash, Roohvand, Farzin

“…Streptokinase (SK), a heterogeneous plasminogen activator (PA) protein from groups A, C, and G streptococci (GAS, GCS, GGS, respectively) contains three…”
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Affinity Based Nano-Magnetic Particles for Purification of Recombinant Proteins in Form of Inclusion Body by Seyedinkhorasani, Masoud, Ahangari Cohan, Reza, Taghavi Fardood, Saeid, Roohvand, Farzin, Norouzian, Dariush, Keramati, Malihe

“…Protein purification is the most complicated issue in the downstream processes of recombinant protein production; therefore, improved selective purification…”
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The β‐domain of streptokinase affects several functionalities, including specific/proteolytic activity kinetics by Rafipour, Maryam, Keramati, Malihe, Aslani, Mohammad Mehdi, Arashkia, Arash, Roohvand, Farzin

“…Streptokinase (SK) is a plasminogen activator which converts inactive plasminogen (Pg) to active plasmin (Pm), which cleaves fibrin clots. SK secreted by…”
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A Dual-Type L2 11-88 Peptide from HPV Types 16/18 Formulated in Montanide ISA 720 Induced Strong and Balanced Th1/Th2 Immune Responses, Associated with High Titers of Broad Spectrum Cross-Reactive Antibodies in Vaccinated Mice by Roohvand, Farzin, Nasimi, Maryam, Golkar, Majid, Arashkia, Arash, Motavalli Khiavi, Farhad, Azadmanesh, Kayhan

“…E. coli-derived concatenated, multitype L2-conserved epitopes of human papillomavirus (HPV) L2 protein might represent a less expensive and pan-type vaccine…”
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HCV Core/NS3 Protein Immunization with "N-Terminal Heat Shock gp96 Protein (rNT (gp96))" Induced Strong and Sustained Th1-Type Cytokines in Immunized Mice by Hajikhezri, Zamaneh, Roohvand, Farzin, Maleki, Monireh, Shahmahmoodi, Shohreh, Amirzargar, Ali Akbar, Keshavarz, Abolfazl, Seyed, Negar, Farahmand, Mohammad, Samimi-Rad, Katayoun

“…Feeble cellular responses induced by T cell-based vaccines are a major challenge for the development of an effective vaccine against Hepatitis C virus (HCV)…”
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