Search Results - "Roohbakhsh, Ali"
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Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases
Published in Life sciences (1973) (01-03-2015)“…Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species that have various biological properties, particularly those for the…”
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Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin
Published in Life sciences (1973) (15-09-2015)“…Many plants produce flavonoids as secondary metabolites. These organic compounds may be involved in the defense against plant-threatening factors, such as…”
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Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review
Published in Biomedicine & pharmacotherapy (01-07-2017)“…Graphical abstract…”
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Glycyrrhetinic Acid and Its Derivatives: Anti-Cancer and Cancer Chemopreventive Properties, Mechanisms of Action and Structure- Cytotoxic Activity Relationship
Published in Current medicinal chemistry (01-01-2016)“…The anti-cancer properties of liquorice have been attributed, at least in part, to glycyrrhizin (GL). However, GL is not directly absorbed through the…”
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Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin — A mini-review
Published in Life sciences (1973) (15-09-2014)“…Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species that have various biological properties. Over the past decade, a…”
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MicroRNAs regulate mitochondrial apoptotic pathway in myocardial ischemia-reperfusion-injury
Published in Biomedicine & pharmacotherapy (01-12-2016)“…Abstract MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene regulators. They are involved in the pathogenesis of different…”
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The role of orphan G protein-coupled receptors in the modulation of pain: A review
Published in Life sciences (1973) (01-11-2018)“…G protein-coupled receptors (GPCRs) comprise a large number of receptors. Orphan GPCRs are divided into six families. These groups contain orphan receptors for…”
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Effects of telmisartan on metabolic syndrome components: a comprehensive review
Published in Biomedicine & pharmacotherapy (01-02-2024)“…Telmisartan is an antagonist of the angiotensin II receptor used in the management of hypertension (alone or in combination with other antihypertensive agents…”
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Zataria multiflora and Pioglitazone Affect Systemic Inflammation and Oxidative Stress Induced by Inhaled Paraquat in Rats
Published in Mediators of inflammation (2021)“…The effects of Zataria multiflora (Z. multiflora) and pioglitazone (a PPAR-γ agonist) alone and in combination, on systemic inflammation and oxidative stress…”
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Central administration of GPR55 receptor agonist and antagonist modulates anxiety-related behaviors in rats
Published in Fundamental & clinical pharmacology (01-04-2015)“…G‐protein‐coupled receptor 55 (GPR55) has been proposed as an atypical cannabinoid receptor, which is activated by lysophosphatidylinositols and some synthetic…”
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Dietary carotenoids to improve hypertension
Published in Heliyon (01-09-2023)“…Hypertension is one of the major risk factors for cardiovascular diseases and the main reason for premature death in older adults. Although antihypertensive…”
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TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review
Published in Iranian journal of basic medical sciences (01-01-2024)“…Ischemic disorders, including myocardial infarction, cerebral ischemia, and peripheral vascular impairment, are the main common reasons for debilitating…”
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The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors
Published in Mediators of inflammation (2021)“…Inflammasome activation is a pivotal step for the maturation of IL-1β, which is involved in the development and progression of gastric cancer (GC)…”
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The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentylenetetrazol-induced kindled seizures and anxiety in rats
Published in BMC neuroscience (13-08-2018)“…Current antiepileptic drugs are not able to prevent recurrent seizures in all patients. Orexins are excitatory hypothalamic neuropeptides that their receptors…”
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Paraquat-induced systemic inflammation and increased oxidative markers in rats improved by Zataria multiflora extract and carvacrol
Published in Avicenna journal of phytomedicine (01-09-2020)“…Paraquat (PQ) is a herbicide which induces oxidative stress and inflammation. Anti-inflammatory and anti-oxidant effects were shown for (Z ) and carvacrol…”
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Inhibition of Interleukin-1 in the Treatment of Selected Cardiovascular Complications
Published in Current reviews in clinical and experimental pharmacology (01-01-2021)“…Interleukin-1 (IL-1) is a pro-inflammatory cytokine that is produced by endothelial cells, smooth muscle cells, and macrophages. It is an important regulator…”
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Iranian Journal of Basic Medical Sciences: Pursuing the COPE membership
Published in Iranian journal of basic medical sciences (01-01-2023)“…According to Elsevier, Committee on Publication Ethics (COPE) is “a forum for editors of peer-reviewed journals to discuss issues related to the integrity of…”
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Efficacy of orally administered montmorillonite in myoglobinuric acute renal failure model in male rats
Published in Iranian journal of basic medical sciences (01-01-2023)“…Acute kidney injury can be associated with serious consequences and therefore early treatment is critical to decreasing mortality and morbidity rate. We…”
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Commentary: Comment on the Effect of Endocannabinoid System on Rat Behavior
Published in Basic and clinical neuroscience (01-01-2017)“…I read the recently published article in Vol 6 (3) of Basic and Clinical Neuroscience entitled “Study the Effect of Endocannabinoid System on Rat Behavior in…”
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Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure
Published in Iranian journal of basic medical sciences (01-03-2019)“…Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, has significant neuroprotective effects and has been reported to…”
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