Search Results - "Rood, Julia E."
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Muscularis macrophage development in the absence of an enteric nervous system
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2018)“…The nervous system of the bowel regulates the inflammatory phenotype of tissue resident muscularis macrophages (MM), and in adult mice, enteric neurons are the…”
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Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy
Published in Journal of Virology (15-11-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis
Published in Frontiers in immunology (20-11-2018)“…Danger signals mediated through ST2, the interleukin-33 (IL-33) receptor, amplify CD8 T cell-mediated inflammation in the murine model of familial…”
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4
Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques
Published in PLoS pathogens (01-02-2013)“…Although the study of non-human primates has resulted in important advances for understanding HIV-specific immunity, a clear correlate of immune control over…”
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Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles
Published in PLoS pathogens (01-02-2011)“…If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over…”
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Inherited Autoinflammatory Syndromes
Published in Annual review of pathology (24-01-2022)“…Autoinflammation describes a collection of diverse diseases caused by indiscriminate activation of the immune system in an antigen-independent manner. The…”
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Genetic Deficiency of Interferon‐γ Reveals Interferon‐γ–Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2020)“…Objective Familial hemophagocytic lymphohistiocytosis (FHLH) is a complex cytokine storm syndrome caused by genetic abnormalities rendering CD8+ T cells and…”
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Improvement of Refractory Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease with Single-Agent Blockade of IL-1β and IL-18
Published in Journal of clinical immunology (01-01-2023)“…Systemic juvenile idiopathic arthritis associated with interstitial lung disease (SJIA-LD) represents a highly morbid subset of SJIA for which effective…”
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ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice
Published in Blood (28-01-2016)“…Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation…”
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Lytic Granule Loading of CD8 + T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control
Published in Immunity (Cambridge, Mass.) (19-12-2008)“…Virus-specific CD8 + T cells probably mediate control over HIV replication in rare individuals, termed long-term nonprogressors (LTNPs) or elite controllers…”
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Abnormal Eye Movements and Poor Feeding in an Infant
Published in Clinical pediatrics (01-05-2020)Get full text
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IL‐10 distinguishes a unique population of activated, effector‐like CD8+ T cells in murine acute liver inflammation
Published in Journal of leukocyte biology (01-04-2017)“…Systemic inflammation induces innate activation of effector‐like CD8+ T cells to infiltrate the liver and produce IL‐10. Immune‐mediated liver injury is a…”
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The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens
Published in The journal of applied laboratory medicine (01-03-2020)“…Irradiative sterilization of clinical specimens prior to chemical laboratory testing provides a way to not only sterilize pathogens and ensure laboratorian…”
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Genetic deficiency of IFNγ reveals IFNγ-independent manifestations of murine Hemophagocytic Lymphohistiocytosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (15-12-2019)Get full text
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The role of antigen-independent signals in CD8+ T cell responses in hemophagocytic syndromes
Published 01-01-2016“…Hemophagocytic syndromes represent extreme cases of uncontrolled immune activation resulting in severe disease. Dysregulated CD8+ T cell responses are…”
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