Search Results - "Rood, Julia E."

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    Muscularis macrophage development in the absence of an enteric nervous system by Avetisyan, Marina, Rood, Julia E., Lopez, Silvia Huerta, Sengupta, Rajarshi, Wright-Jin, Elizabeth, Dougherty, Joseph D., Behrens, Edward M., Heuckeroth, Robert O.

    “…The nervous system of the bowel regulates the inflammatory phenotype of tissue resident muscularis macrophages (MM), and in adult mice, enteric neurons are the…”
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    Journal Article
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    Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis by Rood, Julia E, Burn, Thomas N, Neal, Vanessa, Chu, Niansheng, Behrens, Edward M

    Published in Frontiers in immunology (20-11-2018)
    “…Danger signals mediated through ST2, the interleukin-33 (IL-33) receptor, amplify CD8 T cell-mediated inflammation in the murine model of familial…”
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    Journal Article
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    Inherited Autoinflammatory Syndromes by Rood, Julia E, Behrens, Edward M

    Published in Annual review of pathology (24-01-2022)
    “…Autoinflammation describes a collection of diverse diseases caused by indiscriminate activation of the immune system in an antigen-independent manner. The…”
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    Journal Article
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    Genetic Deficiency of Interferon‐γ Reveals Interferon‐γ–Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis by Burn, Thomas N., Weaver, Lehn, Rood, Julia E., Chu, Niansheng, Bodansky, Aaron, Kreiger, Portia A., Behrens, Edward M.

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2020)
    “…Objective Familial hemophagocytic lymphohistiocytosis (FHLH) is a complex cytokine storm syndrome caused by genetic abnormalities rendering CD8+ T cells and…”
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    Journal Article
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    Improvement of Refractory Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease with Single-Agent Blockade of IL-1β and IL-18 by Rood, Julia E., Rezk, Ayman, Pogoriler, Jennifer, Finn, Laura S., Burnham, Jon M., Josephson, Maureen B., Bar-Or, Amit, Behrens, Edward M., Canna, Scott W.

    Published in Journal of clinical immunology (01-01-2023)
    “…Systemic juvenile idiopathic arthritis associated with interstitial lung disease (SJIA-LD) represents a highly morbid subset of SJIA for which effective…”
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    Journal Article
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    ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice by Rood, Julia E., Rao, Sheila, Paessler, Michele, Kreiger, Portia A., Chu, Niansheng, Stelekati, Erietta, Wherry, E. John, Behrens, Edward M.

    Published in Blood (28-01-2016)
    “…Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation…”
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    Journal Article
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    IL‐10 distinguishes a unique population of activated, effector‐like CD8+ T cells in murine acute liver inflammation by Rood, Julia E., Canna, Scott W., Weaver, Lehn K., Tobias, John W., Behrens, Edward M.

    Published in Journal of leukocyte biology (01-04-2017)
    “…Systemic inflammation induces innate activation of effector‐like CD8+ T cells to infiltrate the liver and produce IL‐10. Immune‐mediated liver injury is a…”
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    Journal Article
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    The role of antigen-independent signals in CD8+ T cell responses in hemophagocytic syndromes by Rood, Julia E

    Published 01-01-2016
    “…Hemophagocytic syndromes represent extreme cases of uncontrolled immune activation resulting in severe disease. Dysregulated CD8+ T cell responses are…”
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    Dissertation