Search Results - "Rood, Julia"

Inherited Autoinflammatory Syndromes by Rood, Julia E, Behrens, Edward M

“…Autoinflammation describes a collection of diverse diseases caused by indiscriminate activation of the immune system in an antigen-independent manner. The…”
Get full text

Muscularis macrophage development in the absence of an enteric nervous system by Avetisyan, Marina, Rood, Julia E., Lopez, Silvia Huerta, Sengupta, Rajarshi, Wright-Jin, Elizabeth, Dougherty, Joseph D., Behrens, Edward M., Heuckeroth, Robert O.

“…The nervous system of the bowel regulates the inflammatory phenotype of tissue resident muscularis macrophages (MM), and in adult mice, enteric neurons are the…”
Get full text

Genetic Deficiency of Interferon‐γ Reveals Interferon‐γ–Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis by Burn, Thomas N., Weaver, Lehn, Rood, Julia E., Chu, Niansheng, Bodansky, Aaron, Kreiger, Portia A., Behrens, Edward M.

“…Objective Familial hemophagocytic lymphohistiocytosis (FHLH) is a complex cytokine storm syndrome caused by genetic abnormalities rendering CD8+ T cells and…”
Get full text

Improvement of Refractory Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease with Single-Agent Blockade of IL-1β and IL-18 by Rood, Julia E., Rezk, Ayman, Pogoriler, Jennifer, Finn, Laura S., Burnham, Jon M., Josephson, Maureen B., Bar-Or, Amit, Behrens, Edward M., Canna, Scott W.

“…Systemic juvenile idiopathic arthritis associated with interstitial lung disease (SJIA-LD) represents a highly morbid subset of SJIA for which effective…”
Get full text

ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice by Rood, Julia E., Rao, Sheila, Paessler, Michele, Kreiger, Portia A., Chu, Niansheng, Stelekati, Erietta, Wherry, E. John, Behrens, Edward M.

“…Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation…”
Get full text

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy by Migueles, Stephen A, Weeks, Kristin A, Nou, Eric, Berkley, Amy M, Rood, Julia E, Osborne, Christine M, Hallahan, Claire W, Cogliano-Shutta, Nancy A, Metcalf, Julia A, McLaughlin, Mary, Kwan, Richard, Mican, JoAnn M, Davey, Jr, Richard T, Connors, Mark

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Lytic Granule Loading of CD8 + T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control by Migueles, Stephen A., Osborne, Christine M., Royce, Cassandra, Compton, Alex A., Joshi, Rohan P., Weeks, Kristin A., Rood, Julia E., Berkley, Amy M., Sacha, Jonah B., Cogliano-Shutta, Nancy A., Lloyd, Margaret, Roby, Gregg, Kwan, Richard, McLaughlin, Mary, Stallings, Sara, Rehm, Catherine, O'Shea, Marie A., Mican, JoAnn, Packard, Beverly Z., Komoriya, Akira, Palmer, Sarah, Wiegand, Ann P., Maldarelli, Frank, Coffin, John M., Mellors, John W., Hallahan, Claire W., Follman, Dean A., Connors, Mark

“…Virus-specific CD8 + T cells probably mediate control over HIV replication in rare individuals, termed long-term nonprogressors (LTNPs) or elite controllers…”
Get full text

Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis by Rood, Julia E, Burn, Thomas N, Neal, Vanessa, Chu, Niansheng, Behrens, Edward M

“…Danger signals mediated through ST2, the interleukin-33 (IL-33) receptor, amplify CD8 T cell-mediated inflammation in the murine model of familial…”
Get full text

Abnormal Eye Movements and Poor Feeding in an Infant by Flynn, Rachel S., Hill, Morgan E., Rood, Julia E., Parga, Joanna J.

Get full text

IL‐10 distinguishes a unique population of activated, effector‐like CD8+ T cells in murine acute liver inflammation by Rood, Julia E., Canna, Scott W., Weaver, Lehn K., Tobias, John W., Behrens, Edward M.

“…Systemic inflammation induces innate activation of effector‐like CD8+ T cells to infiltrate the liver and produce IL‐10. Immune‐mediated liver injury is a…”
Get full text

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells by Patamawenu, Andy A, Wright, Nathaniel E, Shofner, Tulley, Evans, Sean, Manion, Maura M, Doria-Rose, Nicole, Migueles, Stephen A, Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A, Liang, C Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Jr, Julian, Lifson, Jeffrey, Connors, Mark

“…Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus,…”
Get full text

Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles by Migueles, Stephen A, Rood, Julia E, Berkley, Amy M, Guo, Tiffany, Mendoza, Daniel, Patamawenu, Andy, Hallahan, Claire W, Cogliano, Nancy A, Frahm, Nicole, Duerr, Ann, McElrath, M Juliana, Connors, Mark

“…If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over…”
Get full text

Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques by Mendoza, Daniel, Migueles, Stephen A, Rood, Julia E, Peterson, Bennett, Johnson, Sarah, Doria-Rose, Nicole, Schneider, Douglas, Rakasz, Eva, Trivett, Matthew T, Trubey, Charles M, Coalter, Vicky, Hallahan, Claire W, Watkins, David, Franchini, Genoveffa, Lifson, Jeffrey D, Connors, Mark

“…Although the study of non-human primates has resulted in important advances for understanding HIV-specific immunity, a clear correlate of immune control over…”
Get full text

The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens by Isenberg, Samantha L, Carter, Melissa D, Moon, Jonathan L, Laughlin, Sarah, Petway, Marla, Mojica, Mike A, Rood, Julia E, Gursky, Alexis K, Sheppard, Cody I, Bagarozzi, Dennis A, Pirkle, James L, Johnson, Rudolph C

“…Irradiative sterilization of clinical specimens prior to chemical laboratory testing provides a way to not only sterilize pathogens and ensure laboratorian…”
Get full text

601: SERUM GRANZYME B IS A SENSITIVE MARKER FOR FAMILIAL HLH TYPE 2 AND CORRELATES WITH DISEASE SEVERITY by Taylor, Matthew, Rood, Julia, Behrens, Edward

Get full text

Genetic deficiency of IFNγ reveals IFNγ-independent manifestations of murine Hemophagocytic Lymphohistiocytosis by Burn, Thomas N, Weaver, Lehn, Rood, Julia E, Chu, Niansheng, Bodansky, Aaron, Kreiger, Portia A, Behrens, Edward M

Get full text

Murine hemophagocytic lymphohistiocytosis can occur in the absence of interferon-gamma by Burn, Thomas Niels, Rood, Julia Elizabeth, Weaver, Lehn, Kreiger, Portia A, Behrens, Edward M

“…Abstract Hemophagocytic lymphohistiocytosis (HLH) is an ultimately fatal disease manifesting as a result of a dysregulated systemic hyperinflammatory response…”
Get full text

Interleukin-33 is a mediator of murine familial hemophagocytic lymphohistiocytosis (IRC5P.629) by Rood, Julia, Chu, Niansheng, Kreiger, Portia, Rao, Sheila, Stelekati, Erietta, Wherry, E., Behrens, Edward

“…Abstract Familial hemophagocytic lymphohistiocytosis (FHL) is a life-threatening disorder caused by uncontrolled, systemic immune activation. The murine model,…”
Get full text

Toll-like receptor 7-adapter complex modulates interferon-[alpha] production in HIV-stimulated plasmacytoid dendritic cells by Patamawenu, Andy A, Wright, Nathaniel E, Shofner, Tulley, Evans, Sean, Manion, Maura M, Doria-Rose, Nicole, Migueles, Stephen A, Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A, Liang, C. Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Julian, Lifson, Jeffrey, Connors, Mark, Apetrei, Cristian

“…Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-[alpha]) are believed to play an important role in human immunodeficiency…”
Get full text

The role of antigen-independent signals in CD8+ T cell responses in hemophagocytic syndromes by Rood, Julia E

“…Hemophagocytic syndromes represent extreme cases of uncontrolled immune activation resulting in severe disease. Dysregulated CD8+ T cell responses are…”
Get full text