Search Results - "Rongsheng Ma"

Backmapping from Multiresolution Coarse-Grained Models to Atomic Structures of Large Biomolecules by Restrained Molecular Dynamics Simulations Using Bayesian Inference by Peng, Junhui, Yuan, Chuang, Ma, Rongsheng, Zhang, Zhiyong

“…Coarse-grained (CG) simulations have allowed access to larger length scales and longer time scales in the study of the dynamic processes of large biomolecules…”
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The ∗-Ricci Operator on Hopf Real Hypersurfaces in the Complex Quadric by Ma, Rongsheng, Pei, Donghe

“…We study the ∗-Ricci operator on Hopf real hypersurfaces in the complex quadric. We prove that for Hopf real hypersurfaces in the complex quadric, the ∗-Ricci…”
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Ricci tensor on (κ,μ)-contact manifolds by Rongsheng Ma, Donghe Pei

“…We introduce the notion of semi-symmetric ∗-Ricci tensor and illustrate that a non-Sasakian (κ,μ)-contact manifold is ∗-Ricci semi-symmetric or has parallel…”
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Process of Fragment-Based Lead Discovery-A Perspective from NMR by Ma, Rongsheng, Wang, Pengchao, Wu, Jihui, Ruan, Ke

“…Fragment-based lead discovery (FBLD) has proven fruitful during the past two decades for a variety of targets, even challenging protein-protein interaction…”
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Some Curvature Properties on Lorentzian Generalized Sasakian-Space-Forms by Ma, Rongsheng, Pei, Donghe

“…In this paper, we investigate the Lorentzian generalized Sasakian-space-form. We give the necessary and sufficient conditions for the Lorentzian generalized…”
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Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit by Liu, Jiuyang, Zhang, Shuya, Liu, Mingqing, Liu, Yaqian, Nshogoza, Gilbert, Gao, Jia, Ma, Rongsheng, Yang, Yang, Wu, Jihui, Zhang, Jiahai, Li, Fudong, Ruan, Ke

“…As a reader of di‐methylated arginine on various proteins, such as histone, RNA polymerase II, PIWI and Fragile X mental retardation protein, the Tudor domain…”
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Fluorine Pseudocontact Shifts Used for Characterizing the Protein–Ligand Interaction Mode in the Limit of NMR Intermediate Exchange by Gao, Jia, Liang, E, Ma, Rongsheng, Li, Fudong, Liu, Yixiang, Liu, Jiuyang, Jiang, Ling, Li, Conggang, Dai, Haiming, Wu, Jihui, Su, Xuncheng, He, Wei, Ruan, Ke

“…The characterization of protein–ligand interaction modes becomes recalcitrant in the NMR intermediate exchange regime as the interface resonances are broadened…”
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Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex by Gao, Jia, Ma, Rongsheng, Wang, Wei, Wang, Na, Sasaki, Ryan, Snyderman, David, Wu, Jihui, Ruan, Ke

“…The small GTPase cycles between the inactive GDP form and the activated GTP form, catalyzed by the upstream guanine exchange factors. The modulation of such…”
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NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43 by Nshogoza, Gilbert, Liu, Yaqian, Gao, Jia, Liu, Mingqing, Moududee, Sayed Ala, Ma, Rongsheng, Li, Fudong, Zhang, Jiahai, Wu, Jihui, Shi, Yunyu, Ruan, Ke

“…The TDP-43 is originally a nuclear protein but translocates to the cytoplasm in the pathological condition. TDP-43, as an RNA-binding protein, consists of two…”
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Recent progress in fragment-based drug discovery facilitated by NMR spectroscopy by Wang, Lei, Gao, Jia, Ma, Rongsheng, Liu, Yaqian, Liu, Mingqing, Zhong, Fumei, Hu, Jie, Li, Shuju, Wu, Jihui, Jiang, Hualiang, Zhang, Jiahai, Ruan, Ke

“…Considerable developments have been observed in fragment-based lead/drug discovery (FBLD/FBDD) recently, with four drugs approved and many others under…”
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Natural gas storage in hydrates with the presence of promoters by Sun, Zhi-gao, Wang, Ruzhu, Ma, Rongsheng, Guo, Kaihua, Fan, Shuanshi

“…Hydrate technology is being developed for the storage and transport of natural gas. Micellar surfectant solutions were found to increase the gas hydrate…”
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Effect of surfactants and liquid hydrocarbons on gas hydrate formation rate and storage capacity by Sun, Zhigao, Wang, Ruzhu, Ma, Rongsheng, Guo, Kaihua, Fan, Shuanshi

“…Hydrate formation rate plays an important role in making hydrates for the storage and transport of natural gas. Micellar surfactant solutions were found to…”
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ast $-Ricci tensor on $ (\kappa, \mu) $-contact manifolds by Ma, Rongsheng, Pei, Donghe

“…We introduce the notion of semi-symmetric $ \ast $-Ricci tensor and illustrate that a non-Sasakian $ (\kappa, \mu) $-contact manifold is $ \ast $-Ricci…”
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Electrostatic interactions determine entrance/release order of substrates in the catalytic cycle of adenylate kinase by Ye, Chun, Ding, Chengtao, Ma, Rongsheng, Wang, Junfeng, Zhang, Zhiyong

“…Adenylate kinase is a monomeric phosphotransferase with important biological function in regulating concentration of adenosine triphosphate (ATP) in cells, by…”
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Repurposing Low-Molecular-Weight Drugs against the Main Protease of Severe Acute Respiratory Syndrome Coronavirus 2 by Gao, Jia, Zhang, Liang, Liu, Xiaodan, Li, Fudong, Ma, Rongsheng, Zhu, Zhongliang, Zhang, Jiahai, Wu, Jihui, Shi, Yunyu, Pan, Yueyin, Ge, Yushu, Ruan, Ke

“…The coronavirus disease pandemic caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected the global healthcare…”
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Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease by Zheng, Zhen, Zhang, Meilan, Wang, Yongheng, Ma, Rongsheng, Guo, Chenyun, Feng, Liubin, Wu, Jihui, Yao, Hongwei, Lin, Donghai

“…Prion diseases are caused by the propagation of misfolded cellular prion proteins (PrPs). A completely prion disease-resistant genotype, V127M129, has been…”
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Spindlin‐1 recognizes methylations of K20 and R23 of histone H4 tail by Wang, Chengliang, Zhan, Li, Wu, Minhao, Ma, Rongsheng, Yao, Jun, Xiong, Ying, Pan, Yang, Guan, Shenheng, Zhang, Xuan, Zang, Jianye

“…Using methods combining cross‐linking, pull‐down assays, and stable isotope labeling by amino acids in cell culture with mass spectrometry, we identified that…”
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NMR characterization of weak interactions between RhoGDI2 and fragment screening hits by Liu, Jiuyang, Gao, Jia, Li, Fudong, Ma, Rongsheng, Wei, Qingtao, Wang, Aidong, Wu, Jihui, Ruan, Ke

“…The delineation of intrinsically weak interactions between novel targets and fragment screening hits has long limited the pace of hit-to-lead evolution. Rho…”
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Proteins of well-defined structures can be designed without backbone readjustment by a statistical model by Zhou, Xiaoqun, Xiong, Peng, Wang, Meng, Ma, Rongsheng, Zhang, Jiahai, Chen, Quan, Liu, Haiyan

“…We report that using mainly a statistical energy model, protein sequence design for designable backbones can be carried out with high confidence without…”
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The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water‐mediated interaction network by Liu, Jiuyang, Li, Fudong, Bao, Hongyu, Jiang, Yiyang, Zhang, Shuya, Ma, Rongsheng, Gao, Jia, Wu, Jihui, Ruan, Ke

“…Tripartite motif‐containing protein 24 (TRIM24) is closely correlated with multiple cancers, and a recent study demonstrated that the bromodomain of TRIM24 is…”
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