Search Results - "Roncal, Norma E"

Assessment and Continued Validation of the Malaria SYBR Green I-Based Fluorescence Assay for Use in Malaria Drug Screening by JOHNSON, Jacob D, DENNULL, Richard A, GERENA, Lucia, LOPEZ-SANCHEZ, Miriam, RONCAL, Norma E, WATERS, Norman C

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Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery by Devine, William, Woodring, Jennifer L., Swaminathan, Uma, Amata, Emanuele, Patel, Gautam, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Pollastri, Michael P.

“…Tropical protozoal infections are a significant cause of morbidity and mortality worldwide; four in particular (human African trypanosomiasis (HAT), Chagas…”
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Kinase Scaffold Repurposing for Neglected Disease Drug Discovery: Discovery of an Efficacious, Lapatanib-Derived Lead Compound for Trypanosomiasis by Patel, Gautam, Karver, Caitlin E, Behera, Ranjan, Guyett, Paul J, Sullenberger, Catherine, Edwards, Peter, Roncal, Norma E, Mensa-Wilmot, Kojo, Pollastri, Michael P

“…Human African trypanosomiasis (HAT) is a neglected tropical disease caused by the protozoan parasite Trypanosoma brucei. Because drugs in use against HAT are…”
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Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors by Singh, Baljinder, Bernatchez, Jean A, McCall, Laura-Isobel, Calvet, Claudia M, Ackermann, Jasmin, Souza, Julia M, Thomas, Diane, Silva, Everton M, Bachovchin, Kelly A, Klug, Dana M, Jalani, Hitesh B, Bag, Seema, Buskes, Melissa J, Leed, Susan E, Roncal, Norma E, Penn, Erica C, Erath, Jessey, Rodriguez, Ana, Sciotti, Richard J, Campbell, Robert F, McKerrow, James, Siqueira-Neto, Jair L, Ferrins, Lori, Pollastri, Michael P

“…Utilizing a target repurposing and parasite-hopping approach, we tested a previously reported library of compounds that were active against Trypanosoma brucei,…”
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Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing? by Amata, Emanuele, Xi, Hualin, Colmenarejo, Gonzalo, Gonzalez-Diaz, Rosario, Cordon-Obras, Carlos, Berlanga, Manuela, Manzano, Pilar, Erath, Jessey, Roncal, Norma E, Lee, Patricia J, Leed, Susan E, Rodriguez, Ana, Sciotti, Richard J, Navarro, Miguel, Pollastri, Michael P

“…A kinase-targeting cell-based high-throughput screen (HTS) against Trypanosoma brucei was recently reported, and this screening set included the Published…”
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Targeting the Fatty Acid Biosynthesis Enzyme, β-Ketoacyl−Acyl Carrier Protein Synthase III (PfKASIII), in the Identification of Novel Antimalarial Agents by Lee, Patricia J, Bhonsle, Jayendra B, Gaona, Heather W, Huddler, Donald P, Heady, Tiffany N, Kreishman-Deitrick, Mara, Bhattacharjee, Apurba, McCalmont, William F, Gerena, Lucia, Lopez-Sanchez, Miriam, Roncal, Norma E, Hudson, Thomas H, Johnson, Jacob D, Prigge, Sean T, Waters, Norman C

“…The importance of fatty acids to the human malaria parasite, Plasmodium falciparum, and differences due to a type I fatty acid synthesis (FAS) pathway in the…”
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Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis by Patel, Gautam, Karver, Caitlin E, Behera, Ranjan, Guyett, Paul J, Sullenberger, Catherine, Edwards, Peter, Roncal, Norma E, Mensa-Wilmot, Kojo, Pollastri, Michael P

“…Human African trypanosomiasis (HAT) is a neglected tropical disease caused by the protozoan parasite Trypanosoma brucei . Because drugs in use against HAT are…”
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