Search Results - "Roncador, G"

Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer by CARRETERO, J, MEDINA, P. P, SANCHEZ-CESPEDES, M, BLANCO, R, SMIT, L, TANG, M, RONCADOR, G, MAESTRE, L, CONDE, E, LOPEZ-RIOS, F, CLEVERS, H. C

“…LKB1, mutated in Peutz-Jeghers and in sporadic lung tumours, phosphorylates a group of protein kinases named AMP-activated protein kinase (AMPK)-related…”
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Identification of MNDA as a new marker for nodal marginal zone lymphoma by Kanellis, G, Roncador, G, Arribas, A, Mollejo, M, Montes-Moreno, S, Maestre, L, Campos-Martin, Y, Ríos Gonzalez, J L, Martinez-Torrecuadrada, J L, Sanchez-Verde, L, Pajares, R, Cigudosa, J C, Martin, M C, Piris, M A

“…Clinical and biological studies on nodal marginal zone lymphoma (NMZL) are hampered by the lack of specific diagnostic markers and the low reproducibility of…”
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Expression of clec9a in the oral cancer microenvironment. A preliminary immunohistochemical pilot study by Peña-Cardelles, J-F, Pozo-Kreilinger, J-J, Roncador, G, Esteban-Hernández, J, Cebrián-Carretero, J-L, Moro-Rodríguez, J-E

“…The search for treatments to improve cancer survival has led to the emergence of immunotherapy and the study of the tumour microenvironment existing in…”
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FOXP3, a selective marker for a subset of adult T-cell leukaemia lymphoma by RONCADOR, G, GARCIA, J. F, GARCIA, J. F, MAESTRE, L, LUCAS, E, MENARGUEZ, J, OHSHIMA, K., NAKAMURA, S, BANHAM, A. H, PIRIS, M. A

“…FOXP3 is a forkhead transcription factor family member, implicated in T-cell regulation, activation and differentiation. FOXP3 has been shown to be a master…”
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Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene by Tavera-Tapia, A., Pérez-Cabornero, L., Macías, J. A., Ceballos, M. I., Roncador, G., de la Hoya, M., Barroso, A., Felipe-Ponce, V., Serrano-Blanch, R., Hinojo, C., Miramar-Gallart, M. D., Urioste, M., Caldés, T., Santillan-Garzón, S., Benitez, J., Osorio, A.

“…Purpose There is still a considerable percentage of hereditary breast and ovarian cancer (HBOC) cases not explained by BRCA1 and BRCA2 genes. In this report,…”
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p38α limits the contribution of MAP17 to cancer progression in breast tumors by Guijarro, M V, Vergel, M, Marin, J J, Muñoz-Galván, S, Ferrer, I, Cajal, S Ramon y, Roncador, G, Blanco-Aparicio, C, Carnero, A

“…MAP17 is a small, 17-kDa, non-glycosylated membrane protein that is overexpressed in a percentage of carcinomas. In the present work, we have analyzed the role…”
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Expression of programmed death-1 (CD279) in primary cutaneous B-cell lymphomas with correlation to lymphoma entities and biological behaviour by Mitteldorf, C., Bieri, M., Wey, N., Kerl, K., Kamarachev, J., Pfaltz, M., Kutzner, H., Roncador, G., Tomasini, D., Kempf, W.

“…Summary Background Programmed death‐1 (PD‐1/CD279) is a cell‐surface protein expressed in activated T cells and a subset of T lymphocytes including follicular…”
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Elevated receptor for activated C kinase 1 expression is involved in intracellular Ca2+ influx and potentially associated with compromised regulatory T cell function in patients with asthma by Negoro, T., Shimizu, S., Narushima, M., Banham, A. H., Wakabayashi, H., Takayanagi, R., Hagiwara, T., Roncador, G., Osabe, T., Yanai, T., Kin, M., Ikeda, K., Endo, A., Akiyama, H., Nakano, Y.

“…Summary Background Regulatory T cells (Tregs) are activated during anergy in response to T cell receptor (TCR) activation and functional immune suppression…”
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FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment by Raghavan, S, Cao, D, Widhe, M, Roth, K, Herrath, J, Engström, M, Roncador, G, Banham, A H, Trollmo, C, Catrina, A I, Malmström, V

“…To analyse the distribution of FOXP3+CD25+CD4+ regulatory T cells (Treg) in peripheral blood, synovial fluid and tissue of patients with rheumatic disease…”
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Differential expression of NF-κB pathway genes among peripheral T-cell lymphomas by MARTINEZ-DELGADO, B, CUADROS, M, HONRADO, E, RUIZ DE LA PARTE, A, RONCADOR, G, ALVES, J, CASTRILLO, J. M, RIVAS, C, BENITEZ, J

“…Nuclear factor kappa B (NF-κB) is one important pathway in T-cell proliferation and survival. In a previously reported microarrray study, we found NF-κB…”
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Paucity of FOXP3 cells in skin and peripheral blood distinguishes Sézary syndrome from other cutaneous T-cell lymphomas by KLEMKE, C.-D, FRITZSCHING, B, GOERDT, S, KRAMMER, P. H, SURI-PAYER, E, FRANZ, B, KLEINMANN, E. V, OBERLE, N, POENITZ, N, SYKORA, J, BANHAM, A. H, RONCADOR, G, KUHN, A

“…Cutaneous T-cell lymphomas (CTCL) are mainly comprised of two variants: mycosis fungoides (MF) with CD4(+) tumor cells confined to the skin and the leukemic…”
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Proliferation centers in chronic lymphocytic leukemia: the niche where NF-κB activation takes place by Herreros, B, Rodríguez-Pinilla, S M, Pajares, R, Martínez-Gónzalez, M Á, Ramos, R, Munoz, I, Montes-Moreno, S, Lozano, M, Sánchez-Verde, L, Roncador, G, Sánchez-Beato, M, de Otazu, R D, Pérez-Guillermo, M, Mestre, M J, Bellas, C, Piris, M Á

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The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells by Pulford, K, Banham, A H, Lyne, L, Jones, M, Ippolito, G C, Liu, H, Tucker, P W, Roncador, G, Lucas, E, Ashe, S, Stockwin, L, Walewska, R, Karran, L, Gascoyne, R D, Mason, D Y, Dyer, M J S

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Functional characterization of HLA‐F and binding of HLA‐F tetramers to ILT2 and ILT4 receptors by Lepin, Eric J. M., Bastin, Judy M., Allan, David S. J., Roncador, Giovanna, Braud, Veronique M., Mason, David Y., Merwe, P. Anton van der, McMichael, Andrew J., Bell, John I., Powis, Stephen H., O'Callaghan, Christopher A.

“…HLA‐F is a human non‐classical MHC molecule. Recombinant HLA‐F heavy chain was refolded with β2‐microglobulin to form a stable complex. This complex was used…”
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Expression pattern of XBP1(S) in human B-cell lymphomas by Maestre, Lorena, Tooze, Reuben, Canamero, Marta, Montes-Moreno, Santiago, Ramos, Rocio, Doody, Gina, Boll, May, Barrans, Sharon, Baena, Sara, Piris, Miguel Angel, Roncador, Giovanna

“…1 Monoclonal Antibodies Unit, Biotechnology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain; 2 Section of Experimental Haematology, Leeds…”
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PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy by COOPER, C. D. O, LIGGINS, A. P, AIT-TAHAR, K, RONCADOR, G, BANHAM, A. H, PULFORD, K

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Simultaneous detection of the immunophenotypic markers and genetic aberrations on routinely processed paraffin sections of lymphoma samples by means of the FICTION technique by MARTINEZ-RAMIREZ, A, CIGUDOSA, J. C, MAESTRE, L, RODRIGUEZ-PERALES, S, HARALAMBIEVA, E, BENITEZ, J, RONCADOR, G

“…Disciplines such as morphology, immunophenotyping and genetics widely contributed over decades to the understanding of the cellular mechanisms of cancer. To…”
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Frequent expression of the NPM-ALK chimeric fusion protein in anaplastic large-cell lymphoma, lympho-histiocytic type by Pileri, SA, Pulford, K, Mori, S, Mason, DY, Sabattini, E, Roncador, G, Piccioli, M, Ceccarelli, C, Piccaluga, PP, Santini, D, Leone, O, Stein, H, Falini, B

“…The revised European-American lymphoma classification recognizes a subtype of anaplastic large-cell lymphoma (ALCL), termed lympho-histiocytic because of its…”
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A Unifying Microenvironment Model in Follicular Lymphoma: Outcome Is Predicted by Programmed Death-1–Positive, Regulatory, Cytotoxic, and Helper T Cells and Macrophages by Wahlin, Björn Engelbrekt, Aggarwal, Mohit, Montes-Moreno, Santiago, Gonzalez, Luis Francisco, Roncador, Giovanna, Sanchez-Verde, Lidia, Christensson, Birger, Sander, Birgitta, Kimby, Eva

“…Purpose: The microenvironment influences outcome in follicular lymphoma. Our hypothesis was that several immune cell subsets are important for disease outcome…”
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Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single‐cell level by Roncador, Giovanna, Brown, Philip J., Maestre, Lorena, Hue, Sophie, Martínez‐Torrecuadrada, Jorge L., Ling, Khoon‐Lin, Pratap, Sarah, Toms, Christy, Fox, Bridget C., Cerundolo, Vincenzo, Powrie, Fiona, Banham, Alison H.

“…The transcription factor FOXP3 plays a key role in CD4+CD25+ regulatory T cell function and represents a specific marker for these cells. Despite its strong…”
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