Search Results - "Ronald F. Mervis"

Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms by Costa, David A, Cracchiolo, Jennifer R, Bachstetter, Adam D, Hughes, Tiffany F, Bales, Kelly R, Paul, Steven M, Mervis, Ronald F, Arendash, Gary W, Potter, Huntington

“…Abstract Lifelong cognitive stimulation is associated with a lower risk of Alzheimer's disease (AD), but causality is difficult to prove. We therefore sought…”
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Behavior, protein, and dendritic changes after model traumatic brain injury and treatment with nanocoffee particles by Ratliff, Whitney A, Saykally, Jessica N, Mervis, Ronald F, Lin, Xiaoyang, Cao, Chuanhai, Citron, Bruce A

“…Traumatic brain injury (TBI) is a widespread public health problem and a signature injury of our military in modern conflicts. Despite the long-term effects of…”
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Influence of predator stress on the consolidation versus retrieval of long-term spatial memory and hippocampal spinogenesis by Diamond, David M., Campbell, Adam M., Park, Collin R., Woodson, James C., Conrad, Cheryl D., Bachstetter, Adam D., Mervis, Ronald F.

“…We have studied the influence of predator stress (30 min of cat exposure) on long‐term (24 h) spatial memory and the density of spines in basilar dendrites of…”
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Ontogenetic Alterations in Molecular and Structural Correlates of Dendritic Growth after Developmental Exposure to Polychlorinated Biphenyls by Lein, Pamela J., Yang, Dongren, Adam D. Bachstetter, Tilson, Hugh A., Harry, G. Jean, Ronald F. Mervis, Prasada Rao S. Kodavanti

“…Objective: Perinatal exposure to polychlorinated biphenyls (PCBs) is associated with decreased IQ scores, impaired learning and memory, psychomotor…”
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Insulin-like growth factor 1 is essential for normal dendritic growth by Cheng, Clara M., Mervis, Ronald F., Niu, Shui-Lin, Salem Jr, Norman, Witters, Lee A., Tseng, Victor, Reinhardt, Rickey, Bondy, Carolyn A.

“…This study evaluated somatic and dendritic growth of neurons in the frontoparietal cortex of Igf1–/– brains. Pyramidal neuron density was increased by ∼25% (P…”
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Effect of mild blast-induced TBI on dendritic architecture of the cortex and hippocampus in the mouse by Ratliff, Whitney A., Mervis, Ronald F., Citron, Bruce A., Schwartz, Brian, Rubovitch, Vardit, Schreiber, Shaul, Pick, Chaim G.

“…Traumatic brain injury (TBI) has been designated as a signature injury of modern military conflicts. Blast trauma, in particular, has come to make up a…”
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Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory by Mervis, Ronald F, Sung, Amy, Brandon, Nicholas J, Arias, Robert, Kelley, Cody, Hirst, Warren D, Pangalos, Menelas N, Day, Mark, Navarra, Rachel, Marquis, Karen L, Revilla-Sanchez, Raquel, Grauer, Steve, Zhang, Guoming, Reinhart, Peter H, Bitran, Daniel, Liu, Feng, Moss, Stephen J, Muñiz, Luis C, Pulito, Virginia

“…Estrogens have long been implicated in influencing cognitive processes, yet the molecular mechanisms underlying these effects and the roles of the estrogen…”
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Hippocampal Abnormalities and Enhanced Excitability in a Murine Model of Human Lissencephaly by Fleck, Mark W, Hirotsune, Shinji, Gambello, Michael J, Phillips-Tansey, Emily, Suares, Gregory, Mervis, Ronald F, Wynshaw-Boris, Anthony, McBain, Chris J

“…Human cortical heterotopia and neuronal migration disorders result in epilepsy; however, the precise mechanisms remain elusive. Here we demonstrate severe…”
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SIRT1 is essential for normal cognitive function and synaptic plasticity by Michán, Shaday, Li, Ying, Chou, Maggie Meng-Hsiu, Parrella, Edoardo, Ge, Huanying, Long, Jeffrey M, Allard, Joanne S, Lewis, Kaitlyn, Miller, Marshall, Xu, Wei, Mervis, Ronald F, Chen, Jing, Guerin, Karen I, Smith, Lois E H, McBurney, Michael W, Sinclair, David A, Baudry, Michel, de Cabo, Rafael, Longo, Valter D

“…Conservation of normal cognitive functions relies on the proper performance of the nervous system at the cellular and molecular level. The mammalian…”
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Mild blast-related TBI in a mouse model alters amygdalar neurostructure and circuitry by Ratliff, Whitney A., Mervis, Ronald F., Citron, Bruce A., Schwartz, Brian, Rubovitch, Vardit, Schreiber, Shaul, Pick, Chaim G.

“…Traumatic brain injury (TBI) continues to be a signature injury of our modern conflicts. Due in part to increased use of improvised explosive devices (IEDs),…”
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Dendritic morphology of amygdala and hippocampal neurons in more and less predator stress responsive rats and more and less spontaneously anxious handled controls by Adamec, Robert, Hebert, Mark, Blundell, Jacqueline, Mervis, Ronald F.

“…► Golgi analysis of dendrites was applied to amygdala (BLA) and dorsal hippocampal (DHC) cells. ► More and less anxious (MA, LA) handled controls (HC) and…”
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Sidestream Smoke Affects Dendritic Complexity and Astrocytes After Model Mild Closed Head Traumatic Brain Injury by Ratliff, Whitney A., Saykally, Jessica N., Keeley, Kristen L., Driscoll, David C., Murray, Kathleen E., Okuka, Maja, Mervis, Ronald F., Delic, Vedad, Citron, Bruce A.

“…Mild traumatic brain injuries can have long-term consequences that interfere with the life of the patient and impose a burden on our health care system…”
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Repetitive Mild Closed Head Injury Alters Protein Expression and Dendritic Complexity in a Mouse Model by Saykally, Jessica N, Ratliff, Whitney A, Keeley, Kristen L, Pick, Chaim G, Mervis, Ronald F, Citron, Bruce A

“…Worldwide head injuries are a growing problem. In the United States alone, 1.7 million people suffer a head injury each year. While most of these injuries are…”
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Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy by Cantero, Gloria, Liu, Xiao-Bo, Mervis, Ronald F, Lazaro, Maria T, Cederbaum, Stephen D, Golshani, Peyman, Lipshutz, Gerald S

“…Arginase 1 deficiency is a urea cycle disorder associated with hyperargininemia, spastic diplegia, loss of ambulation, intellectual disability, and seizures…”
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The dendrites of granule cell layer neurons are the primary injury sites in the “Brain Diabetes” rat by Shingo, Akiko Sheala, Mervis, Ronald F., Kanabayashi, Tomomichi, Kito, Shozo, Murase, Toshio

“…We previously demonstrated that rats that receive dorsal third ventricle (3V) streptozotocin (STZ) injections (STZ-3V-rats) exhibit cognitive decline as…”
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Developmental Exposure to Polychlorinated Biphenyls Interferes with Experience-Dependent Dendritic Plasticity and Ryanodine Receptor Expression in Weanling Rats by Yang, Dongren, Kim, Kyung Ho, Phimister, Andrew, Bachstetter, Adam D., Ward, Thomas R., Stackman, Robert W., Mervis, Ronald F., Wisniewski, Amy B., Klein, Sabra L., Kodavanti, Prasada Rao S., Anderson, Kim A., Wayman, Gary, Pessah, Isaac N., Lein, Pamela J.

“…Background: Neurodevelopmental disorders are associated with altered patterns of neuronal connectivity. A critical determinant of neuronal connectivity is the…”
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Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory by Malone, John I, Hanna, Suzan, Saporta, Samuel, Mervis, Ronald F, Park, Collin R, Chong, Ling, Diamond, David M

“…Background/Objective:  We previously reported that chronic hyperglycemia, but not hypoglycemia, was associated with the reduction of neuronal size in the rat…”
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Four weeks lithium treatment alters neuronal dendrites in the rat hippocampus by Shim, Seong S., Hammonds, Michael D., Mervis, Ronald F.

“…A large body of evidence from molecular, cellular and human studies suggests that lithium may enhance synaptic plasticity, which may be associated with its…”
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Cardiac arrest with cardiopulmonary resuscitation reduces dendritic spine density in CA1 pyramidal cells and selectively alters acquisition of spatial memory by Neigh, Gretchen N., Glasper, Erica R., Kofler, Julia, Traystman, Richard J., Mervis, Ronald F., Bachstetter, Adam, DeVries, A. Courtney

“…The hippocampus is highly sensitive to ischemia and is one of the most extensively damaged regions of brain during cardiac arrest. Damage to hippocampus can…”
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Chronic Methamphetamine Induces Structural Changes in Frontal Cortex Neurons and Upregulates Type I Interferons by Coutinho, Alice, Flynn, Claudia, Burdo, Tricia H., Mervis, Ronald F., Fox, Howard S.

“…While methamphetamine-induced changes in brain neurotransmitters, their receptors, and transporters are well studied, the means by which methamphetamine abuse…”
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