Search Results - "Ronai, Z A"

Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy by Lau, E, Sedy, J, Sander, C, Shaw, M A, Feng, Y, Scortegagna, M, Claps, G, Robinson, S, Cheng, P, Srivas, R, Soonthornvacharin, S, Ideker, T, Bosenberg, M, Gonzalez, R, Robinson, W, Chanda, S K, Ware, C, Dummer, R, Hoon, D, Kirkwood, J M, Ronai, Z A

“…The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms…”
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Metabolic rewiring in melanoma by Ratnikov, B I, Scott, D A, Osterman, A L, Smith, J W, Ronai, Z A

“…Oncogene-driven metabolic rewiring is an adaptation to low nutrient and oxygen conditions in the tumor microenvironment that enables cancer cells of diverse…”
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Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma by Scortegagna, M, Ruller, C, Feng, Y, Lazova, R, Kluger, H, Li, J-L, De, S K, Rickert, R, Pellecchia, M, Bosenberg, M, Ronai, Z A

“…Phosphoinositide-dependent kinase-1 (PDK1) is a serine/threonine protein kinase that phosphorylates members of the conserved AGC kinase superfamily, including…”
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RACK1 Function in Cell Motility and Protein Synthesis by Gandin, Valentina, Senft, Daniela, Topisirovic, Ivan, Ronai, Ze'ev A

“…The receptor for activated C kinase 1 (RACK1) serves as an adaptor for a number of proteins along the MAPK, protein kinase C, and Src signaling pathways. The…”
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Transcriptional repression of IFN beta 1 by ATF2 confers melanoma resistance to therapy by Lau, E, Sedy, J, Sander, C, Shaw, M A, Feng, Y, Scortegagna, M, Claps, G, Robinson, S, Cheng, P, Srivas, R, Soonthornvacharin, S, Ideker, T, Bosenberg, M, Gonzalez, R, Robinson, W, Chanda, S K, Ware, C, Dummer, R, Hoon, D, Kirkwood, J M, Ronai, Z A

“…The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms…”
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Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability by Kim, H, Claps, G, Möller, A, Bowtell, D, Lu, X, Ronai, Z A

“…Changes in cell adhesion and polarity are closely associated with epithelial cell transformation and metastatic capacity. The tumor suppressor protein ASPP…”
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Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of BrafV600E::Pten–/– melanoma by Scortegagna, M, Ruller, C, Feng, Y, Lazova, R, Kluger, H, Li, J-L, De, S K, Rickert, R, Pellecchia, M, Bosenberg, M, Ronai, Z A

“…Phosphoinositide-dependent kinase-1 (PDK1) is a serine/threonine protein kinase that phosphorylates members of the conserved AGC kinase superfamily, including…”
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Analysis of the effect of neuropeptides and cannabinoids in gastric mucosal defense initiated centrally in the rat by Shujaa, N, Zadori, Z S, Ronai, A Z, Barna, I, Mergl, Z, Mozes, M M, Gyires, K

“…Increasing number of evidence suggest that gastric mucosal protection can be induced also centrally. Several neuropeptides, such as TRH, amylin,…”
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Diprotin, an inhibitor of dipeptidyl aminopeptidase IV(EC 3.4.14.5) produces naloxone — reversible analgesia in rats by Rónai, András Z., Timár, Julianna, Makó, Éva, Erdóo, Franciska, Gyarmati, Zsuzsanna, Tóth, Géza, Orosz, György, Fürst, Susanne, Székely, József I.

“…The dipeptidyl aminopeptidase IV (DP IV) inhibitor Diprotin A produces a full, dose-dependent, short-lasting and naloxone-reversible analgesia in the rat…”
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Enhancement of major histocompatibility class I protein synthesis by DNA damage in cultured human fibroblasts and keratinocytes by LAMBERT, M. E, RONAI, Z. A, WEINSTEIN, I. B, GARRELS, J. I

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells by Ronai, Z A, Okin, E, Weinstein, I B

“…The exposure of a polyoma virus transformed rat fibroblast cell line H3 to UV-C irradiation (254 nm) causes a transient increase in the abundance of RNAs for…”
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Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication by Ronai, Z A, Weinstein, I B

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide by Ronai, Z A, Gradia, S, el-Bayoumy, K, Amin, S, Hecht, S S

“…Racemic anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide (anti-B[c]PhDE) is a powerful rat mammary carcinogen and is one of the most potent diol-epoxide…”
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Comparative mouse skin tumorigenicity and induction of Ha-ras mutations by bay region diol epoxides of 5-methylchrysene and 5,6-dimethylchrysene by HECHT, S. S, RONAI, Z. A, DOLAN, L, DESAI, D, AMIN, S

“…We compared the tumor-initiating activities toward mouse skin of two structurally related polycyclic aromatic hydrocarbon diol epoxides: racemic…”
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Intracerebroventricular injection of clonidine releases β-endorphin to induce mucosal protection in the rat by Gyires, K, Rónai, A.Z, Müllner, K, Fürst, S

“…The possibility that the endogenous opioid system could be involved in the central nervous system (CNS)-mediated gastroprotective effect of clonidine was…”
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Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat by Gyires, K, Rónai, A Z

“…This study evaluated the contribution of supraspinal opioid receptors to gastric mucosal protection in the rat. Intracerebroventricular (i.c.v.) and…”
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Design of opioid peptides for a potential delta-receptor affinity label function: comparison with the mu-specific Tyr-D-Ala-Gly-(Me)Phe-chloromethyl ketone by Rónai, A Z, Hepp, J, Magyar, A, Borsodi, A, Medzihradszky, K

“…To find a delta-opioid receptor preferring peptide structure containing an Asp residue in a potentially interacting position, Tyr-Pro-Phe-Asp,…”
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Identification of an Intracellular Protein that Specifically Interacts with Photoaffinity-Labeled Oncogenic P21 Protein by Lee, Grace, Ronai, Zeev A., Pincus, Matthew R., Brandt-Rauf, Paul W., Murphy, Randall B., Delohery, Thomas M., Nishimura, Susumu, Yamaizumi, Ziro, Weinstein, I. Bernard

“…An oncogenic 21-kDa (p21) protein (Harvey RAS protein with Val-12) has been covalently modified with a functional reagent that contains a photoactivatable…”
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Effects of 8-methoxypsoralen and ultraviolet light A on EGF receptor (HER-1) expression by Yang, X Y, Ronai, Z A, Santella, R M, Weinstein, I B

“…Activation of psoralens by ultraviolet light irradiation at 308-400 nm (UVA) is used in the photochemical treatment of psoriasis. While the major effect of…”
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Fusarium moniliforme metabolites: genotoxicity of culture extracts by Lu, S J, Ronai, Z A, Li, M H, Jeffrey, A M

“…Fusarin C (FC) is a potent mutagen which has been isolated from Fusarium moniliforme culture extracts (FME). We have confirmed that the mutagenicity of these…”
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