Search Results - "Rommelaere, Samuel"

Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage by Li, Xiaoxue, Rommelaere, Samuel, Kondo, Shu, Lemaitre, Bruno

“…Animals require complex metabolic and physiological adaptations to maintain the function of vital organs in response to environmental stresses and infection…”
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Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps by Dostálová, Anna, Rommelaere, Samuel, Poidevin, Mickael, Lemaitre, Bruno

“…Members of the thioester-containing protein (TEP) family contribute to host defence in both insects and mammals. However, their role in the immune response of…”
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Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii by Masson, Florent, Rommelaere, Samuel, Marra, Alice, Schüpfer, Fanny, Lemaitre, Bruno

“…Insects are frequently infected with heritable bacterial endosymbionts. Endosymbionts have a dramatic impact on their host physiology and evolution. Their…”
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The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila by Rommelaere, Samuel, Boquete, Jean-Philippe, Piton, Jérémie, Kondo, Shu, Lemaitre, Bruno

“…In ectotherms, increased ambient temperature requires the organism to consume substantial amounts of energy to sustain a higher metabolic rate, prevent…”
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CERT1 mutations perturb human development by disrupting sphingolipid homeostasis by Gehin, Charlotte, Lone, Museer A, Lee, Winston, Capolupo, Laura, Ho, Sylvia, Adeyemi, Adekemi M, Gerkes, Erica H, Stegmann, Alexander Pa, López-Martín, Estrella, Bermejo-Sánchez, Eva, Martínez-Delgado, Beatriz, Zweier, Christiane, Kraus, Cornelia, Popp, Bernt, Strehlow, Vincent, Gräfe, Daniel, Knerr, Ina, Jones, Eppie R, Zamuner, Stefano, Abriata, Luciano A, Kunnathully, Vidya, Moeller, Brandon E, Vocat, Anthony, Rommelaere, Samuel, Bocquete, Jean-Philippe, Ruchti, Evelyne, Limoni, Greta, Van Campenhoudt, Marine, Bourgeat, Samuel, Henklein, Petra, Gilissen, Christian, van Bon, Bregje W, Pfundt, Rolph, Willemsen, Marjolein H, Schieving, Jolanda H, Leonardi, Emanuela, Soli, Fiorenza, Murgia, Alessandra, Guo, Hui, Zhang, Qiumeng, Xia, Kun, Fagerberg, Christina R, Beier, Christoph P, Larsen, Martin J, Valenzuela, Irene, Fernández-Álvarez, Paula, Xiong, Shiyi, Śmigiel, Robert, López-González, Vanesa, Armengol, Lluís, Morleo, Manuela, Selicorni, Angelo, Torella, Annalaura, Blyth, Moira, Cooper, Nicola S, Wilson, Valerie, Oegema, Renske, Herenger, Yvan, Garde, Aurore, Bruel, Ange-Line, Tran Mau-Them, Frederic, Maddocks, Alexis Br, Bain, Jennifer M, Bhat, Musadiq A, Costain, Gregory, Kannu, Peter, Marwaha, Ashish, Champaigne, Neena L, Friez, Michael J, Richardson, Ellen B, Gowda, Vykuntaraju K, Srinivasan, Varunvenkat M, Gupta, Yask, Lim, Tze Y, Sanna-Cherchi, Simone, Lemaitre, Bruno, Yamaji, Toshiyuki, Hanada, Kentaro, Burke, John E, Jakšić, Ana Marjia, McCabe, Brian D, De Los Rios, Paolo, Hornemann, Thorsten, D'Angelo, Giovanni, Gennarino, Vincenzo A

“…Neural differentiation, synaptic transmission, and action potential propagation depend on membrane sphingolipids, whose metabolism is tightly regulated…”
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PPARalpha regulates the production of serum Vanin-1 by liver by Rommelaere, Samuel, Millet, Virginie, Gensollen, Thomas, Bourges, Christophe, Eeckhoute, Jérôme, Hennuyer, Nathalie, Baugé, Eric, Chasson, Lionel, Cacciatore, Ivana, Staels, Bart, Pitari, Giuseppina, Galland, Franck, Naquet, Philippe

“…•The Vnn1 pantetheinase is expressed in liver and secreted in serum.•The vnn1 gene is a target of PPARα regulation.•The level of serum Vnn1 production reflects…”
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Sox17 regulates liver lipid metabolism and adaptation to fasting by Rommelaere, Samuel, Millet, Virginie, Vu Manh, Thien-Phong, Gensollen, Thomas, Andreoletti, Pierre, Cherkaoui-Malki, Mustapha, Bourges, Christophe, Escalière, Bertrand, Du, Xin, Xia, Yu, Imbert, Jean, Beutler, Bruce, Kanai, Yoshiakira, Malissen, Bernard, Malissen, Marie, Tailleux, Anne, Staels, Bart, Galland, Franck, Naquet, Philippe

“…Liver is a major regulator of lipid metabolism and adaptation to fasting, a process involving PPARalpha activation. We recently showed that the Vnn1 gene is a…”
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Disproportionate investment in Spiralin B production limits in-host growth and favors the vertical transmission of Spiroplasma insect endosymbionts by Masson, Florent, Rommelaere, Samuel, Schüpfer, Fanny, Boquete, Jean-Philippe, Lemaitre, Bruno

“…Insects frequently harbor endosymbionts, which are bacteria housed within host tissues. These associations are stably maintained over evolutionary timescales…”
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A humoral stress response protects Drosophila tissues from antimicrobial peptides by Rommelaere, Samuel, Carboni, Alexia, Bada Juarez, Juan F, Boquete, Jean-Philippe, Abriata, Luciano A, Teixeira Pinto Meireles, Fernando, Rukes, Verena, Vincent, Crystal, Kondo, Shu, Dionne, Marc S, Dal Peraro, Matteo, Cao, Chan, Lemaitre, Bruno

“…7An efficient immune system must provide protection against a broad range of pathogens without causing excessive collateral tissue damage. While immune…”
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A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila by Petrignani, Bianca, Rommelaere, Samuel, Hakim-Mishnaevski, Ketty, Masson, Florent, Ramond, Elodie, Hilu-Dadia, Reut, Poidevin, Mickael, Kondo, Shu, Kurant, Estee, Lemaitre, Bruno

“…Programmed cell death plays a fundamental role in development and tissue homeostasis. Professional and non-professional phagocytes achieve the proper…”
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Protein target highlights in CASP15: Analysis of models by structure providers by Alexander, Leila T., Durairaj, Janani, Kryshtafovych, Andriy, Abriata, Luciano A., Bayo, Yusupha, Bhabha, Gira, Breyton, Cécile, Caulton, Simon G., Chen, James, Degroux, Séraphine, Ekiert, Damian C., Erlandsen, Benedikte S., Freddolino, Peter L., Gilzer, Dominic, Greening, Chris, Grimes, Jonathan M., Grinter, Rhys, Gurusaran, Manickam, Hartmann, Marcus D., Hitchman, Charlie J., Keown, Jeremy R., Kropp, Ashleigh, Kursula, Petri, Lovering, Andrew L., Lemaitre, Bruno, Lia, Andrea, Liu, Shiheng, Logotheti, Maria, Lu, Shuze, Markússon, Sigurbjörn, Miller, Mitchell D., Minasov, George, Niemann, Hartmut H., Opazo, Felipe, Phillips, George N., Davies, Owen R., Rommelaere, Samuel, Rosas‐Lemus, Monica, Roversi, Pietro, Satchell, Karla, Smith, Nathan, Wilson, Mark A., Wu, Kuan‐Lin, Xia, Xian, Xiao, Han, Zhang, Wenhua, Zhou, Z. Hong, Fidelis, Krzysztof, Topf, Maya, Moult, John, Schwede, Torsten

“…We present an in‐depth analysis of selected CASP15 targets, focusing on their biological and functional significance. The authors of the structures identify…”
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PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism by van Diepen, Janna A, Jansen, Patrick A, Ballak, Dov B, Hijmans, Anneke, Hooiveld, Guido J, Rommelaere, Samuel, Galland, Franck, Naquet, Philippe, Rutjes, Floris P.J.T, Mensink, Ronald P, Schrauwen, Patrick, Tack, Cees J, Netea, Mihai G, Kersten, Sander, Schalkwijk, Joost, Stienstra, Rinke

“…Background & Aims Peroxisome proliferator-activated receptor alpha (PPARα) is a key regulator of hepatic fat oxidation that serves as an energy source during…”
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Blind killing of both male and female Drosophila embryos by a natural variant of the endosymbiotic bacterium Spiroplasma poulsonii by Masson, Florent, Calderon‐Copete, Sandra, Schüpfer, Fanny, Vigneron, Aurélien, Rommelaere, Samuel, Garcia‐Arraez, Mario G., Paredes, Juan C., Lemaitre, Bruno

“…Spiroplasma poulsonii is a vertically transmitted endosymbiont of Drosophila melanogaster that causes male‐killing, that is the death of infected male embryos…”
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Serum Pantetheinase/Vanin Levels Regulate Erythrocyte Homeostasis and Severity of Malaria by Rommelaere, Samuel, Millet, Virginie, Rihet, Pascal, Atwell, Scott, Helfer, Emmanuèle, Chasson, Lionel, Beaumont, Carole, Chimini, Giovanna, Sambo, Maria do Rosário, Viallat, Annie, Penha-Gonçalves, Carlos, Galland, Franck, Naquet, Philippe

“…Tissue pantetheinase, encoded by the VNN1 gene, regulates response to stress, and previous studies have shown that VNN genes contribute to the susceptibility…”
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Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses by Ferreira, Daniel W., Goedken, Michael J., Rommelaere, Samuel, Chasson, Lionel, Galland, Franck, Naquet, Philippe, Manautou, José E.

“…Pretreatment with clofibrate, a peroxisome proliferator-activated receptor alpha (PPARa) agonist, protects mice from acetaminophen (APAP) injury. Protection is…”
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