Search Results - "Romier‐Crouzet, Béatrice"
-
1
Elastic fibers and elastin receptor complex: Neuraminidase-1 takes the center stage
Published in Matrix biology (01-11-2019)“…Extracellular matrix (ECM) has for a long time being considered as a simple architectural support for cells. It is now clear that ECM presents a fundamental…”
Get full text
Journal Article -
2
X‐ray microtomography reveals a lattice‐like network within aortic elastic lamellae
Published in The FASEB journal (01-10-2021)“…The arterial wall consists of three concentric layers: intima, media, and adventitia. Beyond their resident cells, these layers are characterized by an…”
Get full text
Journal Article -
3
Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas
Published in International journal of molecular sciences (17-03-2022)“…Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the…”
Get full text
Journal Article -
4
The Elastin Receptor Complex: An Emerging Therapeutic Target Against Age-Related Vascular Diseases
Published in Frontiers in endocrinology (Lausanne) (11-02-2022)“…The incidence of cardiovascular diseases is increasing worldwide with the growing aging of the population. Biological aging has major influence on the vascular…”
Get full text
Journal Article -
5
Transmembrane Peptides as Inhibitors of Protein-Protein Interactions: An Efficient Strategy to Target Cancer Cells?
Published in Frontiers in oncology (15-04-2020)“…Cellular functions are regulated by extracellular signals such as hormones, neurotransmitters, matrix ligands, and other chemical or physical stimuli. Ligand…”
Get full text
Journal Article -
6
Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells
Published in Food and chemical toxicology (01-06-2009)“…The mitogen-activated protein kinases (MAPK) and nuclear factor κB (NF-κB) are involved in transduction cascades that play a key role in inflammatory response…”
Get full text
Journal Article -
7
Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production
Published in PloS one (18-06-2015)“…Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or…”
Get full text
Journal Article -
8
Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation
Published in Frontiers in cell and developmental biology (16-12-2020)“…Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers…”
Get full text
Journal Article -
9
Inhibition of neuraminidase-1 sialidase activity by interfering peptides impairs insulin receptor activity in vitro and glucose homeostasis in vivo
Published in The Journal of biological chemistry (01-06-2024)“…Neuraminidases (NEUs) also called sialidases are glycosidases which catalyze the removal of terminal sialic acid residues from glycoproteins, glycolipids, and…”
Get full text
Journal Article -
10
Role of elastin peptides and elastin receptor complex in metabolic and cardiovascular diseases
Published in The FEBS journal (01-08-2019)“…The Cardiovascular Continuum describes a sequence of events from cardiovascular risk factors to end‐stage heart disease. It includes conventional pathologies…”
Get full text
Journal Article -
11
Neuraminidase-1: A Sialidase Involved in the Development of Cancers and Metabolic Diseases
Published in Cancers (01-10-2022)“…Sialidases or neuraminidases (NEU) are glycosidases which cleave terminal sialic acid residues from glycoproteins, glycolipids and oligosaccharides. Four types…”
Get full text
Journal Article -
12
Revealing the elasticity of an individual aortic fiber during ageing at nanoscale by in situ atomic force microscopy
Published in Nanoscale (14-01-2021)“…Arterial stiffness is a complex process affecting the aortic tree that significantly contributes to cardiovascular diseases (systolic hypertension, coronary…”
Get more information
Journal Article -
13
Adverse Effects of Oseltamivir Phosphate Therapy on the Liver of LDLR−/− Mice Without Any Benefit on Atherosclerosis and Thrombosis
Published in Journal of cardiovascular pharmacology (01-05-2021)“…Desialylation, governed by sialidases or neuraminidases, is strongly implicated in a wide range of human disorders, and accumulative data show that inhibition…”
Get full text
Journal Article -
14
The Elastin Receptor Complex: A Unique Matricellular Receptor with High Anti-tumoral Potential
Published in Frontiers in pharmacology (04-03-2016)“…Elastin, one of the longest-lived proteins, confers elasticity to tissues with high mechanical constraints. During aging or pathophysiological conditions such…”
Get full text
Journal Article -
15
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-κB
Published in PloS one (18-06-2013)“…Immune cell infiltration of expanding adipose tissue during obesity and its role in insulin resistance has been described and involves chemokines. However,…”
Get full text
Journal Article -
16
Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation
Published in Journal of physiology and biochemistry (01-08-2020)“…Elastin, the major protein of the extracellular matrix, is specially found in cardiovascular tissues and contributing to 30–50% of the dry weight of blood…”
Get full text
Journal Article -
17
Adverse Effects of Oseltamivir Phosphate Therapy on the Liver of LDLR 2/2 Mice Without Any Benefit on Atherosclerosis and Thrombosis
Published in Journal of cardiovascular pharmacology (2021)“…Desialylation, governed by sialidases or neuraminidases, is strongly implicated in a wide range of human disorders, and accumulative data show that inhibition…”
Get full text
Journal Article -
18
-
19
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-[kappa]B
Published in PloS one (18-06-2013)“…Immune cell infiltration of expanding adipose tissue during obesity and its role in insulin resistance has been described and involves chemokines. However,…”
Get full text
Journal Article -
20
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF- Kappa B. e66515
Published in PloS one (01-06-2013)“…Immune cell infiltration of expanding adipose tissue during obesity and its role in insulin resistance has been described and involves chemokines. However,…”
Get full text
Journal Article