Search Results - "Romero‐Giménez, Jordi"
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Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis
Published in Nature communications (07-03-2019)“…In Parkinson’s disease (PD) there is a selective degeneration of neuromelanin-containing neurons, especially substantia nigra dopaminergic neurons. In humans,…”
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2
A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats
Published in Biomedicine & pharmacotherapy (01-10-2024)“…Many women have sought alternative therapies to address menopause. Recently, a multi-ingredient supplement (MIS) containing L-histidine, L-carnosine, L-serine,…”
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3
Brain magnetic resonance in experimental acute-on-chronic liver failure
Published in Liver international (01-02-2013)“…Background & Aim Acute‐on‐chronic liver failure is the term that refers to sustained liver injury with acute decompensation, usually induced by a precipitating…”
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4
Real-time assessment of 13C metabolism reveals an early lactate increase in the brain of rats with acute liver failure
Published in NMR in biomedicine (01-01-2015)“…Intracranial hypertension is a severe complication of acute liver failure (ALF) secondary to brain edema. The pathogenesis of cerebral edema in ALF is not…”
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5
Gene expression profiling of brain cortex microvessels may support brain vasodilation in acute liver failure rat models
Published in Metabolic brain disease (01-12-2016)“…Development of brain edema in acute liver failure can increase intracranial pressure, which is a severe complication of the disease. However, brain edema is…”
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6
Motor‐evoked potentials in awake rats are a valid method of assessing hepatic encephalopathy and of studying its pathogenesis
Published in Hepatology (Baltimore, Md.) (01-12-2010)“…Experimental models of hepatic encephalopathy (HE) are limited by difficulties in objectively monitoring neuronal function. There are few models that examine a…”
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7
Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families
Published in International journal of cancer (15-03-2008)“…Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome predisposing to colorectal cancer and affects 1 in 5–10,000 births. Inheritance of a…”
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8
In vivo reduction of age-dependent neuromelanin accumulation mitigates features of Parkinson’s disease
Published in Brain (London, England : 1878) (01-03-2023)“…Abstract Humans accumulate with age the dark-brown pigment neuromelanin inside specific neuronal groups. Neurons with the highest neuromelanin levels are…”
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Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy
Published in Journal of cerebral blood flow and metabolism (01-03-2017)“…Hepatic encephalopathy has traditionally been considered a reversible disorder. However, recent studies suggested that repeated episodes of hepatic…”
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10
Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits
Published in Nature communications (11-10-2024)“…One key limitation in developing effective treatments for neurodegenerative diseases is the lack of models accurately mimicking the complex physiopathology of…”
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11
Interaction of Diamine Oxidase with Psychostimulant Drugs for ADHD Management
Published in Journal of clinical medicine (13-07-2023)“…Histamine intolerance occurs when there is an imbalance between histamine production and the capacity for histamine degradation. Diamine oxidase (DAO) is the…”
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Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine
Published in Journal of clinical medicine (01-12-2023)“…Histamine intolerance arises when there is a disparity between the production of histamine and the body's ability to break it down. In the gastrointestinal…”
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13
Exploring the Relationship between Diamine Oxidase and Psychotropic Medications in Fibromyalgia Treatment, Finding No Reduction in Diamine Oxidase Levels and Activity except with Citalopram
Published in Journal of clinical medicine (30-01-2024)“…: Histamine intolerance manifests when there is an imbalance between the production of histamine and the body's capacity to metabolise it. Within the…”
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14
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis
Published in Journal of hepatology (01-01-2012)“…Background & Aims Ornithine phenylacetate (OP) is a new drug that has been proposed for the treatment of hepatic encephalopathy (HE) because it decreases…”
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15
Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson’s disease
Published in Cell death & disease (07-11-2018)“…Mitochondria are the prime energy source in most eukaryotic cells, but these highly dynamic organelles are also involved in a multitude of cellular events…”
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16
Diffusion Tensor Imaging Supports the Cytotoxic Origin of Brain Edema in a Rat Model of Acute Liver Failure
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2010)“…Background & Aims Brain edema is a severe complication of acute liver failure (ALF) that has been related to ammonia concentrations. Two mechanisms have been…”
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17
Preventive Treatment with Astaxanthin Microencapsulated with Spirulina Powder, Administered in a Dose Range Equivalent to Human Consumption, Prevents LPS-Induced Cognitive Impairment in Rats
Published in Nutrients (23-06-2023)“…Cognitive alterations are a common feature associated with many neurodegenerative diseases and are considered a major health concern worldwide. Cognitive…”
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18
EPHB4 and survival of colorectal cancer patients
Published in Cancer research (Chicago, Ill.) (15-09-2006)“…The family of receptor tyrosine kinases EPH and their Ephrin ligands regulate cell proliferation, migration, and attachment. An important role in colorectal…”
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19
Real‐time assessment of 13 C metabolism reveals an early lactate increase in the brain of rats with acute liver failure
Published in NMR in biomedicine (01-01-2015)“…Intracranial hypertension is a severe complication of acute liver failure (ALF) secondary to brain edema. The pathogenesis of cerebral edema in ALF is not…”
Get full text
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20
Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson’s Disease
Published in ACS nano (25-05-2021)“…Dopamine (DA) is one of the main neurotransmitters found in the central nervous system and has a vital role in the function of dopaminergic (DArgic) neurons. A…”
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