Search Results - "Romero, Maritza J"

Peroxynitrite Disrupts Endothelial Caveolae Leading to eNOS Uncoupling and Diminished Flow-Mediated Dilation in Coronary Arterioles of Diabetic Patients by CASSUTO, James, HUIJUAN DOU, CZIKORA, Istvan, SZABO, Andras, PATEL, Vijay S, KAMATH, Vinayak, DE CHANTEMELE, Eric Belin, FEHER, Attila, ROMERO, Maritza J, BAGI, Zsolt

“…Peroxynitrite (ONOO(-)) contributes to coronary microvascular dysfunction in diabetes mellitus (DM). We hypothesized that in DM, ONOO(-) interferes with the…”
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Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity by Romero, Maritza J, Platt, Daniel H, Tawfik, Huda E, Labazi, Mohamed, El-Remessy, Azza B, Bartoli, Manuela, Caldwell, Ruth B, Caldwell, Robert W

“…Increases in arginase activity have been reported in a variety of disease conditions characterized by vascular dysfunction. Arginase competes with NO synthase…”
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Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction by Dou, Huijuan, Feher, Attila, Davila, Alec C, Romero, Maritza J, Patel, Vijay S, Kamath, Vinayak M, Gooz, Monika Beck, Rudic, R Daniel, Lucas, Rudolf, Fulton, David J, Weintraub, Neal L, Bagi, Zsolt

“…OBJECTIVE—A disintegrin and metalloproteinase ADAM17 (tumor necrosis factor-α [TNF]–converting enzyme) regulates soluble TNF levels. We tested the hypothesis…”
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Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway by Shatanawi, Alia, Romero, Maritza J, Iddings, Jennifer A, Chandra, Surabhi, Umapathy, Nagavedi S, Verin, Alexander D, Caldwell, Ruth B, Caldwell, R William

“…Enhanced vascular arginase activity impairs endothelium-dependent vasorelaxation by decreasing l-arginine availability to endothelial nitric oxide (NO)…”
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Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein by Romero, Maritza J, Yue, Qian, Singla, Bhupesh, Hamacher, Jürg, Sridhar, Supriya, Moseley, Auriel S, Song, Chang, Mraheil, Mobarak A, Fischer, Bernhard, Zeitlinger, Markus, Chakraborty, Trinad, Fulton, David, Gan, Lin, Annex, Brian H, Csanyi, Gabor, Eaton, Douglas C, Lucas, Rudolf

“…Although both COVID-19 and non-COVID-19 ARDS can be accompanied by significantly increased levels of circulating cytokines, the former significantly differs…”
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Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction by Czikora, Istvan, Alli, Abdel A, Sridhar, Supriya, Matthay, Michael A, Pillich, Helena, Hudel, Martina, Berisha, Besim, Gorshkov, Boris, Romero, Maritza J, Gonzales, Joyce, Wu, Guangyu, Huo, Yuqing, Su, Yunchao, Verin, Alexander D, Fulton, David, Chakraborty, Trinad, Eaton, Douglas C, Lucas, Rudolf

“…is a major etiologic agent of bacterial pneumonia. Autolysis and antibiotic-mediated lysis of pneumococci induce release of the pore-forming toxin, pneumolysin…”
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Home blood pressure variability: a new target to monitor in chronic kidney disease patients with low eGFR? by Romero, Maritza J

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Role of growth hormone-releasing hormone in dyslipidemia associated with experimental type 1 diabetes by Romero, Maritza J., Lucas, Rudolf, Dou, Huijuan, Sridhar, Supriya, Czikora, Istvan, Mosieri, Eby M., Rick, Ferenc G., Block, Norman L., Sridhar, Subbaramiah, Fulton, David, Weintraub, Neal L., Bagi, Zsolt, Schally, Andrew V.

“…Dyslipidemia associated with triglyceride-rich lipoproteins (TRLs) represents an important residual risk factor for cardiovascular and chronic kidney disease…”
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Role of IL-6 in Angiotensin II-Induced Retinal Vascular Inflammation by Rojas, Modesto, Zhang, Wenbo, Lee, Dexter L, Romero, Maritza J, Nguyen, Doan T, Al-Shabrawey, Mohamed, Tsai, Nai-Tse, Liou, Gregory I, Brands, Michael W, Caldwell, Robert W, Caldwell, Ruth B

“…The production of proinflammatory cytokines has been shown to play a critical role in a variety of retinal vascular diseases. Angiotensin II and VEGF have been…”
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Arginase Activity Mediates Retinal Inflammation in Endotoxin-Induced Uveitis by Zhang, Wenbo, Baban, Babak, Rojas, Modesto, Tofigh, Sohrab, Virmani, Suvika K, Patel, Chintan, Behzadian, M. Ali, Romero, Maritza J, Caldwell, Robert W, Caldwell, Ruth B

“…Arginase has been reported to reduce nitric oxide bioavailability in cardiovascular disease. However, its specific role in retinopathy has not been studied. In…”
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The role of RhoA/Rho kinase pathway in endothelial dysfunction by Yao, Lin, Romero, Maritza J, Toque, Haroldo A, Yang, Guang, Caldwell, Ruth B, Caldwell, R William

“…Endothelial dysfunction is a key event in the development of vascular disease, and it precedes clinically obvious vascular pathology. Abnormal activation of…”
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p38 Mitogen-Activated Protein Kinase (MAPK) Increases Arginase Activity and Contributes to Endothelial Dysfunction in Corpora Cavernosa from Angiotensin-II-Treated Mice by Toque, Haroldo A., Romero, Maritza J., Tostes, Rita C., Shatanawi, Alia, Chandra, Surabhi, Carneiro, Zidonia N., Inscho, Edward W., Webb, Robert Clinton, Caldwell, Ruth B., Caldwell, Robert William

“…Angiotensin II (AngII) activates p38 mitogen-activated protein kinase (MAPK) and elevates arginase activity in endothelial cells. Upregulation of arginase…”
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Arginase 1 mediates increased blood pressure and contributes to vascular endothelial dysfunction in deoxycorticosterone acetate-salt hypertension by Toque, Haroldo A, Nunes, Kenia P, Rojas, Modesto, Bhatta, Anil, Yao, Lin, Xu, Zhimin, Romero, Maritza J, Webb, R Clinton, Caldwell, Ruth B, Caldwell, R William

“…Enhanced arginase (ARG) activity has been identified as a factor that reduces nitric oxide production and impairs endothelial function in vascular pathologies…”
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l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice by Romero, Maritza J, Yao, Lin, Sridhar, Supriya, Bhatta, Anil, Dou, Huijuan, Ramesh, Ganesan, Brands, Michael W, Pollock, David M, Caldwell, Ruth B, Cederbaum, Stephen D, Head, C Alvin, Bagi, Zsolt, Lucas, Rudolf, Caldwell, Robert W

“…Diabetic nephropathy (DN) is a major cause of end-stage renal disease, associated with endothelial dysfunction. Chronic supplementation of l-arginine (l-arg),…”
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Arginase 1: an unexpected mediator of pulmonary capillary barrier dysfunction in models of acute lung injury by Lucas, Rudolf, Czikora, Istvàn, Sridhar, Supriya, Zemskov, Evgeny A, Oseghale, Aluya, Circo, Sebastian, Cederbaum, Stephen D, Chakraborty, Trinad, Fulton, David J, Caldwell, Robert W, Romero, Maritza J

“…The integrity of epithelial and endothelial barriers in the lower airspaces of the lungs has to be tightly regulated, in order to prevent leakage and to assure…”
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Diabetes-induced vascular dysfunction involves arginase I by Romero, Maritza J, Iddings, Jennifer A, Platt, Daniel H, Ali, M Irfan, Cederbaum, Stephen D, Stepp, David W, Caldwell, Ruth B, Caldwell, Robert W

“…Arginase can cause vascular dysfunction by competing with nitric oxide synthase for l-arginine and by increasing cell proliferation and collagen formation,…”
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Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability by Lucas, Rudolf, Yang, Guang, Gorshkov, Boris A, Zemskov, Evgeny A, Sridhar, Supriya, Umapathy, Nagavedi S, Jezierska-Drutel, Agnieszka, Alieva, Irina B, Leustik, Martin, Hossain, Hamid, Fischer, Bernhard, Catravas, John D, Verin, Alexander D, Pittet, Jean-François, Caldwell, Ruth B, Mitchell, Timothy J, Cederbaum, Stephen D, Fulton, David J, Matthay, Michael A, Caldwell, Robert W, Romero, Maritza J, Chakraborty, Trinad

“…Antibiotics-induced release of the pore-forming virulence factor pneumolysin (PLY) in patients with pneumococcal pneumonia results in its presence days after…”
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Arginase in the vascular endothelium: friend or foe? by Lucas, Rudolf, Fulton, David, Caldwell, Robert William, Romero, Maritza J

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Vascular dysfunction in retinopathy—An emerging role for arginase by Caldwell, Ruth B, Zhang, Wenbo, Romero, Maritza J, Caldwell, R. William

“…Abstract Retinal neovascularization is a leading cause of visual disability. Retinal diseases involving neovascularization all follow the same progression,…”
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Novel mechanisms of endothelial dysfunction in diabetes by Yang, Guang, Lucas, Rudolf, Caldwell, Ruth, Yao, Lin, Romero, Maritza J, Caldwell, Robert W

“…Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This condition increases the risk of developing coronary, cerebrovascular,…”
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