Search Results - "Romero, Kimberly"

The B55α Subunit of PP2A Drives a p53-Dependent Metabolic Adaptation to Glutamine Deprivation by Reid, Michael A., Wang, Wen-I, Rosales, Kimberly Romero, Welliver, Meng Xu, Pan, Min, Kong, Mei

“…Glutamine is an essential nutrient for cancer cell survival and proliferation, yet the signaling pathways that sense glutamine levels remain uncharacterized…”
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The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis by Siskind, Leah J., Mullen, Thomas D., Romero Rosales, Kimberly, Clarke, Christopher J., Hernandez-Corbacho, María José, Edinger, Aimee L., Obeid, Lina M.

“…The BCL-2 family members BAK and BAX are required for apoptosis and trigger mitochondrial outer membrane permeabilization (MOMP). Here we identify a…”
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Ceramide starves cells to death by downregulating nutrient transporter proteins by Guenther, Garret G, Peralta, Eigen R, Rosales, Kimberly Romero, Wong, Susan Y, Siskind, Leah J, Edinger, Aimee L

“…Ceramide induces cell death in response to many stimuli. Its mechanism of action, however, is not completely understood. Ceramide induces autophagy in…”
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Profiling the Humoral Immune Response to Infection by Using Proteome Microarrays: High-Throughput Vaccine and Diagnostic Antigen Discovery by Davies, D. Huw, Liang, Xiaowu, Hernandez, Jenny E., Randall, Arlo, Hirst, Siddiqua, Mu, Yunxiang, Romero, Kimberly M., Nguyen, Toai T., Kalantari-Dehaghi, Mina, Crotty, Shane, Baldi, Pierre, Villarreal, Luis P., Felgner, Philip L., Nomura, Masayasu

“…Despite the increasing availability of genome sequences from many human pathogens, the production of complete proteomes remains at a bottleneck. To address…”
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Vitamin K2 Regulation of Bone Homeostasis Is Mediated by the Steroid and Xenobiotic Receptor SXR by Tabb, Michelle M., Sun, Aixu, Zhou, Changcheng, Grün, Felix, Errandi, Jody, Romero, Kimberly, Pham, Hang, Inoue, Satoshi, Mallick, Shyamali, Lin, Min, Forman, Barry M., Blumberg, Bruce

“…Vitamin K2 is a critical nutrient required for blood clotting that also plays an important role in bone formation. Vitamin K2 supplementation up-regulates the…”
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TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response by Rosales, Kimberly Romero, Reid, Michael A, Yang, Ying, Tran, Thai Q, Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei

“…Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this…”
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Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis by Romero Rosales, Kimberly, Peralta, Eigen R, Guenther, Garret G, Wong, Susan Y, Edinger, Aimee L

“…The Rab7 GTPase promotes membrane fusion reactions between late endosomes and lysosomes. In previous studies, we demonstrated that Rab7 inactivation blocks…”
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Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins by Romero Rosales, Kimberly, Singh, Gurpreet, Wu, Kevin, Chen, Jie, Janes, Matthew R, Lilly, Michael B, Peralta, Eigen R, Siskind, Leah J, Bennett, Michael J, Fruman, David A, Edinger, Aimee L

“…Cancer cells are hypersensitive to nutrient limitation because oncogenes constitutively drive glycolytic and TCA (tricarboxylic acid) cycle intermediates into…”
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Ruxolitinib and the Mitigation of Severe COVID-19: A Systematic Review and Meta-analysis by Quiros, Jorge R, Ross-Comptis, Jennifer, Hathaway, 3rd, Donald, Sarfraz, Azza, Sarfraz, Zouina, Grigoryan, Zhanna, Romero, Kimberly Anne, Gapizov, Abubakar, Príncipe-Meneses, Fortunato S, Somagutta, Manoj Reddy, Riva-Moscoso, Adrian, Kapasi, Abdulhusein

“…The cause of end-organ damage and acute respiratory distress syndrome (ARDS) in coronavirus disease 2019 (COVID-19) patients is postulated to be connected to…”
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TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response: e0145938 by Rosales, Kimberly Romero, Reid, Michael A, Yang, Ying, Tran, Thai Q, Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei

“…Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this…”
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Nutrient transporter regulation: A means to starve cancer cells to death by Rosales, Kimberly Romero

“…The molecular mechanisms that regulate nutrient transporter expression are poorly understood. Cells take in nutrients they require for growth and proliferation…”
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Nutrient transporter regulation: A means to starve cancer cells to death by Rosales, Kimberly Romero

“…The molecular mechanisms that regulate nutrient transporter expression are poorly understood. Cells take in nutrients they require for growth and proliferation…”
Get full text