Search Results - "Romer, Eric"

Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication by Gadgil, Rujuta Yashodhan, Romer, Eric J., Goodman, Caitlin C., Rider, S.Dean, Damewood, French J., Barthelemy, Joanna R., Shin-ya, Kazuo, Hanenberg, Helmut, Leffak, Michael

“…Short tandemly repeated DNA sequences, termed microsatellites, are abundant in the human genome. These microsatellites exhibit length instability and…”
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Examining cellular responses to reconstituted antibody protein liquids by Nelson, M. Tyler, Slocik, Joseph M., Romer, Eric J., Mankus, Cassandra I., Agans, Richard T., Naik, Rajesh R., Hussain, Saber M.

“…Protein ionic liquids (PIL) are a new class of biologic stabilizers designed to protect the functionality and extend the shelf-life of biotechnological and…”
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Systemic Platelet-Activating Factor-Receptor Agonism Enhances Non-Melanoma Skin Cancer Growth by Romer, Eric, Thyagarajan, Anita, Krishnamurthy, Smita, Rapp, Christine M, Liu, Langni, Fahy, Katherine, Awoyemi, Azeezat, Sahu, Ravi P

“…Platelet-activating factor-receptor (PAF-R) agonists are pleiotropic lipid factors that influence multiple biological processes, including the induction and…”
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Hydrogen peroxide modulates immunoglobulin expression by targeting the 3'Igh regulatory region through an NFκB-dependent mechanism by Romer, Eric J, Sulentic, Courtney E W

“…Reactive oxygen species such as hydrogen peroxide (H(2)O(2)) appear to play a role in signal transduction in immune cells and have been shown to be synthesized…”
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Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3′immunoglobulin heavy chain regulatory region by Henseler, Rebecca A, Romer, Eric J, Sulentic, Courtney E.W

“…Abstract 2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD), a known disruptor of B-cell differentiation and a ligand for the aryl hydrocarbon receptor (AhR),…”
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Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling by Zhu, Xiang, Schweitzer, Brock L, Romer, Eric J, Sulentic, Courtney E.W, DeKoter, Rodney P

“…Spi-C is an Ets family transcription factor closely related to PU.1 and Spi-B. Expression of Spi-C is developmentally regulated in the B-cell lineage, but its…”
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Determining the Biological Mechanisms of Action for Environmental Exposures: Applying CRISPR/Cas9 to Toxicological Assessments by Lujan, Henry, Romer, Eric, Salisbury, Richard, Hussain, Saber, Sayes, Christie

“…Abstract Toxicology is a constantly evolving field, especially in the area of developing alternatives to animal testing. Toxicological research must evolve and…”
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Protein Phosphatase 2A and Cdc7 Kinase Regulate the DNA Unwinding Element-binding Protein in Replication Initiation by Gao, Yanzhe, Yao, Jianhong, Poudel, Sumeet, Romer, Eric, Abu-Niaaj, Lubna, Leffak, Michael

“…The DNA unwinding element (DUE)-binding protein (DUE-B) binds to replication origins coordinately with the minichromosome maintenance (MCM) helicase and the…”
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Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms by Ocana, Jesus A, Romer, Eric, Sahu, Ravi, Pawelzik, Sven-Christian, FitzGerald, Garret A, Kaplan, Mark H, Travers, Jeffrey B

“…Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces…”
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Enhanced Platelet-Activating Factor Synthesis Facilitates Acute and Delayed Effects of Ethanol-Intoxicated Thermal Burn Injury by Harrison, Kathleen A., Romer, Eric, Weyerbacher, Jonathan, Ocana, Jesus A., Sahu, Ravi P., Murphy, Robert C., Kelly, Lisa E., Smith, Townsend A., Rapp, Christine M., Borchers, Christina, Cool, David R., Li, Gengxin, Simman, Richard, Travers, Jeffrey B.

“…Thermal burn injuries in patients who are alcohol-intoxicated result in greater morbidity and mortality. Murine models combining ethanol and localized thermal…”
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H 2 O 2 modulates the transcriptional regulation of the 3′IgH regulatory region via the NFκB Pathway by Romer, Eric J, Sulentic, Courtney E.W.

“…Abstract only…”
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H2O2 modulates the transcriptional regulation of the 3′IgH regulatory region via the NFκB Pathway by Romer, Eric J, Sulentic, Courtney E.W.

“…Transcription of the immunoglobulin heavy chain (IgH) in B lymphocytes is governed by a 3′IgH Regulatory Region (3′IgHRR) and is an essential step in antibody…”
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Hydrogen Peroxide Modulates the Transcriptional Regulation of the 3′IgH Regulatory Region via the NF-Kappa B Pathway by Romer, Eric J, Sulentic, Courtney E.W.

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Reactive Oxygen Species: Integral Components of B Cell Activation by Romer, Eric J, Fernando, Tharu M, Sulentic, Courtney E.W.

“…Abstract only The transcription of the immunoglobulin heavy chain (IgH) which is governed by the 3'IgH Regulatory Region (3'IgH RR) in activated B cells is a…”
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Ectopic Expression of Spi‐C Impairs B Cell Development and Function by DeKoter, Rodney P, Schweitzer, Brock L, Romer, Eric J, Sulentic, Courtney E. W., Zhu, Xiang

“…Spi‐C is an Ets family transcription factor closely related to PU.1 and Spi‐B. Expression of Spi‐C is developmentally regulated in the B cell lineage, but its…”
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Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region by HENSELER, Rebecca A, ROMER, Eric J, SULENTIC, Courtney E. W

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a known disruptor of B-cell differentiation and a ligand for the aryl hydrocarbon receptor (AhR), induces binding…”
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