Search Results - "Romea, P"

Unconventional Biradical Character of Titanium Enolates by Moreira, I. de P. R, Bofill, J. M, Anglada, J. M, Solsona, J. G, Nebot, J, Romea, P, Urpí, F

“…Experimental and theoretical studies evidence an unconventional biradical character for the titanium enolates derived from α-alkoxy ketones and TiCl4. EPR…”
Get full text

Stereoselective Synthesis of the Western Hemisphere of Salinomycin by Larrosa, Igor, Romea, Pedro, Urpí, Fèlix

“…A convergent and module-based strategy for the asymmetric synthesis of the western hemisphere (C1−C17 fragment) of salinomycin has been devised. This new…”
Get full text

Highly Stereoselective Aldol Reaction Based on Titanium Enolates from (S)-1-Benzyloxy-2-methyl-3-pentanone by Solsona, Joan G, Nebot, Joaquim, Romea, Pedro, Urpí, Fèlix

“…Alternative titanium-mediated aldol procedures based on several protected β-hydroxy ethyl ketones have been surveyed. Eventually, enolization of…”
Get full text

Highly Stereoselective Aldol Reactions of Titanium Enolates from Lactate-Derived Chiral Ketones by Solsona, Joan G, Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…Highly stereoselective titanium-mediated aldol reactions based on lactate-derived ketones are reported. The stereochemical outcome of the process depends on…”
Get full text

Studies Directed toward the Construction of the Polypropionate Fragment of Superstolide A by Solsona, Joan G, Romea, Pedro, Urpí, Fèlix

“…Highly stereoselective approaches directed toward the synthesis of the C18−C27 fragment of superstolide A are disclosed taking ketone 6 and aldehyde 7 as the…”
Get full text

Unprecedented Highly Stereoselective α- and β-C-Glycosidation with Chiral Titanium Enolates by Larrosa, Igor, Romea, Pedro, Urpí, Fèlix, Balsells, Daniel, Vilarrasa, Jaume, Font-Bardia, Mercè, Solans, Xavier

“…Lewis acid mediated addition of chiral titanium enolates to glycals provides either α- or β-1‘-methyl-substituted C-glycosides. This highly stereoselective…”
Get full text

Stereoselective titanium-mediated syn -aldol reaction from a lactate-derived chiral ethyl ketone by Solsona, Joan G, Romea, Pedro, Urpı́, Fèlix

Get full text

Enantioselective Addition of a Chiral Thiazolidinethione-Derived Titanium Enolate to Acetals by Cosp, Annabel, Romea, Pedro, Talavera, Pere, Urpí, Fèlix, Vilarrasa, Jaume, Font-Bardia, Mercè, Solans, Xavier

“…High stereoselectivities (up to 98% de) have been achieved for the Lewis acid-mediated cross-coupling reaction of dimethyl acetals to a chiral…”
Get full text

Enantiopure β-methoxy carboxyl derivatives from a chiral titanium enolate and dimethyl acetals by Cosp, Annabel, Romea, Pedro, Urpı́, Fèlix, Vilarrasa, Jaume

“…Lewis acid-mediated reaction of the titanium enolate arising from ( S)- N-acetyl-4-isopropyl-1,3-thiazolidine-2-thione with dimethyl acetals furnishes…”
Get full text

Studies on the Intramolecular C−H···X (X = O, S) Interactions in (S)-N-Acyl- 4-isopropyl-1,3-thiazolidine-2-thiones and Related 1,3-Oxazolidin-2-ones by Cosp, Anabel, Larrosa, Igor, Anglada, Josep M, Bofill, Josep M, Romea, Pedro, Urpí, Fèlix

“…Two intramolecular C−H···X (X = O, S) interactions in (S)-N-acyl-4-isopropyl-1,3-thiazolidine-2-thiones are documented through crystallographic and…”
Get full text

Stereoselective synthesis of syn, syn-2-methyl-1,3-diols through one-pot aldol–reduction sequence by Galobardes, Marta, Mena, Marisa, Romea, Pedro, Urpı́, Fèlix, Vilarrasa, Jaume

“…Chx 2BCl-mediated syn-aldol reaction of the α-OTBS lactate-derived ketone 1 followed by in situ reduction of the resulting boron aldolate with LiBH 4 lead to…”
Get full text

Reaction of achiral titanium Z-enolates with chiral α-silyloxy aldehydes by Esteve, Cristina, Ferreró, Mònica, Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…Aldol reactions between the putative Z-enolate derived from 2-methyl-3-pentanone and several chiral α-tert-butyldiphenylsilyloxy aldehydes have been studied…”
Get full text

Reaction of chiral titanium Z-enolates with chiral α-silyloxy aldehydes. Syntheses of NFX-2 and Antimycinone by Esteve, Cristina, Ferreró, Mònica, Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…Titanium-mediated aldol reactions of 1 and (S)-2-tert-butyldiphenylsilyloxy aldehydes (matched pair) afford syn Felkin diastereomers in excellent yield and…”
Get full text

Enolization of Chiral α-Silyloxy Ketones with Dicyclohexylchloroborane. Application to Stereoselective Aldol Reactions by Galobardes, Marta, Gascón, Miguel, Mena, Marisa, Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…Comprehensive analysis of the enolization of α-silyloxyketones by Chx2BCl/R3N has allowed us to design stereoselective Chx2BCl-mediated aldol processes that…”
Get full text

Highly stereoselective aldol reactions of titanium enolates from ethyl α-silyloxyalkyl ketones by Figueras, Sergi, Martín, Ricardo, Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…Aldol-like reactions of titanium enolates derived from α-OH, α-OBn, and α-OTBS ketones with a series of aldehydes have been studied. In sharp contrast to the…”
Get full text

Design and synthesis of a novel cyclo-β-tetrapeptide by Sutton, Peter W., Bradley, Adrian, Elsegood, Mark R.J., Farràs, Jaume, Jackson, Richard F.W., Romea, Pedro, Urpí, Fèlix, Vilarrasa, Jaume

“…N-Substituted tetralactams (cyclo-β-tetrapeptides) have been identified as potential molecular scaffolds by computer-aided design; compound 2, arising from…”
Get full text

A simple procedure for the preparation of enantiopure ethyl α-hydroxyalkyl ketones by Martín, Ricardo, Pascual, Oscar, Romea, Pedro, Rovira, Roser, Urpí, Fèlix, Vilarrasa, Jaume

“…Amides derived from pyrrolidine and methyl ( S)-lactate, methyl ( S)-2-hydroxy-3-phenylpropanoate, or methyl ( S)-2-hydroxy-3-methylbutanoate, after…”
Get full text

Syntheses of the C-1 alkyl side chains of Zaragozic acids A and C by Bach, Jordi, Galobardes, Marta, Garcia, Jordi, Romea, Pedro, Tey, Cristina, Urpí, Fèlix, Vilarrasa, Jaume

“…Asymmetric syntheses of the C-1 alkyl side chains of Zaragozic acids A and C from a common chiral precursor 4 are reported. The stereoselective reduction of…”
Get full text

Improved methods for the N-nitration of amides by Romea, Pedro, Aragones, Montse, Garcia, Jordi, Vilarrasa, Jaume

Get full text

Substrate-Controlled Aldol Reactions of Chiral Ethyl Ketones: Application to the Total Synthesis of Oleandomycin by Paterson, Ian, Ward, Richard A, Romea, Pedro, Norcross, Roger D

Get full text