Search Results - "Rome, Michael"
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The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor
Published in Structure (London) (04-03-2014)“…Mitochondrial fission requires recruitment of dynamin-related protein 1 (Drp1) to the mitochondrial surface and activation of its GTP-dependent scission…”
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Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins
Published in Cell (28-03-2013)“…The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein substrate receptors that enable recognition of diverse…”
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3
Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway
Published in Proceedings of the National Academy of Sciences - PNAS (18-11-2014)“…Efficient and accurate localization of membrane proteins requires a complex cascade of interactions between protein machineries. This requirement is…”
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4
Precise timing of ATPase activation drives targeting of tail-anchored proteins
Published in Proceedings of the National Academy of Sciences - PNAS (07-05-2013)“…The localization of tail-anchored (TA) proteins, whose transmembrane domain resides at the extreme C terminus, presents major challenges to cellular protein…”
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5
Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4
Published in Nature structural & molecular biology (01-05-2014)“…Tail-anchor proteins are targeted post-translationally to the endoplasmic reticulum via the conserved GET pathway, in which the Get4–Get5 complex mediates…”
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6
Vault Nanoparticles: Chemical Modifications for Imaging and Enhanced Delivery
Published in ACS nano (24-01-2017)“…Vault nanoparticles represent promising vehicles for drug and probe delivery. Innately found within human cells, vaults are stable, biocompatible nanocapsules…”
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Intervacuolar Transport and Unique Topology of GRA14, a Novel Dense Granule Protein in Toxoplasma gondii
Published in Infection and Immunity (01-11-2008)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting
Published in The Journal of biological chemistry (11-12-2015)“…Tail-anchored (TA) proteins, defined as having a single transmembrane helix at their C terminus, are post-translationally targeted to the endoplasmic reticulum…”
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9
Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue
Published in The EMBO journal (01-02-2012)“…Efficient delivery of membrane proteins is a critical cellular process. The recently elucidated GET ( G uided E ntry of T A proteins) pathway is responsible…”
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10
Association of shank 1A scaffolding protein with cone photoreceptor terminals in the mammalian retina
Published in PloS one (12-09-2012)“…Photoreceptor terminals contain post-synaptic density (PSD) proteins e.g., PSD-95/PSD-93, but their role at photoreceptor synapses is not known. PSDs are…”
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11
A Thioredoxin Family Protein of the Apicoplast Periphery Identifies Abundant Candidate Transport Vesicles in Toxoplasma gondii
Published in Eukaryotic Cell (01-09-2008)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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12
The ATPase Cycle of the Tail‐Anchored Protein Chaperone Get3
Published in The FASEB journal (01-04-2013)“…Abstract only The cytosolic ATPase Get3/TRC40 mediates targeting of tail‐anchored (TA) membrane proteins to the endoplasmic reticulum (ER). Get3 functions as a…”
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13
Regulation of the Get3 ATPase Cycle
Published in The FASEB journal (01-04-2012)“…Abstract only The cytosolic ATPase Get3/TRC40 mediates targeting of tail‐anchored (TA) membrane proteins to the endoplasmic reticulum (ER). Get3 functions as a…”
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14
Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting
Published in The Journal of cell biology (23-08-2010)“…The signal recognition particle (SRP) and SRP receptor comprise the major cellular machinery that mediates the cotranslational targeting of proteins to…”
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15
Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway
Published in Proceedings of the National Academy of Sciences - PNAS (18-11-2014)Get full text
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16
Regulation of mitochondrial fission by MiD51 (757.1)
Published in The FASEB journal (01-04-2014)“…Regulation of mitochondrial fission by MiD51 Oliver C. Losόn1, Michael E. Rome1, Jens T. Kaiser2, Shu‐ou Shan2 and David C. Chan1,3 1Division of Biology and…”
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17
Precise Timing of ATPase Activation Drives Targeting of Tail-Anchored Proteins
Published in Biophysical journal (29-01-2013)Get full text
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18
Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue: A tetrameric model for Get3 tail-anchor targeting
Published in The EMBO journal (01-02-2012)Get full text
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19
Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting
Published in The FASEB journal (01-04-2011)“…The highly conserved co‐translational protein targeting machinery comprised of the signal recognition particle (SRP) and its receptor (SR) is responsible for…”
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20
The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins
Published 01-01-2014“…Efficient and accurate localization of membrane proteins is essential to all cells and requires a complex cascade of interactions between protein machineries…”
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