Search Results - "Romberger, Debra"

Respiratory Health Effects of Large Animal Farming Environments by May, Sara, Romberger, Debra J., Poole, Jill A.

“…With increases in large animal-feeding operations to meet consumer demand, adverse upper and lower respiratory health effects in exposed agriculture workers…”
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Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice by Nordgren, Tara M., Heires, Art J., Zempleni, Janos, Swanson, Benjamin J., Wichman, Christopher, Romberger, Debra J.

“…Occupational agricultural dust exposure can cause severe lung injury, including COPD and asthma exacerbations. Cell-derived extracellular vesicles can mediate…”
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Shotgun pyrosequencing metagenomic analyses of dusts from swine confinement and grain facilities by Boissy, Robert J, Romberger, Debra J, Roughead, William A, Weissenburger-Moser, Lisa, Poole, Jill A, LeVan, Tricia D

“…Inhalation of agricultural dusts causes inflammatory reactions and symptoms such as headache, fever, and malaise, which can progress to chronic airway…”
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Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA by Heires, Art J., Samuelson, Derrick, Villageliu, Daniel, Nordgren, Tara M., Romberger, Debra J.

“…Dietary long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA) and their pro-resolving metabolites are protective against atherosclerotic disease, and…”
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Post-endotoxin exposure-induced lung inflammation and resolution consequences beneficially impacted by lung-delivered IL-10 therapy by Poole, Jill A., Gaurav, Rohit, Schwab, Aaron, Nelson, Amy J., Gleason, Angela, Romberger, Debra J., Wyatt, Todd A.

“…Although lung diseases typically result from long-term exposures, even a robust, one-time exposure can result in long-lasting consequences. Endotoxin is a…”
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Immunological and inflammatory responses to organic dust in agriculture by Poole, Jill A, Romberger, Debra J

“…PURPOSE OF REVIEWAgriculture represents a major industry worldwide, and despite protection against the development of IgE-mediated diseases, chronic exposure…”
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Short term dynamics of the sputum microbiome among COPD patients by Sinha, Rohita, Weissenburger-Moser, Lisa A, Clarke, Jennifer L, Smith, Lynette M, Heires, Art J, Romberger, Debra J, LeVan, Tricia D

“…Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder characterized by incompletely reversible airflow obstruction. The complexity of the…”
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High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis by Gaurav, Rohit, Mikuls, Ted R, Thiele, Geoffrey M, Nelson, Amy J, Niu, Meng, Guda, Chittibabu, Eudy, James D, Barry, Austin E, Wyatt, Todd A, Romberger, Debra J, Duryee, Michael J, England, Bryant R, Poole, Jill A

“…Rheumatoid arthritis (RA)-associated lung disease is a leading cause of mortality in RA, yet the mechanisms linking lung disease and RA remain unknown. Using…”
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Combined Collagen‐Induced Arthritis and Organic Dust‐Induced Airway Inflammation to Model Inflammatory Lung Disease in Rheumatoid Arthritis by Poole, Jill A, Thiele, Geoffrey M, Janike, Katherine, Nelson, Amy J, Duryee, Michael J, Rentfro, Kathryn, England, Bryant R, Romberger, Debra J, Carrington, Joseph M, Wang, Dong, Swanson, Benjamin J, Klassen, Lynell W, Mikuls, Ted R

“…ABSTRACT Rheumatoid arthritis (RA) is characterized by extra‐articular involvement including lung disease, yet the mechanisms linking the two conditions are…”
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Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists by Bailey, Kristina L., Smith, Lynette M., Heires, Art J., Katafiasz, Dawn M., Romberger, Debra J., LeVan, Tricia D.

“…Background Sepsis is more common in the elderly. TNF⍺ is recognized as an important mediator in sepsis and Toll-like receptors (TLRs) play an important role in…”
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Amphiregulin modulates murine lung recovery and fibroblast function following exposure to agriculture organic dust by Poole, Jill A, Nordgren, Tara M, Heires, Art J, Nelson, Amy J, Katafiasz, Dawn, Bailey, Kristina L, Romberger, Debra J

“…Exposure to agricultural bioaerosols can lead to chronic inflammatory lung diseases. Amphiregulin (AREG) can promote the lung repair process but can also lead…”
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Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust by Nordgren, Tara M, Heires, Art J, Wyatt, Todd A, Poole, Jill A, LeVan, Tricia D, Cerutis, D Roselyn, Romberger, Debra J

“…Exposure to organic dust causes detrimental airway inflammation. Current preventative and therapeutic measures do not adequately treat resulting disease,…”
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Anesthesia-related Cardiac Arrest by ELLIS, Sheila J, NEWLAND, Myrna C, LISCO, Steven J, SIMONSON, Jean A, PETERS, K. Reed, ROMBERGER, Debra J, MERCER, David W, TINKER, John H, HARTER, Ronald L, KINDSCHER, James D, FANG QIU

“…Much is still unknown about the actual incidence of anesthesia-related cardiac arrest in the United States. The authors identified all of the cases of cardiac…”
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Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures by Schwab, Aaron D, Wyatt, Todd A, Moravec, Grace, Thiele, Geoffrey M, Nelson, Amy J, Gleason, Angela, Schanze, Oliver, Duryee, Michael J, Romberger, Debra J, Mikuls, Ted R, Poole, Jill A

“…Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS)…”
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Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust by Warren, Kristi J, Dickinson, John D, Nelson, Amy J, Wyatt, Todd A, Romberger, Debra J, Poole, Jill A

“…Agriculture exposures are associated with reducing the risk of allergy and asthma in early life; yet, repeated exposures later in life are associated with…”
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Lung-delivered IL-10 therapy elicits beneficial effects via immune modulation in organic dust exposure-induced lung inflammation by Schwab, Aaron D, Wyatt, Todd A, Nelson, Amy J, Gleason, Angela, Gaurav, Rohit, Romberger, Debra J, Poole, Jill A

“…Efficacious therapeutic options capable of resolving inflammatory lung disease associated with environmental and occupational exposures are lacking. This study…”
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Unique transcriptomic profile of peripheral blood monocytes in rheumatoid arthritis-associated interstitial lung disease by Poole, Jill A, Schwab, Aaron, Thiele, Geoffrey M, England, Bryant R, Nelson, Amy J, Gleason, Angela, Duryee, Michael J, Bailey, Kristina L, Romberger, Debra J, Hershberger, Daniel, Van De Graaff, Joel, May, Sara M, Walenz, Rhonda, Kramer, Bridget, Mikuls, Ted R

“…Though interstitial lung disease (ILD) contributes to excess morbidity and mortality in rheumatoid arthritis (RA), RA-ILD pathogenesis remains incompletely…”
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Relationships of serum CC16 levels with smoking status and lung function in COPD by Gribben, Kelli C, Poole, Jill A, Nelson, Amy J, Farazi, Paraskevi A, Wichman, Christopher S, Heires, Art J, Romberger, Debra J, LeVan, Tricia D

“…The club cell secretory protein (CC16) has anti-inflammatory and antioxidant effects, and low CC16 serum levels have been associated with both risk and…”
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A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts by Ulu, Arzu, Burr, Abigail, Heires, Art J., Pavlik, Jacqueline, Larsen, Tricia, Perez, Pedro A., Bravo, Carissa, DiPatrizio, Nicholas V., Baack, Michelle, Romberger, Debra J., Nordgren, Tara M.

“…Agricultural workers, especially those who work in swine confinement facilities, are at increased risk for developing pulmonary diseases including asthma,…”
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IL-33 Depletion in COVID-19 Lungs by Gaurav, Rohit, Anderson, Daniel R., Radio, Stanley J., Bailey, Kristina L., England, Bryant R., Mikuls, Ted R., Thiele, Geoffrey M., Strah, Heather M., Romberger, Debra J., Wyatt, Todd A., Dickinson, John D., Duryee, Michael J., Katafiasz, Dawn M., Nelson, Amy J., Poole, Jill A.

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